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  1. Brucellosis is a zoonotic disease caused by Brucella spp. In Nepal, the presence of brucellosis in small ruminants, namely sheep and goats, has impacted farmers’ livelihood and the food safety of consumers. A cro...

    Authors: Tulsi Ram Gompo, Rubina Shah, Ishwari Tiwari and Yam Bahadur Gurung

    Citation: BMC Veterinary Research 2021 17:132

    Content type: Research article

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  2. Transmission of antimicrobial resistant and virulent Escherichia coli (E. coli) from animal to human has been considered as a public health concern. This study aimed to determine the phylogenetic background and p...

    Authors: Pouya Reshadi, Fatemeh Heydari, Reza Ghanbarpour, Mahboube Bagheri, Maziar Jajarmi, Mohadese Amiri, Hesam Alizade, Mahdi Askari Badouei, Shademan Sahraei and Nasrin Adib

    Citation: BMC Veterinary Research 2021 17:131

    Content type: Research article

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  3. Invasive micropapillary carcinoma (IMPC) is a rare malignant breast tumor and a variant form of invasive ductal carcinoma that is an aggressive neoplasm of the human breast and canine mammary gland. The import...

    Authors: Michele A. Rodrigues, Andre L. Caldeira-Brant, Dawidson A. Gomes, Tatiany L. Silveira, Hélio Chiarini-Garcia and Geovanni D. Cassali

    Citation: BMC Veterinary Research 2021 17:130

    Content type: Research article

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  4. Diagnosis of canine bacterial pneumonia relies on airway lavage to confirm septic, suppurative inflammation, and a positive bacterial culture. Considering risks of bronchoalveolar lavage fluid (BALF) collectio...

    Authors: A. I. Vientós-Plotts, A. C. Ericsson, H. Rindt and C. R. Reinero

    Citation: BMC Veterinary Research 2021 17:129

    Content type: Research article

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  5. Morbilliviruses are categorized under the family of Paramyxoviridae and have been associated with severe diseases, such as Peste des petits ruminants, canine distemper and measles with evidence of high morbidity ...

    Authors: Siti Tasnim Makhtar, Sheau Wei Tan, Nur Amalina Nasruddin, Nor Azlina Abdul Aziz, Abdul Rahman Omar and Farina Mustaffa-Kamal

    Citation: BMC Veterinary Research 2021 17:128

    Content type: Research article

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  6. Cryopreservation is an efficient way to store spermatozoa and is closely associated with the quality of sperm after the freeze-thaw process. During freeze-thaw cycling, excessive reactive oxygen species (ROS) ...

    Authors: Bin Zhang, Yan Wang, Caihong Wu, Shulei Qiu, Xiaolan Chen, Bingyan Cai and Huimei Xie

    Citation: BMC Veterinary Research 2021 17:127

    Content type: Research article

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  7. A novel Brucella strain closely related to Brucella (B.) melitensis biovar (bv) 3 was found in Croatian cattle during testing within a brucellosis eradication programme.

    Authors: Silvio Spicic, Maja Zdelar-Tuk, Claire Ponsart, Rene S. Hendriksen, Irena Reil, Guillaume Girault, Pimlapas Leekitcharoenphon, Vesna Rukavina, Martina Rubin, Luca Freddi and Sanja Duvnjak

    Citation: BMC Veterinary Research 2021 17:126

    Content type: Case Report

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  8. The rehabilitation of injured wildlife and their subsequent release into the wild is a humane act as well as important in wildlife conservation. However, little is known about the animals’ fate after release. ...

    Authors: Dong-Hyuk Jeong, Kwangsik Jang, Jeong-Jin Yang, Joo-Yeul Choi, Seung-Hyo Lim, Seong-Chan Yeon, Kyung Mi Shim, Se Eun Kim and Seong Soo Kang

    Citation: BMC Veterinary Research 2021 17:125

    Content type: Case Report

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  9. Influenza viruses are a continuous threat to avian and mammalian species, causing epidemics and pandemics. After the circulation of H5N1 in 2006, 2015, and 2016 in Iraq, an H5N8 influenza virus emerged in dome...

    Authors: Nahla Muhammad Saeed, Peshnyar Muhammad Atta Rashid and Hiewa Othman Dyary

    Citation: BMC Veterinary Research 2021 17:124

    Content type: Research article

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  10. Immunization of pigs with an inactivated Mycoplasma hyopneumoniae vaccine (bacterin) generates hyperimmune serum that contains high concentrations of anti-M. hyopneumoniae IgG. Commercially available IgG-ELISA ki...

    Authors: Yaqin Tian, Zuobo Xu, Yukang Wen, Mei Yang, Yaru Ning, Zhaodi Wang and Honglei Ding

    Citation: BMC Veterinary Research 2021 17:123

    Content type: Methodology article

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  11. The intramuscular injection of ketamine and azaperone was proposed as a suitable anaesthesia for male suckling piglets for surgical castration. However, this can be opposed by massive defensive movements, hypo...

    Authors: Sabrina Becker, Anna Maier, Saskia Peters, Kathrin Büttner and Gerald Reiner

    Citation: BMC Veterinary Research 2021 17:122

    Content type: Research article

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  12. Glycogen in skeletal muscle is a major source of energy during exercise and an important determinant of endurance capacity, so that its measurement may provide a meaningful marker of athletes’ preparation and ...

    Authors: Sarah A. Tabozzi, Giovanni Stancari, Enrica Zucca, Michela Tajoli, Luca Stucchi, Claudio L. Lafortuna and Francesco Ferrucci

    Citation: BMC Veterinary Research 2021 17:121

    Content type: Research article

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  13. The aim of this study was to establish precision-cut bovine udder slices (PCBUS) as an in-vitro-model to investigate pathophysiological processes in the early phase of mastitis in order to have the possibility...

    Authors: Viviane Filor, Monique Petry, Jessica Meißner and Manfred Kietzmann

    Citation: BMC Veterinary Research 2021 17:120

    Content type: Research article

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  14. Inflammation is believed to influence human colorectal carcinogenesis and may have an impact on prognosis and survival. The mucosal immunophenotype in dogs with colorectal cancer is poorly described.

    Authors: Kristin M. V. Herstad, Gjermund Gunnes, Runa Rørtveit, Øyvor Kolbjørnsen, Linh Tran and Ellen Skancke

    Citation: BMC Veterinary Research 2021 17:119

    Content type: Research article

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  15. Anaplasma are obligate intracellular bacteria and aetiological agents of tick-borne diseases of both veterinary and medical interest. The genus Anaplasma comprises six species: Anaplasma marginale, Anaplasma cent...

    Authors: Łukasz Adaszek, Anna Wilczyńska, Jerzy Ziętek, Marcin Kalinowski, Oliwier Teodorowski, Dagmara Winiarczyk, Maciej Skrzypczak and Stanisław Winiarczyk

    Citation: BMC Veterinary Research 2021 17:118

    Content type: Case Report

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  16. At present, the process of inspection and quarantine starts with sampling at the customs port, continues with transporting the samples to the central laboratory for inspection experiments, and ends with the in...

    Authors: Yan Jiang, Shan Jiang, Yue Wu, Bin Zhou, Kaimin Wang, Luyan Jiang, Yunfeng Long, Gan Chen and Dexin Zeng

    Citation: BMC Veterinary Research 2021 17:117

    Content type: Methodology article

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  17. Selection pressure exerted by use of antibiotics in both human and veterinary medicine is responsible for increasing antimicrobial resistance (AMR). The objectives of this study were to better understand antim...

    Authors: Gaëlle Gruel, Arantxa Sellin, Hélène Riveiro, Matthieu Pot, Sébastien Breurec, Stéphanie Guyomard-Rabenirina, Antoine Talarmin and Séverine Ferdinand

    Citation: BMC Veterinary Research 2021 17:116

    Content type: Research article

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  18. After a decade of silence, an outbreak of the contagious and Asian endemic disease, goat pox re-emerged in North Vietnam affecting more than 1800 heads with a mortality rate of 6.5%. The inevitable impact of g...

    Authors: Trang Hong Pham, Nor Yasmin Abdul Rahaman, Mohd Azmi Mohd Lila, Huong Lan Thi Lai, Lan Thi Nguyen, Giap Van Nguyen, Bo Xuan Ha, Hieu Nguyen, Hanh Duc Vu and Mustapha M. Noordin

    Citation: BMC Veterinary Research 2021 17:115

    Content type: Research article

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  19. Pyroptosis plays a pivotal role in the pathogenesis of many inflammatory diseases. The molecular mechanism by which pyroptosis is induced in macrophages following infection with pathogenic E. coli high pathogenic...

    Authors: Chunlan Shan, Shushu Miao, Chaoying Liu, Bo Zhang, Weiwei Zhao, Hao Wang, Wei Yang, Jinlong Cha, Ru Zhao, Peng Xiao and Hong Gao

    Citation: BMC Veterinary Research 2021 17:114

    Content type: Research article

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  20. Pet dogs are important companion animals that share the environment within households, and play an important role in local community life. In addition, pet dogs also are reservoirs of zoonotic agents, including R...

    Authors: Jian-Wei Shao, Xin-Yan Yao, Xu-Dong Song, Wen-Jun Li, Hui-Lan Huang, Shu-Jian Huang and Xue-Lian Zhang

    Citation: BMC Veterinary Research 2021 17:113

    Content type: Research article

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  21. Dogs are domesticated wolves. Change of living environment, such as diet and veterinary care may affect the gut bacterial flora of dogs. The aim of this study was to assess the gut bacterial diversity and func...

    Authors: Yuting Liu, Bo Liu, Chengwu Liu, Yumiao Hu, Chang Liu, Xiaoping Li, Xibao Li, Xiaoshuang Zhang, David M. Irwin, Zhiqiang Wu, Zeliang Chen, Qi Jin and Shuyi Zhang

    Citation: BMC Veterinary Research 2021 17:112

    Content type: Research article

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  22. Erysipelas, caused by Erysipelothrix rhusiopathiae (ER), is an important emerging disease in free-range and organic egg-production. The aim of the present study was to assess if quantification of ER specific IgY ...

    Authors: Eva Wattrang, Helena Eriksson, Ann Albihn and Tina Sørensen Dalgaard

    Citation: BMC Veterinary Research 2021 17:111

    Content type: Research article

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  23. Objective outcome measures capable of tracking different aspects of functional recovery in dogs with acute intervertebral disc herniation are needed to optimize physical rehabilitation protocols. Normal, pre-i...

    Authors: Jessica E. Linder, Stephanie Thomovsky, Jessica Bowditch, Mallory Lind, Kristine A. Kazmierczak, Gert J. Breur and Melissa J. Lewis

    Citation: BMC Veterinary Research 2021 17:110

    Content type: Research article

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  24. Effective animal health surveillance systems require reliable, high-quality, and timely data for decision making. In Tanzania, the animal health surveillance system has been relying on a few data sources, whic...

    Authors: Janeth George, Barbara Häsler, Erick Komba, Calvin Sindato, Mark Rweyemamu and James Mlangwa

    Citation: BMC Veterinary Research 2021 17:109

    Content type: Research article

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  25. Candida is the common conditionally pathogenic fungus that infected human and animal clinically. C. tropicalis had been isolated from the skin and hair of healthy pigs, but with no report of fatal infection in ga...

    Authors: Lufeng Zhai, Ying Zhou, Yingxia Wu, Yunyun Jin, Qiaoyan Zhu, Shengguo Gao, Xuefeng Li, Zhe Sun, Yan Xiao, Baicheng Huang and Kegong Tian

    Citation: BMC Veterinary Research 2021 17:108

    Content type: Case Report

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  26. Klebsiella pneumonia, a Gram-negative bacterium belonging to the genus Enterobacter, causes many human and livestock diseases. Notably, infected goats may develop pneumonia, septicemia, which can lead to occasion...

    Authors: Ruichang Chen, Hongqi Shang, Xiangyun Niu, Jin Huang, Yongqiang Miao, Zhou Sha, Liting Qin, He Huang, Duo Peng and Ruiliang Zhu

    Citation: BMC Veterinary Research 2021 17:107

    Content type: Research article

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  27. Strongylid nematode infections may negatively affect both animal health and welfare, with deleterious consequences for livestock productivity. Many farmers in recent decades have relied on anthelmintics as the...

    Authors: Jaroslav Vadlejch, Iveta Angela Kyriánová, Marián Várady and Johannes Charlier

    Citation: BMC Veterinary Research 2021 17:106

    Content type: Research article

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  28. Alpha-2u globulin nephropathy mainly shows toxicological pathology only in male rats induced by certain chemicals and drugs, such as levamisole (antiparasitic and anticancer drugs). Streptozotocin (STZ) is als...

    Authors: Kanchana Kengkoom, Wannee Angkhasirisap, Tapanee Kanjanapruthipong, Rongdej Tungtrakanpoung, Khwanchanok Tuentam, Naphatson Phansom and Sumate Ampawong

    Citation: BMC Veterinary Research 2021 17:105

    Content type: Research article

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  29. Domestic cats rarely develop hepatocellular carcinoma. The reason for the low prevalence is unknown. Reductions in hepatocellular ploidy have been associated with hepatic carcinogenesis. Recent work in mice ha...

    Authors: Jacqueline Post, Ingeborg M. Langohr, Cynthia R.L. Webster, Peter Mottram, Chin-Chi Liu and Andrea Johnston

    Citation: BMC Veterinary Research 2021 17:104

    Content type: Research article

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  30. Status epilepticus (SE) or prolonged epileptic seizure activity is a common neurological emergency with a high mortality rate and, if left untreated, can lead to irreversible cerebral damage and systemic compl...

    Authors: Marios Charalambous, Holger A. Volk, Luc Van Ham and Sofie F. M. Bhatti

    Citation: BMC Veterinary Research 2021 17:103

    Content type: Review

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  31. In free-ranging reptile populations, bacterial, fungal, viral and parasitic pathogens may affect hosts through impairment in movements, thermoregulation, reproduction, survival, and population dynamics. The sp...

    Authors: Livio Galosi, Anna Rita Attili, Stefania Perrucci, Francesco C. Origgi, Adolfo Maria Tambella, Giacomo Rossi, Vincenzo Cuteri, Maira Napoleoni, Nicholas Aconiti Mandolini, Gianni Perugini and Victor J. T. Loehr

    Citation: BMC Veterinary Research 2021 17:102

    Content type: Research article

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  32. Magnetic resonance imaging (MRI) is the most versatile and informative imaging modality for the diagnosis of locomotor injuries in many animal species; however, veterinary literature describing the MRI of the ...

    Authors: Zakriya Ali Al Mohamad, Usama Hagag, Mohamed Gomaa Tawfiek and Ayman El Nahas

    Citation: BMC Veterinary Research 2021 17:101

    Content type: Research article

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  33. Chronic intermittent or persistent diarrhoea is a common condition in dogs and may be a reflex of gastrointestinal or non-gastrointestinal disorders. Besides diarrhoea, many athletes experience other gastroint...

    Authors: J. C. Alves, A. Santos, P. Jorge and A. Pitães

    Citation: BMC Veterinary Research 2021 17:100

    Content type: Research article

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  34. The horses’ backs are particularly exposed to overload and injuries due to direct contact with the saddle and the influence of e.g. the rider’s body weight. The maximal load for a horse’s back during riding ha...

    Authors: Malgorzata Masko, Marta Borowska, Malgorzata Domino, Tomasz Jasinski, Lukasz Zdrojkowski and Zdzislaw Gajewski

    Citation: BMC Veterinary Research 2021 17:99

    Content type: Research article

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  35. Ménétrier-like disease is a rare hypertrophic canine gastropathy, reported in only seven dogs. Clinical signs are vomiting, anorexia and weight loss. Macroscopically, giant cerebriform gastric mucosal folds ar...

    Authors: E. Lagerstedt, T. Spillmann, N. Airas, L. Solano-Gallego and S. Kilpinen

    Citation: BMC Veterinary Research 2021 17:98

    Content type: Case Report

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  36. Lipopolysaccharides (LPS) derived from gram-negative bacterial are often regarded as primary inducer of bovine mammary inflammation. This study evaluated the biological response of metformin activated AMPK sig...

    Authors: Tianle Xu, Xinyue Wu, Xubin Lu, Yusheng Liang, Yongjiang Mao, Juan J. Loor and Zhangping Yang

    Citation: BMC Veterinary Research 2021 17:97

    Content type: Research article

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  37. Mesenchymal stem cells (MSCs) have generated a great amount of interest in recent years as a novel therapeutic application for improving the quality of pet life and helping them free from painful conditions an...

    Authors: Huina Luo, Dongsheng Li, Zhisheng Chen, Bingyun Wang and Shengfeng Chen

    Citation: BMC Veterinary Research 2021 17:96

    Content type: Research article

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  38. Brucellosis is a contagious zoonotic disease of great public health and economic significance especially in developing countries. The disease affects humans and several species of livestock and wildlife. Studi...

    Authors: Robert Aruho, Ewan T. MacLeod, Leonard Manirakiza and Innocent B. Rwego

    Citation: BMC Veterinary Research 2021 17:95

    Content type: Research article

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  39. Trichinellosis, caused by Trichinella spiralis, is a serious foodborne parasitic zoonosis. Tibetan pig is an infrequent, endemic plateau pig species, mainly distributed in Tibet Plateau, China. Because of the fre...

    Authors: Li Tingting, Li Wenhui, Zhang Nianzhang, Qu Zigang, John A Ohiolei, Li Li, Yan Hongbin, Jia Wanzhong and Fu Baoquan

    Citation: BMC Veterinary Research 2021 17:94

    Content type: Research article

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  40. Animal vaccination is an important way to stop the spread of diseases causing immense damage to livestock and economic losses and the potential transmission to humans. Therefore effective method for vaccine pr...

    Authors: Halima Rhazi, Najete Safini, Karima Mikou, Meryeme Alhyane, Khalid Omari Tadlaoui, Xiangliang Lin, Nandini P. Venkatesan and Mehdi Elharrak

    Citation: BMC Veterinary Research 2021 17:93

    Content type: Research article

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  41. Between February and April 2016, a slight increase in mortality was observed in a colony consisting of 400 captive Seba’s short-tailed bats (Carollia perspicillata). These animals cohabited with other nocturnal a...

    Authors: K. Hahn, I. B. Veiga, M. Schediwy, D. Wiederkehr, M. Meniri, M. Schneeberger, P. Rüegg-van den Broek, C. Gurtner, N. J. Fasel, S. Kittl, M. Fredriksson-Ahomaa, S. Schmitt and N. Stokar-Regenscheit

    Citation: BMC Veterinary Research 2021 17:92

    Content type: Research article

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  42. Ticks transmit several diseases that result in high morbidity and mortality in livestock. Tick-borne diseases are an economic burden that negatively affect livestock production, cost countries billions of doll...

    Authors: Munyaradzi Davis Shekede, Silvester Maravanyika Chikerema, Moregood Spargo, Isaiah Gwitira, Samuel Kusangaya, Aldridge Nyasha Mazhindu and Daud Nyosi Ndhlovu

    Citation: BMC Veterinary Research 2021 17:91

    Content type: Research article

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  43. While a necessary step toward enhancing rigor and reproducibility of veterinary clinical trials conducted on the translational spectrum includes understanding the current state of the field, no broad assessmen...

    Authors: Sarah A. Moore, Angela McCleary-Wheeler, Joan R Coates, Natasha Olby and Cheryl London

    Citation: BMC Veterinary Research 2021 17:90

    Content type: Guidelines

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  44. Prior studies have suggested that pimobendan is associated with several positive effects in cats, including improved survival in cats with congestive heart failure and improved left atrial function in research...

    Authors: Maureen S. Oldach, Yu Ueda, Eric S. Ontiveros, Samantha L. Fousse, Lance C. Visser and Joshua A. Stern

    Citation: BMC Veterinary Research 2021 17:89

    Content type: Research article

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  45. Porcine reproductive and respiratory syndrome (PRRS) is a threat to pig production worldwide. Our objective was to understand mechanisms of persistence of PRRS virus (PRRSV) in tonsil. Transcriptome data from ...

    Authors: Qian Dong, Joan K. Lunney, Kyu-Sang Lim, Yet Nguyen, Andrew S. Hess, Hamid Beiki, Raymond R. R. Rowland, Kristen Walker, James M. Reecy, Christopher K. Tuggle and Jack C. M. Dekkers

    Citation: BMC Veterinary Research 2021 17:88

    Content type: Research article

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  46. Bovine Viral Diarrhea virus (BVDV) is one of important diseases of cattle worldwide causing economic losses to the cattle industry primarily due to increased premature culling and decreased reproductive perfor...

    Authors: Erdachew Yitagesu, Wendi Jackson, Nigatu Kebede, Woutrina Smith and Tsegaw Fentie

    Citation: BMC Veterinary Research 2021 17:87

    Content type: Research article

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  47. The discovery of the superbug mcr-1-positive Escherichia coli (MCRPEC) has drew greet attention. Swine-origin multi-drug resistant MCRPEC has been a potential threat to public health and safety. However, there we...

    Authors: Jingzhi Yuan, Xiaoye Wang, Dali Shi, Qiang Ge, Xingxing Song, Wen Hu, Deyuan Wei, Chenling Ge, Xun Li and Chuanhuo Hu

    Citation: BMC Veterinary Research 2021 17:86

    Content type: Research article

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  48. Lymphocytic neoplasms with frequent reactive lymphocytes are uncommonly reported in dogs, and can pose a diagnostic challenge. Different diagnostic modalities such as cytology, flow cytometry, histopathology, ...

    Authors: Gary Kwok Cheong Lee, Dorothee Bienzle, Stefan Matthias Keller, Mei-Hua Hwang, Nikos Darzentas, Haiyang Chang, Emily Rätsep, Rebecca Egan and Janet Beeler-Marfisi

    Citation: BMC Veterinary Research 2021 17:85

    Content type: Case Report

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  49. Osteosarcoma is a malignant mesenchymal bone tumor. Although it is a common tumor in the appendicular skeleton of dogs and cats, it is rarely reported in birds. Retroviruses are usually associated with solid t...

    Authors: Jefferson Bruno Soares Oliveira, Ayisa Rodrigues de Oliveira, Daniel Oliveira dos Santos, Thaynara Parente de Carvalho, Larissa Giannini Alves Moreira, Herlandes Penha Tinoco, Carlyle Mendes Coelho, Hannah Luiza Gonsalves Coelho, Maria Clara de Paiva Zucherato, Sandra Yuliet Marín-Gómez, Camila Siqueira Costa, Nelson R. S. Martins and Renato Lima Santos

    Citation: BMC Veterinary Research 2021 17:84

    Content type: Case Report

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  50. Respiratory diseases are among the most important factors affecting swine farm productivity in Canada. The objectives of this study were to investigate antibody responses to porcine reproductive and respirator...

    Authors: Elana Raaphorst, Abdolvahab Farzan, Robert M. Friendship and Brandon N. Lillie

    Citation: BMC Veterinary Research 2021 17:82

    Content type: Research article

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