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  1. Content type: Research article

    Porcine circovirus 2 (PCV2) is the causative agent of porcine circovirus-associated diseases (PCVADs). The infection of PCV2 is widespread and has serious consequence, thereby causing significant economic loss...

    Authors: Yi Hu, Xiong Cai, Yang Zhan, Xiaomin Yuan, Tanbin Liu, Lei Tan, Yalan Li, Lijie Zhang, Lingchen Yang, Wei Liu, Zhibang Deng, Naidong Wang, Yi Yang, Shiyin Guo and Aibing Wang

    Citation: BMC Veterinary Research 2019 15:248

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  2. Content type: Research article

    Recent studies have hypothesized that circulation of classical swine fever virus (CSFV) variants when the immunity induced by the vaccine is not sterilizing might favour viral persistence. Likewise, in additio...

    Authors: Liani Coronado, Jose Alejandro Bohórquez, Sara Muñoz-González, Lester Josue Perez, Rosa Rosell, Osvaldo Fonseca, Laiyen Delgado, Carmen Laura Perera, Maria Teresa Frías and Llilianne Ganges

    Citation: BMC Veterinary Research 2019 15:247

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  3. Content type: Research article

    Brucella ovis causes a sexually transmitted, infectious disease of domestic sheep characterized by genital lesions and epididymitis in rams, placentitis and rare abortions in ewes, and neonatal mortality in lambs...

    Authors: Molly Elderbrook, Brant Schumaker, Todd Cornish, Dannele Peck and Kerry Sondgeroth

    Citation: BMC Veterinary Research 2019 15:246

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  4. Content type: Research article

    Functional Toll-like receptor 4 (TLR4) has been characterized in human and murine platelets indicating that platelets play a role in inflammation and hemostasis during sepsis. It is unclear whether canine plat...

    Authors: Ronald H. L. Li, Nghi Nguyen and Fern Tablin

    Citation: BMC Veterinary Research 2019 15:245

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  5. Content type: Research article

    Gastrointestinal microbiota play an important role in animal host immunity, nutrient metabolism, and energy acquisition, and have therefore drawn increasing attentions. This study compared the diversity of the...

    Authors: Xiangwen Chi, Hongmei Gao, Guosheng Wu, Wen Qin, Pengfei Song, Lei Wang, Jiarui Chen, Zhenyuan Cai and Tongzuo Zhang

    Citation: BMC Veterinary Research 2019 15:243

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  6. Content type: Research article

    Urinalysis is a critical diagnostic test which is performed in routine veterinary medicine practice. In this diagnostic test, semiquantitative measurement of urine biochemical substances is carried out using u...

    Authors: Fatemeh Hekmatynia, Neda Eskandarzadeh, Masoud Imani, Mahdieh Rezaei and Mohamad Zamani-Ahmadmahmudi

    Citation: BMC Veterinary Research 2019 15:242

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  7. Content type: Research article

    A major challenge in modern medicine and animal husbandry is the issue of antimicrobial resistance. One approach to solving this potential medical hazard is the selection of farm animals with less susceptibili...

    Authors: A. Heimes, J. Brodhagen, R. Weikard, H. M. Hammon, M. M. Meyerholz, W. Petzl, H. Zerbe, S. Engelmann, M. Schmicke, M. Hoedemaker, H.-J. Schuberth and C. Kühn

    Citation: BMC Veterinary Research 2019 15:241

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    The Correction to this article has been published in BMC Veterinary Research 2019 15:285

  8. Content type: Methodology article

    Vascular access port (VAP) systems are widely used in human medicine to provide long-term venous access. However, in veterinary medicine the use of VAP systems is not common practice and publications on their ...

    Authors: Kiona S. de Nies, Hedwig S. Kruitwagen, Giora van Straten, Leonie W. L. van Bruggen, Joris H. Robben, Baukje A. Schotanus, Ies Akkerdaas and Anne Kummeling

    Citation: BMC Veterinary Research 2019 15:240

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  9. Content type: Research article

    Probiotics are important for pigs to enhance health and intestinal development, which are potential alternative to antibiotics. Many studies have reported the functions of single bacterial strain as probiotic ...

    Authors: Shilan Wang, Bingqian Yao, Hang Gao, Jianjun Zang, Shiyu Tao, Shuai Zhang, Shimeng Huang, Beibei He and Junjun Wang

    Citation: BMC Veterinary Research 2019 15:239

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  10. Content type: Research article

    Mupirocin is one of the few antimicrobials active against methicillin-resistant Staphylococcus aureus (MRSA), and is frequently used for the eradication of MRSA nasal colonisation in humans. Initially, mupirocin ...

    Authors: Magdalena Kizerwetter-Świda, Dorota Chrobak-Chmiel and Magdalena Rzewuska

    Citation: BMC Veterinary Research 2019 15:238

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  11. Content type: Research article

    Exercise testing in conjunction with measurement of cardiac biomarkers NT-proBNP and cTnI is a useful tool for monitoring the effect of treatment on cardiac patients. Administering Pimobendan in dogs with dege...

    Authors: Nayeli Iwanuk, Ingo Nolte, Leona Wall, Maximiliane Sehn, Jonathan Raue, Anna Pilgram, Katja Rumstedt and Jan-Peter Bach

    Citation: BMC Veterinary Research 2019 15:237

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  12. Content type: Research article

    Lumpy skin disease (LSD) is a transboundary cattle disease caused by a Capripoxvirus of the family Poxviridae. In Uganda, documented information on the epidemiology of the disease is rare and there is no nationwi...

    Authors: Sylvester Ochwo, Kimberly VanderWaal, Anna Munsey, Joseph Nkamwesiga, Christian Ndekezi, Elda Auma and Frank N. Mwiine

    Citation: BMC Veterinary Research 2019 15:236

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  13. Content type: Research article

    Enterococcus is an important component of normal flora in human and animals, but in recent years, the pathogenicity of Enterococcus has been confirmed in clinical medicine. More and more animal infections have...

    Authors: Yingjin Chai, Xiaoxiao Gu, Qin Wu, Bingjiao Guo, Yayin Qi, Xiaolan Wang, Xia Zhou, Jie Li, Mengli Han and Fagang Zhong

    Citation: BMC Veterinary Research 2019 15:235

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  14. Content type: Research article

    Enterotoxigenic Escherichia coli K88 (E. coli K88) are considered as a major cause of diarrhea and death in newly weaned piglets. Oral passive immunization with chicken egg yolk immunoglobulins (IgY) have attract...

    Authors: Zhaobin Wang, Jia Li, Jianzhong Li, Yali Li, Lixia Wang, Qingping Wang, Lin Fang, Xueqin Ding, Pengfei Huang, Jia Yin, Yulong Yin and Huansheng Yang

    Citation: BMC Veterinary Research 2019 15:234

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  15. Content type: Research article

    The increasing costs of feed has subsequently increased the costs of production of livestock, thereby decreasing the profit margin of this sector. The utilization of agro-industrial by-products has to some ext...

    Authors: O. A. Saeed, A. Q. Sazili, H. Akit, M. Ebrahimi, A. R. Alimon and A. A. Samsudin

    Citation: BMC Veterinary Research 2019 15:233

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  16. Content type: Research article

    Recently, serotype 4 fowl adenovirus (FAdV-4) has spread widely and caused huge economic loss to poultry industry. However, little is known about the molecular pathogenesis of FAdV-4. Fiber protein is thought ...

    Authors: Hongxia Shao, Yanan Lu, Weikang Wang, Tuofan Li, Jianjun Zhang, Zhimin Wan, Guangchen Liang, Wei Gao, Aijian Qin and Jianqiang Ye

    Citation: BMC Veterinary Research 2019 15:232

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  17. Content type: Research article

    Monitoring systems are essential to detect if the number of cases of a specific disease is rising. Data collected as part of voluntary disease monitoring programs is particularly useful to evaluate if control ...

    Authors: Ana Carolina Lopes Antunes and Dan Jensen

    Citation: BMC Veterinary Research 2019 15:231

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  18. Content type: Research article

    The small ruminant lentiviruses (SRLVs) are a heterogeneous group of viruses that includes caprine arthritis encephalitis virus (CAEV) and Maedi-Visna virus (MVV). SRLVs affect the production and welfare of sh...

    Authors: Silvia Colussi, Rosanna Desiato, Chiara Beltramo, Simone Peletto, Paola Modesto, Maria Grazia Maniaci, Valentina Campia, Antonio Quasso, Sergio Rosati, Luigi Bertolotti, Giuseppe Ru and Pier Luigi Acutis

    Citation: BMC Veterinary Research 2019 15:230

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  19. Content type: Case Report

    Listeria monocytogenes is a ubiquitous Gram-positive bacterium responsible for a severe foodborne disease in humans, and contaminated dairy products can be an important source of infection. Typically, infected da...

    Authors: Maria Filippa Addis, Tiziana Cubeddu, Ylenia Pilicchi, Stefano Rocca and Renata Piccinini

    Citation: BMC Veterinary Research 2019 15:229

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  20. Content type: Case Report

    Thyroid neoplasia is a common endocrine neoplasm in dogs. The boxer is one of the reported breeds predisposed to malignant thyroid neoplasia. However, the association between thyroid neoplasia, malignancy and ...

    Authors: Marie-Pauline Maurin, Dan Davies, Hanne Jahns, Robert E. Shiel and Carmel T. Mooney

    Citation: BMC Veterinary Research 2019 15:228

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  21. Content type: Research article

    Antimicrobial resistance is a worldwide problem causing serious health threats. Escherichia coli is one of the most important bacteria that causes resistance problem. These bacteria produce an enzyme called exten...

    Authors: Romeo S. Gundran, Paul A. Cardenio, Marvin A. Villanueva, Fredelon B. Sison, Carolyn C. Benigno, Kwanchai Kreausukon, Duangporn Pichpol and Veerasak Punyapornwithaya

    Citation: BMC Veterinary Research 2019 15:227

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  22. Content type: Research article

    Canine lobular orbital adenomas are benign tumors that arise from orbital glandular tissue and extend into the orbit, conjunctiva, and third eyelid. Surgical excision is challenging and recurrence rates are hi...

    Authors: Elizabeth A. F. Schaefer, Shirley Chu, Jacqueline W. Pearce, Jeffrey N. Bryan and Brian K. Flesner

    Citation: BMC Veterinary Research 2019 15:226

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  23. Content type: Research article

    Acute ruminal acidosis (ARA) is a metabolic disease of cattle characterized by an aseptic synovitis. ARA is the result of an increased intake of highly fermentable carbohydrates that frequently occurs in dairy...

    Authors: Alejandra I. Hidalgo, María D. Carretta, Pablo Alarcón, Carolina Manosalva, Ananda Müller, Max Navarro, María A. Hidalgo, Thilo Kaehne, Anja Taubert, Carlos R. Hermosilla and Rafael A. Burgos

    Citation: BMC Veterinary Research 2019 15:225

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  24. Content type: Research article

    As a kind of opportunist pathogen, Staphylococcus xylosus (S. xylosus) can cause mastitis. Antibiotics are widely used for treating infected animals and tylosin is a member of such group. Thus, the continuous use...

    Authors: Xin Liu, Jinpeng Wang, Mo Chen, Ruixiang Che, Wenya Ding, Fei Yu, Yonghui Zhou, Wenqiang Cui, Xing Xiaoxu, Bello-Onaghise God’spower and Yanhua Li

    Citation: BMC Veterinary Research 2019 15:224

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  25. Content type: Research article

    The role played by the humoral immune response in animals vaccinated against a mycobacterial disease such as paratuberculosis, is not well understood. Sheep vaccinated against Mycobacterium avium subsp. paratuber...

    Authors: Hannah B. Pooley, Douglas J. Begg, Karren M. Plain, Richard J. Whittington, Auriol C. Purdie and Kumudika de Silva

    Citation: BMC Veterinary Research 2019 15:223

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  26. Content type: Research article

    Inappropriate antimicrobial use (AMU) is a key modifiable factor that leads to the development of antimicrobial resistance (AMR). The objectives of this study were to determine the following among Tennessee be...

    Authors: John E. Ekakoro, Marc Caldwell, Elizabeth B. Strand, Lew Strickland and Chika C. Okafor

    Citation: BMC Veterinary Research 2019 15:222

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  27. Content type: Research article

    During skull ontogenesis, growth centers in the skull base and calvarial bones allow gradual expansion of the cranial vault. Premature growth termination of cranial base synchondroses and/or calvarial sutures ...

    Authors: Daniela Farke, Carsten Staszyk, Klaus Failing, Robert M. Kirberger and Martin J. Schmidt

    Citation: BMC Veterinary Research 2019 15:221

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  28. Content type: Research article

    Canine atopic dermatitis (AD) is a common skin disease. The goal of this study was to evaluate food designed to improve skin barrier function and lower inflammation to reduce pruritus and clinical severity in ...

    Authors: Angela Witzel-Rollins, Maryanne Murphy, Iveta Becvarova, Stephen R. Werre, Marie-Christine Cadiergues and Hein Meyer

    Citation: BMC Veterinary Research 2019 15:220

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  29. Content type: Research article

    Although the poultry sector accounts for a major portion of global antimicrobial consumption, few studies have explored the factors which influence antimicrobial use (AMU) in poultry farms in Europe. We perfor...

    Authors: Cécile J. M. Adam, Nicolas Fortané, Alexandra Coviglio, Léa Delesalle, Christian Ducrot and Mathilde C. Paul

    Citation: BMC Veterinary Research 2019 15:219

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  30. Content type: Research article

    Antimicrobial use (AMU) in livestock is a debated topic, mainly due to the risk of associated development of antimicrobial resistance. There is focus on reducing AMU in the Danish pig production, which account...

    Authors: Amanda Brinch Kruse, Charlotte Sonne Kristensen, Ulrik Lavlund and Helle Stege

    Citation: BMC Veterinary Research 2019 15:218

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  31. Content type: Research article

    Myxosarcomas are known to be classified as soft tissue sarcomas. However, there is limited clinical characterization pertaining specifically to canine cutaneous myxosarcomas in the literature. The objective of...

    Authors: Yoshimi Iwaki, Stephanie Lindley, Annette Smith, Kaitlin M. Curran and Jayme Looper

    Citation: BMC Veterinary Research 2019 15:217

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  32. Content type: Research article

    This study aimed to evaluate the efficacy of anthelmintics in goats raised under mountain farming conditions in northern Italy. On 8 goat farms (n = 143 animals), a faecal egg count reduction (FECR) test was done...

    Authors: C. Lambertz, I. Poulopoulou, K. Wuthijaree and M. Gauly

    Citation: BMC Veterinary Research 2019 15:216

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  33. Content type: Research article

    Leptin has been shown to have various physiological and pathological roles in the canine gallbladder. In this study, we performed pre- and postoperative short-term follow-up analyses to confirm changes in seru...

    Authors: Sungin Lee, Aeri Lee, Oh-kyeong Kweon and Wan Hee Kim

    Citation: BMC Veterinary Research 2019 15:215

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  34. Content type: Research article

    Per- and polyfluoroalkyl substances (PFASs) are environmentally persistent and bioaccumulative chemicals. Immunomodulation is among the most concerning of toxic effects linked with PFAS exposure in mammalian m...

    Authors: Jose M. Castaño-Ortiz, Veerle L. B. Jaspers and Courtney A. Waugh

    Citation: BMC Veterinary Research 2019 15:214

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  35. Content type: Research article

    This study aimed to evaluate the safety and efficacy of reduced-dosage ketoprofen with or without tramadol in dogs. Five healthy dogs receiving standard-dosage ketoprofen (2 mg/kg SC, then 1 mg/kg PO daily) co...

    Authors: Beatriz P. Monteiro, Cedric Lambert, Elena Bianchi, Jean Pierre Genevois, Giulio Soldani and Eric Troncy

    Citation: BMC Veterinary Research 2019 15:213

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  36. Content type: Research article

    Multi-drug resistant bacteria are seen increasingly and there are gaps in our understanding of the complexity of antimicrobial resistance, partially due to a lack of appropriate statistical tools. This hampers...

    Authors: Sonja Hartnack, Terence Odoch, Gilles Kratzer, Reinhard Furrer, Yngvild Wasteson, Trine M. L’Abée-Lund and Eystein Skjerve

    Citation: BMC Veterinary Research 2019 15:212

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  37. Content type: Debate

    Bisphosphonates (BPs) are a family of molecules characterized by two key properties: their ability to bind strongly to bone mineral and their inhibitory effects on mature osteoclasts and thus bone resorption. ...

    Authors: Alexis Mitchell, Ashlee E. Watts, Frank H. Ebetino and Larry J. Suva

    Citation: BMC Veterinary Research 2019 15:211

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  38. Content type: Research article

    Oxyclozanide is an anthelmintic drug that is widely used to treat fasciolosis. However, the pharmacokinetics of oxyclozanide in cattle are not yet clearly understood. The present study was designed to develop a s...

    Authors: Jili Zhang, Yubin Bai, Bing Li, Xuzheng Zhou, Hongfei Si and Jiyu Zhang

    Citation: BMC Veterinary Research 2019 15:210

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  39. Content type: Research article

    While commercial poultry and captive birds are exposed to antimicrobials through direct medication, environmental pollution may result in contamination of wild birds. Fluoroquinolones are commonly used medicat...

    Authors: Hana Hruba, Ehdaa Eltayeb Eltigani Abdelsalam, Nikolay Anisimov, Hana Bandouchova, Barbora Havelkova, Tomas Heger, Miroslava Kanova, Veronika Kovacova, Monika Nemcova, Vladimir Piacek, Jana Sedlackova, Frantisek Vitula and Jiri Pikula

    Citation: BMC Veterinary Research 2019 15:209

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  40. Content type: Research article

    Infectious diseases are an important role obstacle to high productivity in Ugandan cattle production. General disease prevention is particularly important in low-income countries, where veterinary services and...

    Authors: Cecilia Wolff, Salvatory Abigaba and Susanna Sternberg Lewerin

    Citation: BMC Veterinary Research 2019 15:208

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  41. Content type: Research article

    Periodontal disease is the most common oral disease of dogs and has been associated with systemic disease. The purpose of the present study was to determine the extent of periodontal disease in a population of...

    Authors: Corrin Wallis, Ilaria Pesci, Alison Colyer, Lisa Milella, Peter Southerden, Lucy J. Holcombe and Neil Desforges

    Citation: BMC Veterinary Research 2019 15:207

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  42. Content type: Research article

    Antimicrobials are used by poultry farmers in Vietnam as a tool to treat and prevent infectious diseases. We aimed to determine the fraction of disease episodes likely to remain untreated due to the administra...

    Authors: Marc Choisy, Nguyen Van Cuong, Truong Dinh Bao, Bach Tuan Kiet, Bo Ve Hien, Ho Viet Thu, Niwat Chansiripornchai, Erry Setyawan, Guy Thwaites, Jonathan Rushton and Juan Carrique-Mas

    Citation: BMC Veterinary Research 2019 15:206

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  43. Content type: Research article

    Poultry farming is widely practiced by rural households in Vietnam and the vast majority of domestic birds are kept on small household farms. However, smallholder poultry production is constrained by several i...

    Authors: Alexis Delabouglise, Benjamin Nguyen-Van-Yen, Nguyen Thi Le Thanh, Huynh Thi Ai Xuyen, Phung Ngoc Tuyet, Ha Minh Lam and Maciej F. Boni

    Citation: BMC Veterinary Research 2019 15:205

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  44. Content type: Case Report

    Mast cell tumours are the most common cutaneous neoplasms in dogs. Other primary sites include visceral organs, such as the gastrointestinal tract, liver, or spleen, and the oral cavity. Frequent metastatic sites...

    Authors: Juan Carlos Cartagena-Albertus, Antoaneta Moise, Sergio Moya-García, Nora Cámara-Fernández and Jose Alberto Montoya-Alonso

    Citation: BMC Veterinary Research 2019 15:204

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  45. Content type: Research article

    Prostaglandin F2α (PGF2α) is an important component for the physiology of female reproductive processes. In the literature, the data pertaining to the synthesis and action of PGF2α in early embryonic bovine devel...

    Authors: Katarzyna Grycmacher, Dorota Boruszewska, Emilia Sinderewicz, Ilona Kowalczyk-Zięba, Joanna Staszkiewicz-Chodor and Izabela Woclawek-Potocka

    Citation: BMC Veterinary Research 2019 15:203

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  46. Content type: Research article

    Bovine viral diarrhea virus (BVDV) infects various ungulates and causes reproductive failure in infected goats. BVDV has been detected among goats in the Republic of Korea, but the route of transmission remain...

    Authors: Jae-Ku Oem, Du-Gyeong Han and Kyoung-Seong Choi

    Citation: BMC Veterinary Research 2019 15:202

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  47. Content type: Research article

    Joint injury is extremely common in equine athletes and post-traumatic osteoarthritis (PTOA), a progressive and debilitating disease, is estimated to affect 60% of horses in the USA. The limited potential for ...

    Authors: Alexis L. Gale, Renata M. Mammone, Michael E. Dodson, Renata L. Linardi and Kyla F. Ortved

    Citation: BMC Veterinary Research 2019 15:201

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  48. Content type: Research article

    Porcine circovirus 3 (PCV3) is an emerging etiological agent to the swine industry. However, its circulating status and genetic characteristics were still unclear in Henan, central China. Here, 318 porcine ora...

    Authors: Zhenhua Guo, Xiang Li, Ruiguang Deng and Gaiping Zhang

    Citation: BMC Veterinary Research 2019 15:200

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  49. Content type: Research article

    The purpose of the present study was to assess if the exposure to glutamine (Gln), arginine (Arg) or their combination from pregnancy, through the maternal diet, to a post weaning supplemented diet, can stimul...

    Authors: Rebeca Delgado, Rodrigo Abad-Guamán, Nuria Nicodemus, Araceli Diaz-Perales, Javier García, Rosa Carabaño and David Menoyo

    Citation: BMC Veterinary Research 2019 15:199

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  50. Content type: Review

    Paratuberculosis, a chronic disease affecting ruminant livestock, is caused by Mycobacterium avium subsp. paratuberculosis (MAP). It has direct and indirect economic costs, impacts animal welfare and arouses publ...

    Authors: Richard Whittington, Karsten Donat, Maarten F. Weber, David Kelton, Søren Saxmose Nielsen, Suzanne Eisenberg, Norma Arrigoni, Ramon Juste, Jose Luis Sáez, Navneet Dhand, Annalisa Santi, Anita Michel, Herman Barkema, Petr Kralik, Polychronis Kostoulas, Lorna Citer…

    Citation: BMC Veterinary Research 2019 15:198

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