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Erratum to: Urine neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute canine kidney injury
BMC Veterinary Research volume 9, Article number: 228 (2013)
- The original article was published in BMC Veterinary Research 2012 8:248
After the publication of this work , we became aware of the fact that the values of NGAL reported in this study were concentrations of diluted clinic samples; and therefore for the actual concentration of urine NGAL, the value should multiply the dilution factor.
With exception of Figure three (Figure 1 here), all the values of urine NGAL described in this study were detected by in-house ELISA and subsequently were converted to the concentrations corresponding to the values detected with a commercial NGAL ELISA kit by the equation of Y = 0.8855X + 6.5587.
As a consequence, for the concentration of NGAL in urine samples listed in Table two (Table 1 here), all the values have to multiply the dilution factor: 100. And the NGAL concentrations described in abstract (subtitle of Results) should be corrected as follows: At 12 h after surgery, compared to the group without AKI (12 dogs), the NGAL level in the urine of seven dogs with AKI was significantly increased (median 17.840 ng/mL vs. 8.8 ng/mL), and this difference was sustained to 72 h.
As for Figure three (Figure 1 here), the values directly obtained by the commercial NGAL ELISA and by in-house NGAL ELISA need to multiply the dilution factors 100 or 20, respectively. We already corrected the value in the new Figure three (Figure 1 here).
We regret any inconvenience that this inaccuracy in the data used for the original analysis might have caused. We wish to thank Dr. Evence Daure for bringing this matter to our attention.
Lee YJ, Hu YY, Lin YS, Chang CT, Lin FY, Wong ML, Kuo-Hsuan H, Hsu WL: Urine neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute canine kidney injury. BMC Vet Res. 2012, 8: 248-10.1186/1746-6148-8-248.
The online version of the original article can be found at 10.1186/1746-6148-8-248
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Lee, Y., Hu, Y., Lin, Y. et al. Erratum to: Urine neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute canine kidney injury. BMC Vet Res 9, 228 (2013). https://doi.org/10.1186/1746-6148-9-228