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  1. Content type: Research article

    Incubation period, disease progression, pathology and clinical presentation of classical scrapie in sheep are highly dependent on PRNP genotype, time and route of inoculation and prion strain. Our experimental mo...

    Authors: Siv Meling, Kerstin Skovgaard, Kjetil Bårdsen, Peter Mikael Helweg Heegaard and Martha J. Ulvund

    Citation: BMC Veterinary Research 2018 14:281

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  2. Content type: Research article

    Currently, little is known about the effect of sodium butyrate (NaB) on oxidative stress following grain-induced sub-acute ruminal acidosis in dairy goats. In the present study, 18 lactating dairy goats implan...

    Authors: Nana Ma, Juma Ahamed Abaker, Muhammad Shahid Bilal, Hongyu Dai and Xiangzhen Shen

    Citation: BMC Veterinary Research 2018 14:275

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  3. Content type: Research article

    The role of bats as reservoirs of zoonotic agents, especially pathogenic bacteria such as Bartonella and Coxiella, has been discussed around the world. Recent studies have identified bats as potential hosts of...

    Authors: Michelle Santos Ferreira, Alexandro Guterres, Tatiana Rozental, Roberto Leonan Morim Novaes, Emmanuel Messias Vilar, Renata Carvalho de Oliveira, Jorlan Fernandes, Danielle Forneas, Adonai Alvino Junior, Martha Lima Brandão, José Luis Passos Cordeiro, Martín Roberto Del Valle Alvarez, Sergio Luiz Althoff, Ricardo Moratelli, Pedro Cordeiro-Estrela, Rui Cerqueira da Silva…

    Citation: BMC Veterinary Research 2018 14:279

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  4. Content type: Research article

    Simbu serogroup viruses of the Orthobunyavirus genus (Family Peribunyaviridae) include teratogenic pathogens that cause severe economic losses, abortions, stillbirths and congenital abnormalities in ruminants wor...

    Authors: Daniel Oluwayelu, Kerstin Wernike, Adebowale Adebiyi, Simeon Cadmus and Martin Beer

    Citation: BMC Veterinary Research 2018 14:277

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  5. Content type: Research article

    Rabies is the only known zoonotic disease of bat origin in Europe. The disease is caused by species belonging to the genus Lyssavirus. Five Lyssavirus species, i.e., European bat lyssavirus (EBLV)-1, EBLV-2, Boke...

    Authors: Ivana Šimić, Ivana Lojkić, Nina Krešić, Florence Cliquet, Evelyne Picard-Meyer, Marine Wasniewski, Anđela Ćukušić, Vida Zrnčić and Tomislav Bedeković

    Citation: BMC Veterinary Research 2018 14:274

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  6. Content type: Research article

    Bovine tuberculosis (bTB) is a zoonotic disease of cattle caused by Mycobacterium bovis, widespread in England and Wales. It has high incidence towards the South West of England and Wales, with much lower inciden...

    Authors: Colin P. D. Birch, Ashley Goddard and Oliver Tearne

    Citation: BMC Veterinary Research 2018 14:273

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  7. Content type: Research article

    Timely diagnosis of influenza A virus infections is critical for outbreak control. Due to their rapidity and other logistical advantages, lateral flow immunoassays can support influenza A virus surveillance pr...

    Authors: Amos Ssematimba, Sasidhar Malladi, Peter J. Bonney, Cristian Flores-Figueroa, Jeannette Muñoz-Aguayo, David A. Halvorson and Carol J. Cardona

    Citation: BMC Veterinary Research 2018 14:265

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  8. Content type: Research article

    Recently, mammalian orthoreoviruses (MRVs) were detected for the first time in European bats, and the closely related strain SI-MRV01 was isolated from a child with severe diarrhoea in Slovenia. Genetically si...

    Authors: Tina Naglič, Danijela Rihtarič, Peter Hostnik, Nataša Toplak, Simon Koren, Urška Kuhar, Urška Jamnikar-Ciglenečki, Denis Kutnjak and Andrej Steyer

    Citation: BMC Veterinary Research 2018 14:264

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  9. Content type: Research article

    Effective treatment options for inoperable, metastatic, or recurrent canine pheochromocytomas are lacking. In humans, specific germline mutations exist that drive the development of pheochromocytomas. Pharmace...

    Authors: Margaret L. Musser, Kathryn L. Taikowski, Chad M. Johannes and Philip J. Bergman

    Citation: BMC Veterinary Research 2018 14:272

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  10. Content type: Research article

    The fluorescein clearance test (FCT) provides insight into the tear film dynamics. The purpose of this study was to describe an inexpensive and practical method for assessing FCT in dogs, using photography and...

    Authors: Arianne Pontes Oriá, Miriam Flores Rebouças, Emanoel Martins Filho, Francisco de Assis Dórea Neto, Ana Cláudia Raposo and Lionel Sebbag

    Citation: BMC Veterinary Research 2018 14:269

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    The Correction to this article has been published in BMC Veterinary Research 2018 14:305

  11. Content type: Research article

    African swine fever virus (ASFV) is the etiological agent of African swine fever (ASF), a re-expanding devastating and highly lethal hemorrhagic viral disease. microRNAs (miRNAs) are a new class of small non-c...

    Authors: Fernando Núñez-Hernández, Gonzalo Vera, Armand Sánchez, Fernando Rodríguez and José I. Núñez

    Citation: BMC Veterinary Research 2018 14:268

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  12. Content type: Methodology article

    The presence of cranial tibial subluxation can aid in the detection of joint instability as a result of CrCL injury. Detection of cranial tibial subluxation has been described using the tibial compression test...

    Authors: Katrina A. Castaneda, Caleb C. Hudson and Brian S. Beale

    Citation: BMC Veterinary Research 2018 14:270

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  13. Content type: Research article

    Rift Valley fever (RVF) is classified as viral hemorrhagic fever and is endemic in East and West Africa. RVF is caused by an arthropod borne virus (RVFV); the disease is zoonotic and affects human, animal heal...

    Authors: Ngabo Herbert Budasha, Jean-Paul Gonzalez, Tesfaalem Tekleghiorghis Sebhatu and Ezama Arnold

    Citation: BMC Veterinary Research 2018 14:271

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  14. Content type: Research article

    Sarcoids are the mostcommon skin tumors in horses, characterized by rare regression, invasiveness and high recurrence following surgical intervention and Delta Papillomaviruses are widely recognized as the cau...

    Authors: Manuela Martano, Karen Power, Brunella Restucci, Ilaria Pagano, Gennaro Altamura, Giuseppe Borzacchiello and Paola Maiolino

    Citation: BMC Veterinary Research 2018 14:266

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  15. Content type: Research article

    Muscovy duck parvovirus (MDPV) causes high mortality and morbidity in Muscovy ducks, with the pathogenesis of the virus still unknown in many respects. Specific MDPV detection is often rife with false positive...

    Authors: Chunhe Wan, Cuiteng Chen, Longfei Cheng, Hongmei Chen, Qiuling Fu, Shaohua Shi, Guanghua Fu, Rongchang Liu and Yu Huang

    Citation: BMC Veterinary Research 2018 14:267

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  16. Content type: Research article

    The generation of recombinant proteins for commercialisation must be cost-effective. Despite the cost-effective production of recombinant feline interferon (rFeIFN) by a baculovirus expression system, this rFe...

    Authors: Sachi Minagawa, Yuzuru Nakaso, Masahiro Tomita, Takenori Igarashi, Yoshio Miura, Hideyo Yasuda and Satoshi Sekiguchi

    Citation: BMC Veterinary Research 2018 14:260

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  17. Content type: Research article

    Treatment of infected otitis externa (OE) relies on the topical application of specific formulations that most often contain an antibiotic, an antifungal and a glucocorticoid. This study is to report the resul...

    Authors: S. L. Forster, T. Real, K. P. Doucette and S. B. King

    Citation: BMC Veterinary Research 2018 14:262

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  18. Content type: Research article

    Commensal bacterial and fungal flora of the conjunctival sac has been described in horses and other animals. The identification of commensal flora of the conjunctival sac may aid in the diagnosis of ocular inf...

    Authors: A. Zak, N. Siwinska, M. Slowikowska, H. Borowicz, K. Ploneczka – Janeczko, P. Chorbinski and A. Niedzwiedz

    Citation: BMC Veterinary Research 2018 14:261

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  19. Content type: Research article

    Mechanical interactions between hard floorings and the sole of bovine claws can be reasonable to cause traumatic claw lesions. In this ex vivo study, the direct kinetic impact of concrete and three types of ru...

    Authors: Benjamin Oehme, S. M. Geiger, S. Grund, K. Hainke, J. Munzel and C. K. W. Mülling

    Citation: BMC Veterinary Research 2018 14:259

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  20. Content type: Methodology article

    Foot-and-mouth disease (FMD), which is caused by foot-and-mouth disease virus (FMDV), is a highly contagious tansboundary disease of cloven-hoofed animals and causes devastating economic damages. Accurate, rap...

    Authors: Libing Liu, Jinfeng Wang, Ruoxi Zhang, Mi Lin, Ruihan Shi, Qingan Han, Jianchang Wang and Wanzhe Yuan

    Citation: BMC Veterinary Research 2018 14:263

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  21. Content type: Research article

    Inexpensive and convenient diagnostic tests for use in clinical work and for the surveillance of infection with Mycoplasma bovis are in demand. The objective of this longitudinal field study was to gain knowledge...

    Authors: Mette Bisgaard Petersen, Nadeeka K. Wawegama, Matthew Denwood, Philip F. Markham, Glenn F. Browning and Liza Rosenbaum Nielsen

    Citation: BMC Veterinary Research 2018 14:258

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  22. Content type: Research article

    Salmonella is a major zoonotic food-borne pathogen that persists on poultry farms, and animals undergo reinfection with endemic strains. The present study aimed to investigate the characteristics and disseminatio...

    Authors: Ke Shang, Bai Wei and Min Kang

    Citation: BMC Veterinary Research 2018 14:257

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  23. Content type: Research article

    A direct contact transmission challenge model was used to simulate natural foot-and-mouth disease virus (FMDV) spread from FMDV A24/Cruzeiro/BRA/55 infected ‘seeder’ steers to naïve or vaccinated steers previo...

    Authors: John G. Neilan, Christopher Schutta, José Barrera, Melia Pisano, Laszlo Zsak, Ethan Hartwig, Max V. Rasmussen, Barbara J. Kamicker, Damodar Ettyreddy, Douglas E. Brough, Bryan T. Butman and David A. Brake

    Citation: BMC Veterinary Research 2018 14:254

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  24. Content type: Methodology article

    Ovine footrot is a highly contagious bacterial disease of sheep, costing the Australian sheep industry millions of dollars annually. Dichelobacter nodosus, the causative agent of footrot, is a gram-negative anaer...

    Authors: Nickala Best, Lucas Zanandrez, Jacek Gwozdz, Eckard Klien, Nicky Buller, Robert Suter, Grant Rawlin and Travis Beddoe

    Citation: BMC Veterinary Research 2018 14:252

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  25. Content type: Research article

    Duck Enteritis Virus (DEV), belonging to the α-herpesvirus subfamily, is a linear double-stranded DNA virus. Glycoprotein H and L (gH and gL), encoded by UL22 and UL1, are conserved in the family of herpesviru...

    Authors: Daishen Feng, Min Cui, Renyong Jia, Siyang Liu, Mingshu Wang, Dekang Zhu, Shun Chen, Mafeng Liu, Xinxin Zhao, Yin Wu, Qiao Yang, Zhongqiong Yin and Anchun Cheng

    Citation: BMC Veterinary Research 2018 14:255

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  26. Content type: Research article

    Candida spp. is the vital pathogen involved in mycotic mastitis of cows. However the epidemiology and infection of Candida species in mycotic mastitis of cow in Ningxia province of China has not been explored. In...

    Authors: Jun Du, Xiaoyu Wang, Huixia Luo, Yujiong Wang, Xiaoming Liu and Xuezhang Zhou

    Citation: BMC Veterinary Research 2018 14:251

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  27. Content type: Research article

    Salivary alpha-amylase (sAA) is considered a non-invasive biomarker of acute stress that can be evaluated by changes in activity and concentration, and also by changes in its isoforms, although this last way o...

    Authors: María Dolores Contreras-Aguilar, Damián Escribano, Silvia Martínez-Subiela, Silvia Martínez-Miró, Jose Joaquín Cerón and Fernando Tecles

    Citation: BMC Veterinary Research 2018 14:256

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  28. Content type: Research article

    Foot-and-mouth disease (FMD) is an acute viral disease of cloven-hoofed animals with high economic impact. FMD remains endemic in Iran particularly in the livestock-dense province of Khorasan Razavi in northea...

    Authors: Kayhan Ilbeigi, Saied Bokaie, Sina Aghasharif, Ricardo J. Soares Magalhães and Mohamad Rashtibaf

    Citation: BMC Veterinary Research 2018 14:253

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  29. Content type: Research article

    In the last 20 years, Cetacean Morbillivirus (CeMV) has been responsible for many die-offs in marine mammals worldwide, as clearly exemplified by the three dolphin morbillivirus (DMV) epizootics of 1990–1992, ...

    Authors: Consuelo Rubio-Guerri, M. Ángeles Jiménez, Mar Melero, Josué Díaz-Delgado, Eva Sierra, Manuel Arbelo, Edwige N. Bellière, Jose L. Crespo-Picazo, Daniel García-Párraga, Fernando Esperón and Jose M. Sánchez-Vizcaíno

    Citation: BMC Veterinary Research 2018 14:248

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  30. Content type: Research article

    Selenium (Se) and vitamin E (Vit E) can act synergistically and affect biological processes, mainly antioxidant and immunity. The use of excess dietary Vit E and Se in animals’ feed could enhance immune respon...

    Authors: A. M. Dalia, T. C. Loh, A. Q. Sazili, M. F. Jahromi and A. A. Samsudin

    Citation: BMC Veterinary Research 2018 14:249

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  31. Content type: Research article

    Chemotherapeutic options for the treatment of canine lymphoma have not changed in several decades necessitating the identification of new therapeutics to improve patient outcome. KPT-335 (verdinexor) is a nove...

    Authors: Abbey R. Sadowski, Heather L. Gardner, Antonella Borgatti, Heather Wilson, David M. Vail, Joshua Lachowicz, Christina Manley, Avenelle Turner, Mary K. Klein, Angharad Waite, Alexandra Sahora and Cheryl A. London

    Citation: BMC Veterinary Research 2018 14:250

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  32. Content type: Research article

    Staphylococcus aureus is a contagious, opportunistic pathogen that causes clinical or subclinical mastitis in dairy cattle. The genetic background and antimicrobial resistance of isolates from Ethiopian dairy far...

    Authors: S. A. Mekonnen, T. J. G. M. Lam, J. Hoekstra, V. P. M. G. Rutten, T. S. Tessema, E. M. Broens, A. E. Riesebos, M. P. Spaninks and G. Koop

    Citation: BMC Veterinary Research 2018 14:246

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  33. Content type: Research article

    Endothelial progenitor cells (EPCs) contribute to neovascularization and vascular repair in vivo and are attractive for clinical use in ischemic disease. Tracking of stem and progenitor cells is essential to d...

    Authors: Randolph L. Winter, Wen J. Seeto, Yuan Tian, Fred J. Caldwell, Elizabeth A. Lipke and Anne A. Wooldridge

    Citation: BMC Veterinary Research 2018 14:247

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  34. Content type: Research article

    Equine herpesvirus type 1 (EHV-1) induces respiratory infection, abortion, and neurologic disease with significant impact. Virulence factors contributing to infection and immune evasion are of particular inter...

    Authors: Christiane L. Schnabel, Christine L. Wimer, Gillian Perkins, Susanna Babasyan, Heather Freer, Christina Watts, Alicia Rollins, Nikolaus Osterrieder and Bettina Wagner

    Citation: BMC Veterinary Research 2018 14:245

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  35. Content type: Research article

    Pasteurella multocida type A (PmA) is considered a secondary agent of pneumonia in pigs. The role of PmA as a primary pathogen was investigated by challenging pigs with eight field strains isolated from pneumonia...

    Authors: João Xavier de Oliveira Filho, Marcos Antônio Zanella Morés, Raquel Rebellato, Jalusa Deon Kich, Maurício Egidio Cantão, Catia Silene Klein, Roberto Maurício Carvalho Guedes, Arlei Coldebella, David Emílio Santos Neves de Barcellos and Nelson Morés

    Citation: BMC Veterinary Research 2018 14:244

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  36. Content type: Methodology article

    As the major causative agent of swine viral diarrhea, porcine epidemic diarrhea virus (PEDV) has caused massive losses to the economies of swine raising countries. Accordingly, the serological detection of cor...

    Authors: Huixing Lin, Hong Zhou, Lu Gao, Bin Li, Kongwang He and Hongjie Fan

    Citation: BMC Veterinary Research 2018 14:243

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  37. Content type: Research article

    This study aimed at assessing the effectiveness and safety of repeated administrations of allogeneic bone marrow-derived mesenchymal stem cells (BM-MSCs) primed with tumor necrosis factor (TNF)-α and interfero...

    Authors: Laura Barrachina, Ana Rosa Remacha, Antonio Romero, Arantza Vitoria, Jorge Albareda, Marta Prades, Mercedes Roca, Pilar Zaragoza, Francisco José Vázquez and Clementina Rodellar

    Citation: BMC Veterinary Research 2018 14:241

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  38. Content type: Research article

    Porcine reproductive and respiratory syndrome (PRRS) is a severe disease, causing great economic losses to the pig industry. The causative agent, porcine reproductive and respiratory syndrome virus (PRRSV) is ...

    Authors: Weijie Bai, Zhijia Wang, Pu Sun, Jing Zhang, Huifang Bao, Yimei Cao, Yanyan Chang, Zaixin Liu, Dong Li and Zengjun Lu

    Citation: BMC Veterinary Research 2018 14:240

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  39. Content type: Research article

    Robenacoxib is a non-steroidal anti-inflammatory drug available for canine and feline use for the control of pain and inflammation marketed as Onsior™. The aim of this target animal safety study was to evaluat...

    Authors: Céline E. Toutain, Patrick Brossard, Stephen B. King and Rainer Helbig

    Citation: BMC Veterinary Research 2018 14:242

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  40. Content type: Research article

    Peyer’s patches (PPs) can be considered as the immune site of the intestine. Within PPs, Dendritic cells (DCs) can uptake antigens from the gut lumen by extending dendrites into epithelium, and process it and ...

    Authors: Chen Yuan, En Zhang, Lulu Huang, Jialu Wang and Qian Yang

    Citation: BMC Veterinary Research 2018 14:239

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    The Correction to this article has been published in BMC Veterinary Research 2018 14:303

  41. Content type: Guidelines

    For decades, the efficacy of interventions in clinical trials enrolling dogs with atopic dermatitis (AD) relied on heterogeneous evaluations of skin lesions and pruritus using unvalidated tools. Although some ...

    Authors: Thierry Olivry, Emmanuel Bensignor, Claude Favrot, Craig E. Griffin, Peter B. Hill, Ralf S. Mueller, Jon D. Plant and Hywel C. Williams

    Citation: BMC Veterinary Research 2018 14:238

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  42. Content type: Research article

    Apoptosis plays an important role in the regulation of healthy tissue growth and development as well as in controlling the maintenance of homeostasis in exercising muscles. During an intensive physical effort,...

    Authors: K. Ropka-Molik, M. Stefaniuk-Szmukier, K. Piórkowska, T. Szmatoła and M. Bugno-Poniewierska

    Citation: BMC Veterinary Research 2018 14:237

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  43. Content type: Research article

    During peripartum period, dairy cows are highly susceptible to energy metabolism disorders such as fatty liver and ketosis. Angiopoietin-like protein 4 (ANGPTL4) and fibroblast growth factor 21 (FGF21), known ...

    Authors: Jianguo Wang, Xiaoyan Zhu, Guanghui She, Yezi Kong, Yazhou Guo, Zhe Wang, Guowen Liu and Baoyu Zhao

    Citation: BMC Veterinary Research 2018 14:236

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  44. Content type: Case Report

    Malignant fibrous histiocytoma has been uncommonly described in dogs. Several extranasal neoplasias have been reported to result hypertensive epistaxis. There are, however, no published case reports of extrana...

    Authors: Jung-Hyun Kim, Hee-Jin Kim, Sung-Jun Lee and Hun-Young Yoon

    Citation: BMC Veterinary Research 2018 14:235

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  45. Content type: Research article

    Fatness is an unwanted side effect of genetic selection in broiler chickens. In this study, we introduce mountain celery powder as a feed supplement to suppress lipogenesis and improve antioxidant status in br...

    Authors: Behnam Ahmadipour, Hossein Hassanpour and Fariborz Khajali

    Citation: BMC Veterinary Research 2018 14:234

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  46. Content type: Research article

    Canine breeds may be considered good animal models for the study of genetic predisposition to cancer, as they represent genetic clusters. From epidemiologic and case collection studies it emerges that some bre...

    Authors: Stefano Comazzi, Stefano Marelli, Marzia Cozzi, Rita Rizzi, Riccardo Finotello, Joaquim Henriques, Josep Pastor, Frederique Ponce, Carla Rohrer-Bley, Barbara C. Rütgen and Erik Teske

    Citation: BMC Veterinary Research 2018 14:232

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  47. Content type: Research article

    Cranial cruciate ligament rupture is the most frequent orthopedic disorder in human and animals. An array of surgical techniques have been described to stabilize the stifle joint in dogs, including intraarticu...

    Authors: Yauheni Zhalniarovich, Marta Mieszkowska, Paulina Przyborowska-Zhalniarovich, Joanna Głodek, Andrzej Sobolewski, Grzegorz Waluś and Zbigniew Adamiak

    Citation: BMC Veterinary Research 2018 14:231

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