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  1. Ghrelin is a natural ligand of the growth hormone secretagogue receptor (GHS-R). They are often co-expressed in multiple human tumors and related cancer cell lines what can indicate that the ghrelin/GHS-R axis...

    Authors: Kinga Majchrzak, Karol M Pawłowski, Emilia J Orzechowska, Izabella Dolka, Joanna Mucha, Tomasz Motyl and Magdalena Król
    Citation: BMC Veterinary Research 2012 8:170
  2. Mesenchymal stem cells (MSCs) are multipotent stem cells with capacity to differentiate into several mesenchymal lineages. This quality makes MSCs good candidates for use in cell therapy. MSCs can be isolated ...

    Authors: Jaber Lyahyai, Diego R Mediano, Beatriz Ranera, Arianne Sanz, Ana Rosa Remacha, Rosa Bolea, Pilar Zaragoza, Clementina Rodellar and Inmaculada Martín-Burriel
    Citation: BMC Veterinary Research 2012 8:169
  3. Bovine tuberculosis (TB) caused by Mycobacterium bovis is primarily a disease of ruminants, particularly cattle (Bos primigenius) and buffalo (Syncerus caffer), and is endemic in most developing countries. To dat...

    Authors: Adrian Muwonge, Tone B Johansen, Edvardsen Vigdis, Jacques Godfroid, Francisco Olea-Popelka, Demelash Biffa, Eystein Skjerve and Berit Djønne
    Citation: BMC Veterinary Research 2012 8:168
  4. Bovine leukemia virus (BLV) is associated with enzootic bovine leukosis, which is the most common neoplastic disease of cattle. BLV infects cattle worldwide, imposing a severe economic impact on the dairy catt...

    Authors: Mayuko Jimba, Shin-nosuke Takeshima, Hironobu Murakami, Junko Kohara, Naohiko Kobayashi, Tamako Matsuhashi, Takashi Ohmori, Tetsuo Nunoya and Yoko Aida
    Citation: BMC Veterinary Research 2012 8:167
  5. One of the purposes of treatment for dogs with mitral regurgitation (MR) is lowering left atrial pressure (LAP). There has been few study of the amlodipine in dogs with MR and amlodipine’s effect on LAP has no...

    Authors: Shuji Suzuki, Ryuji Fukushima, Taisuke Ishikawa, Yuta Yamamoto, Lina Hamabe, Soomin Kim, Rieko Yoshiyuki, Noboru Machida and Ryou Tanaka
    Citation: BMC Veterinary Research 2012 8:166
  6. The bacterium Coxiella burnetii has caused unprecedented outbreaks of Q fever in the Netherlands between 2007 and 2010. Since 2007, over 4000 human cases have been reported, with 2354 cases in 2009 alone. Dairy g...

    Authors: Arnout de Bruin, Pleunie TW van Alphen, Rozemarijn QJ van der Plaats, Lianne ND de Heer, Chantal BEM Reusken, Bart J van Rotterdam and Ingmar Janse
    Citation: BMC Veterinary Research 2012 8:165
  7. Pregnancy testing in cattle is commonly invasive requiring manual rectal palpation of the reproductive tract that presents risks to the operator and pregnancy. Alternative non-invasive tests have been develope...

    Authors: Gaetano D Gargiulo, Richard W Shephard, Jonathan Tapson, Alistair L McEwan, Paolo Bifulco, Mario Cesarelli, Craig Jin, Ahmed Al-Ani, Ning Wang and André van Schaik
    Citation: BMC Veterinary Research 2012 8:164
  8. The population of dogs and cats passing through rescue shelters may be subject to compromised welfare and increased susceptibility to disease. Little information exists to describe this population, its dynamic...

    Authors: Jenny Stavisky, Marnie L Brennan, Martin Downes and Rachel Dean
    Citation: BMC Veterinary Research 2012 8:163
  9. The conceptual validity of kinetic gait analysis and disability outcome assessment methods has guided their use in the assessment of pain caused by osteoarthritis (OA). No consensus on the best clinical method...

    Authors: Pascale Rialland, Sylvain Bichot, Maxim Moreau, Martin Guillot, Bertrand Lussier, Dominique Gauvin, Johanne Martel-Pelletier, Jean-Pierre Pelletier and Eric Troncy
    Citation: BMC Veterinary Research 2012 8:162
  10. Glucocorticoids have been proven to be effective in the therapy of recurrent airway obstruction (RAO) in horses via systemic as well as local (inhalative) administration. Elective analysis of the effects of th...

    Authors: Maria Fugazzola, Ann-Kristin Barton, Frank Niedorf, Manfred Kietzmann and Bernhard Ohnesorge
    Citation: BMC Veterinary Research 2012 8:160
  11. A common approach to the application of epidemiological models is to determine a single (point estimate) parameterisation using the information available in the literature. However, in many cases there is cons...

    Authors: Ross S Davidson, Iain J McKendrick, Joanna C Wood, Glenn Marion, Alistair Greig, Karen Stevenson, Michael Sharp and Michael R Hutchings
    Citation: BMC Veterinary Research 2012 8:159
  12. Understanding the pathogenesis of the chiari-like malformation in the Cavalier King Charles Spaniel (CKCS) is incomplete, and current hypotheses do not fully explain the development of syringomyelia (SM) in th...

    Authors: Martin Jürgen Schmidt, Nele Ondreka, Maren Sauerbrey, Holger Andreas Volk, Christoph Rummel and Martin Kramer
    Citation: BMC Veterinary Research 2012 8:158
  13. An un-commissioned randomized, double-blinded, placebo controlled clinical study was planned using a deep sea fish oil product for pets. Seventy-seven client-owned dogs with osteoarthritis were randomly assign...

    Authors: Anna Hielm-Björkman, Johanna Roine, Kari Elo, Anu Lappalainen, Jouni Junnila and Outi Laitinen-Vapaavuori
    Citation: BMC Veterinary Research 2012 8:157
  14. There is poor understanding of most aspects of Clostridium perfringens type A as a possible cause of neonatal diarrhea in piglets, and the prevalence and types of C. perfringens present on Ontario swine farms is ...

    Authors: Gloria Chan, Abdolvahab Farzan, Glenn Soltes, Vivian M Nicholson, Yanlong Pei, Robert Friendship and John F Prescott
    Citation: BMC Veterinary Research 2012 8:156
  15. Noroviruses (NoVs) are members of the family Caliciviridae and are emerging enteric pathogens of humans and animals. Some porcine NoVs are genetically similar to human strains and are classified into GII, like mo...

    Authors: Quan Shen, Wen Zhang, Shixing Yang, Zhibiao Yang, Yan Chen, Li Cui, Jianguo Zhu and Xiuguo Hua
    Citation: BMC Veterinary Research 2012 8:155
  16. The allergic test of mallein is one of the most frequently used tests, together with the Complement Fixation Test (CFT), for the diagnosis of glanders in endemic areas. Mallein, a purified protein derivative (...

    Authors: Maurício Baltazar de Carvalho Filho, Rodrigo Mauro Ramos, Antônio Augusto Fonseca Jr, Lívia de Lima Orzil, Mariana Lázaro Sales, Vania Lucia de Assis Santana, Marcilia Maria Alves de Souza, Evandro dos Reis Machado, Paulo Rodrigues Lopes Filho, Rômulo Cerqueira Leite and Jenner Karlisson Pimenta dos Reis
    Citation: BMC Veterinary Research 2012 8:154
  17. Dehorning is a common practice involving calves on dairy operations in the United States. However, less than 20% of producers report using analgesics or anesthetics during dehorning. Administration of a system...

    Authors: Johann F Coetzee, Ruby A Mosher, Butch KuKanich, Ronette Gehring, Brad Robert, J Brandon Reinbold and Brad J White
    Citation: BMC Veterinary Research 2012 8:153
  18. Brachycephalic dogs have unique upper respiratory anatomy with abnormal breathing patterns similar to those in humans with obstructive sleep apnea syndrome (OSAS). The objective of this study was to evaluate t...

    Authors: Marta Planellas, Rafaela Cuenca, Maria-Dolores Tabar, Coralie Bertolani, Cyrill Poncet, Josep M Closa, Juan Lorente, Jose J Cerón and Josep Pastor
    Citation: BMC Veterinary Research 2012 8:152
  19. Abattoir detected pathologies are of crucial importance to both pig production and food safety. Usually, more than one pathology coexist in a pig herd although it often remains unknown how these different path...

    Authors: Manuel J Sanchez-Vazquez, Mirjam Nielen, Sandra A Edwards, George J Gunn and Fraser I Lewis
    Citation: BMC Veterinary Research 2012 8:151
  20. Bone marrow-derived mesenchymal stem cells (BM-MSCs) and adipose tissue-derived mesenchymal stem cells (AT-MSCs) are potential cellular sources of therapeutic stem cells. MSCs are a multipotent population of c...

    Authors: Hiroshi Takemitsu, Dongwei Zhao, Ichiro Yamamoto, Yasuji Harada, Masaki Michishita and Toshiro Arai
    Citation: BMC Veterinary Research 2012 8:150
  21. The uncontrolled presence of African swine fever (ASF) in Russian Federation (RF) poses a serious risk to the whole European Union (EU) pig industry. Although trade of pigs and their products is banned since t...

    Authors: Lina Mur, Beatriz Martínez-López and José Manuel Sánchez-Vizcaíno
    Citation: BMC Veterinary Research 2012 8:149
  22. Bovine tuberculosis (bTB) is a chronic infectious disease mainly caused by Mycobacterium bovis. Although eradication is a priority for the European authorities, bTB remains active or even increasing in many count...

    Authors: Víctor Rodríguez-Prieto, Beatriz Martínez-López, José Ángel Barasona, Pelayo Acevedo, Beatriz Romero, Sabrina Rodriguez-Campos, Christian Gortázar, José Manuel Sánchez-Vizcaíno and Joaquín Vicente
    Citation: BMC Veterinary Research 2012 8:148
  23. Recently, metabolic syndrome (MS) has gained attention in human metabolic medicine given its associations with development of type 2 diabetes mellitus and cardiovascular disease. Canine obesity is associated w...

    Authors: Asta Tvarijonaviciute, Jose J Ceron, Shelley L Holden, Daniel J Cuthbertson, Vincent Biourge, Penelope J Morris and Alexander J German
    Citation: BMC Veterinary Research 2012 8:147
  24. The genetic diversity of Mycoplasma agalactiae (MA) isolates collected in Spain from goats in an area with contagious agalactia (CA) was assessed using a set of validated and new molecular typing methods. Validat...

    Authors: Christian De la Fe, Joaquín Amores, Florence Tardy, Eveline Sagne, Laurent-Xavier Nouvel and Christine Citti
    Citation: BMC Veterinary Research 2012 8:146
  25. Development of a method for long-term labeling of cells is critical to elucidate transplanted cell fate and migration as well as the contribution to tissue regeneration. Silica nanoparticles have been recently...

    Authors: Sei-Myoung Han, Hee-Woo Lee, Dong-Ha Bhang, Kyoung-Won Seo and Hwa-Young Youn
    Citation: BMC Veterinary Research 2012 8:145
  26. This study was carried out to investigate the status of brucellosis in cattle under various management systems in Adamawa, Kaduna and Kano states, northern Nigeria. Using multi-stage sampling, serum samples of...

    Authors: Hassan M Mai, Peter C Irons, Junaidu Kabir and Peter N Thompson
    Citation: BMC Veterinary Research 2012 8:144
  27. Mucosal epithelia, including those of the oviduct, secrete antimicrobial innate immune molecules (AIIMS). These have bactericidal/bacteriostatic functions against a variety of pathogens. Among the AIIMs, sheep...

    Authors: Shiyong Wen, Guifang Cao, Tuya Bao, LanLing Cheng, Haijun Li, Chenguang Du, Yong Tu, Qi Li, Ruizhen Jian and Pengwei Zhao
    Citation: BMC Veterinary Research 2012 8:143
  28. Mesenchymal stem cells (MSCs) derived from bone marrow (BM-MSCs) and adipose tissue (AT-MSCs) are being applied to equine cell therapy. The physiological environment in which MSCs reside is hypoxic and does no...

    Authors: Beatriz Ranera, Ana Rosa Remacha, Samuel Álvarez-Arguedas, Antonio Romero, Francisco José Vázquez, Pilar Zaragoza, Inmaculada Martín-Burriel and Clementina Rodellar
    Citation: BMC Veterinary Research 2012 8:142
  29. Ophthalmic antibiotic therapy in large animals is often used empirically because of the lack of pharmacokinetics studies. The purpose of the study was to determine the pharmacokinetics of topical tobramycin 0....

    Authors: Sarah L Czerwinski, Andrew W Lyon, Brian Skorobohach and Renaud Léguillette
    Citation: BMC Veterinary Research 2012 8:141
  30. Extraintestinal pathogenic Escherichia coli (ExPEC) can cause a variety of infections outside the gastrointestinal tract in humans and animals. Infections due to swine ExPECs have been occurring with increasing f...

    Authors: Yi Ding, Xibiao Tang, Ping Lu, Bin Wu, Zhuofei Xu, Wugang Liu, Ruixuan Zhang, Weicheng Bei, Huanchun Chen and Chen Tan
    Citation: BMC Veterinary Research 2012 8:140
  31. To compare the biomechanical in-vitro characteristics of limited-contact dynamic compression plate (LC-DCP) and locking compression plate (LCP) constructs in an osteotomy gap model of femoral fracture in neona...

    Authors: Mona Hoerdemann, Philippe Gédet, Steven J Ferguson, Carola Sauter-Louis and Karl Nuss
    Citation: BMC Veterinary Research 2012 8:139
  32. The rabbit is a common animal model for ophthalmic research, especially corneal research. Ocular structures grow rapidly during the early stages of life. It is unclear when the rabbit cornea becomes mature and...

    Authors: Andri K Riau, Neil YS Tan, Romesh I Angunawela, Hla M Htoon, Shyam S Chaurasia and Jodhbir S Mehta
    Citation: BMC Veterinary Research 2012 8:138
  33. Lyme disease is a widespread cosmopolitan zoonosis caused by species belonging to the genus Borrelia. It is transmitted from animal reservoir hosts to humans through hard - ticks of genus Ixodes which are vectors...

    Authors: Călin M Gherman, Attila D Sándor, Zsuzsa Kalmár, Mihai Marinov and Andrei D Mihalca
    Citation: BMC Veterinary Research 2012 8:137
  34. Longevity is the amount of time breeding females stay active in a herd by avoiding death or culling because of illness or reproductive failure. This is a trait of economic relevance in commercial small ruminan...

    Authors: Ashley N Pellerin and Richard Browning Jr
    Citation: BMC Veterinary Research 2012 8:136
  35. Previous research programmes have described muscle biochemical traits and gene expression levels associated with beef tenderness. One of our results concerning the DNAJA1 gene (an Hsp40) was patented. This study ...

    Authors: Jean-Francois Hocquette, Carine Bernard-Capel, Veronique Vidal, Beline Jesson, Hubert Levéziel, Gilles Renand and Isabelle Cassar-Malek
    Citation: BMC Veterinary Research 2012 8:135
  36. Sub-clinical mastitis limits milk production and represents an important barrier to profitable livestock economics worldwide. Milk production from cows in Nigeria is not at optimum levels in view of many facto...

    Authors: Aminu Shittu, Jamilu Abdullahi, Aliyu Jibril, Aminu A Mohammed and Folorunso O Fasina
    Citation: BMC Veterinary Research 2012 8:134
  37. Bovine rotavirus (BRV) infection is common in young calves. This viral infection causes acute diarrhea leading to death. Rapid identification of infected calves is essential to control BRV successfully. Theref...

    Authors: Zhixun Xie, Qing Fan, Jiabo Liu, Yaoshan Pang, Xianwen Deng, Zhiqin Xie, Xie Liji and Mazhar I Khan
    Citation: BMC Veterinary Research 2012 8:133
  38. DNA vaccines offer several advantages over conventional vaccines in the development of effective vaccines against avian influenza virus (AIV). However, one of the limitations of the DNA vaccine in poultry is t...

    Authors: Kian-Lam Lim, Seyed Davoud Jazayeri, Swee Keong Yeap, Noorjahan Banu Mohamed Alitheen, Mohd Hair Bejo, Aini Ideris and Abdul Rahman Omar
    Citation: BMC Veterinary Research 2012 8:132
  39. In the Nordic countries Denmark, Finland, Norway and Sweden, the majority of dairy herds are covered by disease recording systems, in general based on veterinary registration of diagnoses and treatments. Disea...

    Authors: Cecilia Wolff, Mari Espetvedt, Ann-Kristina Lind, Simo Rintakoski, Agneta Egenvall, Ann Lindberg and Ulf Emanuelson
    Citation: BMC Veterinary Research 2012 8:131
  40. Echocardiography and intra-cardiac dimensions have not previously been reported in adult camels despite its potential application for medical purpose. The aim of this study was to describe the results of a pro...

    Authors: Mohamed Tharwat, Fahd Al-Sobayil, Ahmed Ali and Sébastien Buczinski
    Citation: BMC Veterinary Research 2012 8:130
  41. Corticosteroids are illegally used in several countries as growth promoters in veal calves and beef cattle, either alone or in association with sex steroids and β-agonists, especially at low dosages and primar...

    Authors: Marta Vascellari, Katia Capello, Annalisa Stefani, Giancarlo Biancotto, Letizia Moro, Roberto Stella, Giandomenico Pozza and Franco Mutinelli
    Citation: BMC Veterinary Research 2012 8:129
  42. Canine hemangiosarcoma (HSA) is a malignant tumor with poor long-term prognosis due to development of metastasis despite aggressive treatment. The phosphatidyl-inositol-3 kinase/Akt/mammalian target of rapamyc...

    Authors: Atsuko Murai, Samah Abou Asa, Atsushi Kodama, Akihiro Hirata, Tokuma Yanai and Hiroki Sakai
    Citation: BMC Veterinary Research 2012 8:128
  43. Enzyme treatment is the mainstay for management of exocrine pancreatic insufficiency (EPI) in dogs. ‘Enteric-coated’ preparations have been developed to protect the enzyme from degradation in the stomach, but ...

    Authors: Aran Mas, Peter-John M Noble, Peter J Cripps, Daniel J Batchelor, Peter Graham and Alexander J German
    Citation: BMC Veterinary Research 2012 8:127
  44. Disk-associated cervical spondylomyelopathy (DA-CSM) is a multifactorial neurological disorder in which progressive caudal cervical spinal cord compression is mainly caused by one or more intervertebral disk p...

    Authors: Steven De Decker, Ingrid MVL Gielen, Luc Duchateau, Holger A Volk and Luc ML Van Ham
    Citation: BMC Veterinary Research 2012 8:126
  45. Feline leukaemia virus (FeLV) is a pathogen causing fatal illness in cats worldwide, and as such there is a high demand for products to protect against disease. The duration of immunity provided by an inactiva...

    Authors: Stephen Wilson, Juliet Greenslade, Gillian Saunders, Catherine Holcroft, Lynn Bruce, Andy Scobey, Tedd Childers, Gordon Sture and James Thompson
    Citation: BMC Veterinary Research 2012 8:125
  46. L-2-hydroxyglutaric aciduria is a metabolic repair deficiency characterized by elevated levels of L-2-hydroxyglutaric acid in urine, blood and cerebrospinal fluid. Neurological signs associated with the diseas...

    Authors: Fabiana HG Farias, Rong Zeng, Gary S Johnson, G D Shelton, Dominique Paquette and Dennis P O’Brien
    Citation: BMC Veterinary Research 2012 8:124
  47. Infectious diseases in plants, animals and humans are often transmitted indirectly between hosts (or between groups of hosts), i.e. via some route through the environment instead of via direct contacts between...

    Authors: Bram AD van Bunnik, Thomas J Hagenaars, Nico M Bolder, Gonnie Nodelijk and Mart CM de Jong
    Citation: BMC Veterinary Research 2012 8:123
  48. The progression of scrapie is known to be influenced by the amino acid polymorphisms of the host prion protein (PrP) gene. There is no breeding programme for TSE resistance in sheep in Finland, but a scrapie c...

    Authors: Maria Hautaniemi, Hannele Tapiovaara, Sirkka-Liisa Korpenfelt and Liisa Sihvonen
    Citation: BMC Veterinary Research 2012 8:122
  49. The clinical use of autologous platelet concentrates (also known as platelet-rich plasma) on the field of regenerative therapy, in the last decade has been the subject of several studies especially in equine m...

    Authors: Raul F Silva, Jorge U Carmona and Cleuza MF Rezende
    Citation: BMC Veterinary Research 2012 8:121

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