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  1. After a decade of silence, an outbreak of the contagious and Asian endemic disease, goat pox re-emerged in North Vietnam affecting more than 1800 heads with a mortality rate of 6.5%. The inevitable impact of g...

    Authors: Trang Hong Pham, Nor Yasmin Abdul Rahaman, Mohd Azmi Mohd Lila, Huong Lan Thi Lai, Lan Thi Nguyen, Giap Van Nguyen, Bo Xuan Ha, Hieu Nguyen, Hanh Duc Vu and Mustapha M. Noordin

    Citation: BMC Veterinary Research 2021 17:115

    Content type: Research article

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  2. Pyroptosis plays a pivotal role in the pathogenesis of many inflammatory diseases. The molecular mechanism by which pyroptosis is induced in macrophages following infection with pathogenic E. coli high pathogenic...

    Authors: Chunlan Shan, Shushu Miao, Chaoying Liu, Bo Zhang, Weiwei Zhao, Hao Wang, Wei Yang, Jinlong Cha, Ru Zhao, Peng Xiao and Hong Gao

    Citation: BMC Veterinary Research 2021 17:114

    Content type: Research article

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  3. Pet dogs are important companion animals that share the environment within households, and play an important role in local community life. In addition, pet dogs also are reservoirs of zoonotic agents, including R...

    Authors: Jian-Wei Shao, Xin-Yan Yao, Xu-Dong Song, Wen-Jun Li, Hui-Lan Huang, Shu-Jian Huang and Xue-Lian Zhang

    Citation: BMC Veterinary Research 2021 17:113

    Content type: Research article

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  4. Dogs are domesticated wolves. Change of living environment, such as diet and veterinary care may affect the gut bacterial flora of dogs. The aim of this study was to assess the gut bacterial diversity and func...

    Authors: Yuting Liu, Bo Liu, Chengwu Liu, Yumiao Hu, Chang Liu, Xiaoping Li, Xibao Li, Xiaoshuang Zhang, David M. Irwin, Zhiqiang Wu, Zeliang Chen, Qi Jin and Shuyi Zhang

    Citation: BMC Veterinary Research 2021 17:112

    Content type: Research article

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  5. Erysipelas, caused by Erysipelothrix rhusiopathiae (ER), is an important emerging disease in free-range and organic egg-production. The aim of the present study was to assess if quantification of ER specific IgY ...

    Authors: Eva Wattrang, Helena Eriksson, Ann Albihn and Tina Sørensen Dalgaard

    Citation: BMC Veterinary Research 2021 17:111

    Content type: Research article

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  6. Objective outcome measures capable of tracking different aspects of functional recovery in dogs with acute intervertebral disc herniation are needed to optimize physical rehabilitation protocols. Normal, pre-i...

    Authors: Jessica E. Linder, Stephanie Thomovsky, Jessica Bowditch, Mallory Lind, Kristine A. Kazmierczak, Gert J. Breur and Melissa J. Lewis

    Citation: BMC Veterinary Research 2021 17:110

    Content type: Research article

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  7. Effective animal health surveillance systems require reliable, high-quality, and timely data for decision making. In Tanzania, the animal health surveillance system has been relying on a few data sources, whic...

    Authors: Janeth George, Barbara Häsler, Erick Komba, Calvin Sindato, Mark Rweyemamu and James Mlangwa

    Citation: BMC Veterinary Research 2021 17:109

    Content type: Research article

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  8. Candida is the common conditionally pathogenic fungus that infected human and animal clinically. C. tropicalis had been isolated from the skin and hair of healthy pigs, but with no report of fatal infection in ga...

    Authors: Lufeng Zhai, Ying Zhou, Yingxia Wu, Yunyun Jin, Qiaoyan Zhu, Shengguo Gao, Xuefeng Li, Zhe Sun, Yan Xiao, Baicheng Huang and Kegong Tian

    Citation: BMC Veterinary Research 2021 17:108

    Content type: Case Report

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  9. Klebsiella pneumonia, a Gram-negative bacterium belonging to the genus Enterobacter, causes many human and livestock diseases. Notably, infected goats may develop pneumonia, septicemia, which can lead to occasion...

    Authors: Ruichang Chen, Hongqi Shang, Xiangyun Niu, Jin Huang, Yongqiang Miao, Zhou Sha, Liting Qin, He Huang, Duo Peng and Ruiliang Zhu

    Citation: BMC Veterinary Research 2021 17:107

    Content type: Research article

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  10. Strongylid nematode infections may negatively affect both animal health and welfare, with deleterious consequences for livestock productivity. Many farmers in recent decades have relied on anthelmintics as the...

    Authors: Jaroslav Vadlejch, Iveta Angela Kyriánová, Marián Várady and Johannes Charlier

    Citation: BMC Veterinary Research 2021 17:106

    Content type: Research article

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  11. Alpha-2u globulin nephropathy mainly shows toxicological pathology only in male rats induced by certain chemicals and drugs, such as levamisole (antiparasitic and anticancer drugs). Streptozotocin (STZ) is als...

    Authors: Kanchana Kengkoom, Wannee Angkhasirisap, Tapanee Kanjanapruthipong, Rongdej Tungtrakanpoung, Khwanchanok Tuentam, Naphatson Phansom and Sumate Ampawong

    Citation: BMC Veterinary Research 2021 17:105

    Content type: Research article

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  12. Domestic cats rarely develop hepatocellular carcinoma. The reason for the low prevalence is unknown. Reductions in hepatocellular ploidy have been associated with hepatic carcinogenesis. Recent work in mice ha...

    Authors: Jacqueline Post, Ingeborg M. Langohr, Cynthia R.L. Webster, Peter Mottram, Chin-Chi Liu and Andrea Johnston

    Citation: BMC Veterinary Research 2021 17:104

    Content type: Research article

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  13. Status epilepticus (SE) or prolonged epileptic seizure activity is a common neurological emergency with a high mortality rate and, if left untreated, can lead to irreversible cerebral damage and systemic compl...

    Authors: Marios Charalambous, Holger A. Volk, Luc Van Ham and Sofie F. M. Bhatti

    Citation: BMC Veterinary Research 2021 17:103

    Content type: Review

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  14. In free-ranging reptile populations, bacterial, fungal, viral and parasitic pathogens may affect hosts through impairment in movements, thermoregulation, reproduction, survival, and population dynamics. The sp...

    Authors: Livio Galosi, Anna Rita Attili, Stefania Perrucci, Francesco C. Origgi, Adolfo Maria Tambella, Giacomo Rossi, Vincenzo Cuteri, Maira Napoleoni, Nicholas Aconiti Mandolini, Gianni Perugini and Victor J. T. Loehr

    Citation: BMC Veterinary Research 2021 17:102

    Content type: Research article

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  15. Magnetic resonance imaging (MRI) is the most versatile and informative imaging modality for the diagnosis of locomotor injuries in many animal species; however, veterinary literature describing the MRI of the ...

    Authors: Zakriya Ali Al Mohamad, Usama Hagag, Mohamed Gomaa Tawfiek and Ayman El Nahas

    Citation: BMC Veterinary Research 2021 17:101

    Content type: Research article

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  16. Chronic intermittent or persistent diarrhoea is a common condition in dogs and may be a reflex of gastrointestinal or non-gastrointestinal disorders. Besides diarrhoea, many athletes experience other gastroint...

    Authors: J. C. Alves, A. Santos, P. Jorge and A. Pitães

    Citation: BMC Veterinary Research 2021 17:100

    Content type: Research article

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  17. The horses’ backs are particularly exposed to overload and injuries due to direct contact with the saddle and the influence of e.g. the rider’s body weight. The maximal load for a horse’s back during riding ha...

    Authors: Malgorzata Masko, Marta Borowska, Malgorzata Domino, Tomasz Jasinski, Lukasz Zdrojkowski and Zdzislaw Gajewski

    Citation: BMC Veterinary Research 2021 17:99

    Content type: Research article

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  18. Ménétrier-like disease is a rare hypertrophic canine gastropathy, reported in only seven dogs. Clinical signs are vomiting, anorexia and weight loss. Macroscopically, giant cerebriform gastric mucosal folds ar...

    Authors: E. Lagerstedt, T. Spillmann, N. Airas, L. Solano-Gallego and S. Kilpinen

    Citation: BMC Veterinary Research 2021 17:98

    Content type: Case Report

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  19. Lipopolysaccharides (LPS) derived from gram-negative bacterial are often regarded as primary inducer of bovine mammary inflammation. This study evaluated the biological response of metformin activated AMPK sig...

    Authors: Tianle Xu, Xinyue Wu, Xubin Lu, Yusheng Liang, Yongjiang Mao, Juan J. Loor and Zhangping Yang

    Citation: BMC Veterinary Research 2021 17:97

    Content type: Research article

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  20. Mesenchymal stem cells (MSCs) have generated a great amount of interest in recent years as a novel therapeutic application for improving the quality of pet life and helping them free from painful conditions an...

    Authors: Huina Luo, Dongsheng Li, Zhisheng Chen, Bingyun Wang and Shengfeng Chen

    Citation: BMC Veterinary Research 2021 17:96

    Content type: Research article

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  21. Brucellosis is a contagious zoonotic disease of great public health and economic significance especially in developing countries. The disease affects humans and several species of livestock and wildlife. Studi...

    Authors: Robert Aruho, Ewan T. MacLeod, Leonard Manirakiza and Innocent B. Rwego

    Citation: BMC Veterinary Research 2021 17:95

    Content type: Research article

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  22. Trichinellosis, caused by Trichinella spiralis, is a serious foodborne parasitic zoonosis. Tibetan pig is an infrequent, endemic plateau pig species, mainly distributed in Tibet Plateau, China. Because of the fre...

    Authors: Li Tingting, Li Wenhui, Zhang Nianzhang, Qu Zigang, John A Ohiolei, Li Li, Yan Hongbin, Jia Wanzhong and Fu Baoquan

    Citation: BMC Veterinary Research 2021 17:94

    Content type: Research article

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  23. Animal vaccination is an important way to stop the spread of diseases causing immense damage to livestock and economic losses and the potential transmission to humans. Therefore effective method for vaccine pr...

    Authors: Halima Rhazi, Najete Safini, Karima Mikou, Meryeme Alhyane, Khalid Omari Tadlaoui, Xiangliang Lin, Nandini P. Venkatesan and Mehdi Elharrak

    Citation: BMC Veterinary Research 2021 17:93

    Content type: Research article

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  24. Between February and April 2016, a slight increase in mortality was observed in a colony consisting of 400 captive Seba’s short-tailed bats (Carollia perspicillata). These animals cohabited with other nocturnal a...

    Authors: K. Hahn, I. B. Veiga, M. Schediwy, D. Wiederkehr, M. Meniri, M. Schneeberger, P. Rüegg-van den Broek, C. Gurtner, N. J. Fasel, S. Kittl, M. Fredriksson-Ahomaa, S. Schmitt and N. Stokar-Regenscheit

    Citation: BMC Veterinary Research 2021 17:92

    Content type: Research article

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  25. Ticks transmit several diseases that result in high morbidity and mortality in livestock. Tick-borne diseases are an economic burden that negatively affect livestock production, cost countries billions of doll...

    Authors: Munyaradzi Davis Shekede, Silvester Maravanyika Chikerema, Moregood Spargo, Isaiah Gwitira, Samuel Kusangaya, Aldridge Nyasha Mazhindu and Daud Nyosi Ndhlovu

    Citation: BMC Veterinary Research 2021 17:91

    Content type: Research article

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  26. While a necessary step toward enhancing rigor and reproducibility of veterinary clinical trials conducted on the translational spectrum includes understanding the current state of the field, no broad assessmen...

    Authors: Sarah A. Moore, Angela McCleary-Wheeler, Joan R Coates, Natasha Olby and Cheryl London

    Citation: BMC Veterinary Research 2021 17:90

    Content type: Guidelines

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  27. Prior studies have suggested that pimobendan is associated with several positive effects in cats, including improved survival in cats with congestive heart failure and improved left atrial function in research...

    Authors: Maureen S. Oldach, Yu Ueda, Eric S. Ontiveros, Samantha L. Fousse, Lance C. Visser and Joshua A. Stern

    Citation: BMC Veterinary Research 2021 17:89

    Content type: Research article

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  28. Porcine reproductive and respiratory syndrome (PRRS) is a threat to pig production worldwide. Our objective was to understand mechanisms of persistence of PRRS virus (PRRSV) in tonsil. Transcriptome data from ...

    Authors: Qian Dong, Joan K. Lunney, Kyu-Sang Lim, Yet Nguyen, Andrew S. Hess, Hamid Beiki, Raymond R. R. Rowland, Kristen Walker, James M. Reecy, Christopher K. Tuggle and Jack C. M. Dekkers

    Citation: BMC Veterinary Research 2021 17:88

    Content type: Research article

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  29. Bovine Viral Diarrhea virus (BVDV) is one of important diseases of cattle worldwide causing economic losses to the cattle industry primarily due to increased premature culling and decreased reproductive perfor...

    Authors: Erdachew Yitagesu, Wendi Jackson, Nigatu Kebede, Woutrina Smith and Tsegaw Fentie

    Citation: BMC Veterinary Research 2021 17:87

    Content type: Research article

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  30. The discovery of the superbug mcr-1-positive Escherichia coli (MCRPEC) has drew greet attention. Swine-origin multi-drug resistant MCRPEC has been a potential threat to public health and safety. However, there we...

    Authors: Jingzhi Yuan, Xiaoye Wang, Dali Shi, Qiang Ge, Xingxing Song, Wen Hu, Deyuan Wei, Chenling Ge, Xun Li and Chuanhuo Hu

    Citation: BMC Veterinary Research 2021 17:86

    Content type: Research article

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  31. Lymphocytic neoplasms with frequent reactive lymphocytes are uncommonly reported in dogs, and can pose a diagnostic challenge. Different diagnostic modalities such as cytology, flow cytometry, histopathology, ...

    Authors: Gary Kwok Cheong Lee, Dorothee Bienzle, Stefan Matthias Keller, Mei-Hua Hwang, Nikos Darzentas, Haiyang Chang, Emily Rätsep, Rebecca Egan and Janet Beeler-Marfisi

    Citation: BMC Veterinary Research 2021 17:85

    Content type: Case Report

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  32. Osteosarcoma is a malignant mesenchymal bone tumor. Although it is a common tumor in the appendicular skeleton of dogs and cats, it is rarely reported in birds. Retroviruses are usually associated with solid t...

    Authors: Jefferson Bruno Soares Oliveira, Ayisa Rodrigues de Oliveira, Daniel Oliveira dos Santos, Thaynara Parente de Carvalho, Larissa Giannini Alves Moreira, Herlandes Penha Tinoco, Carlyle Mendes Coelho, Hannah Luiza Gonsalves Coelho, Maria Clara de Paiva Zucherato, Sandra Yuliet Marín-Gómez, Camila Siqueira Costa, Nelson R. S. Martins and Renato Lima Santos

    Citation: BMC Veterinary Research 2021 17:84

    Content type: Case Report

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  33. Harmonized institutional processes and reviewer training are vital to maintain integrity and ethical rigor of the veterinary clinical research pipeline and are a prerequisite to future work that might establis...

    Authors: S. A. Moore, A. O’Kell, H. Borghese, R. Garabed, H. O’Meara and P. Baneux

    Citation: BMC Veterinary Research 2021 17:83

    Content type: Guidelines

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  34. Respiratory diseases are among the most important factors affecting swine farm productivity in Canada. The objectives of this study were to investigate antibody responses to porcine reproductive and respirator...

    Authors: Elana Raaphorst, Abdolvahab Farzan, Robert M. Friendship and Brandon N. Lillie

    Citation: BMC Veterinary Research 2021 17:82

    Content type: Research article

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  35. Although dogs are a commonly owned companion animal in the UK, the species experiences many health problems that are predictable from demographic information. This study aimed to use anonymised veterinary clin...

    Authors: Dan G. O’Neill, Hannah James, Dave C. Brodbelt, David B. Church and Camilla Pegram

    Citation: BMC Veterinary Research 2021 17:69

    Content type: Research article

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  36. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Rebecca Ricci, Daniele Conficoni, Giada Morelli, Carmen Losasso, Leonardo Alberghini, Valerio Giaccone, Antonia Ricci and Igino Andrighetto

    Citation: BMC Veterinary Research 2021 17:81

    Content type: Correction

    Published on:

    The original article was published in BMC Veterinary Research 2018 14:209

  37. Genotype S H9N2 viruses have become predominant in poultry in China since 2010. These viruses frequently donate their whole internal gene segments to other emerging influenza A subtypes such as the novel H7N9,...

    Authors: Xiuli Li, Min Gu, Xiaoquan Wang, Ruyi Gao, Xinxin Bu, Xiaoli Hao, Jing Ma, Jiao Hu, Shunlin Hu, Xiaowen Liu, Sujuan Chen, Daxin Peng, Xinan Jiao and Xiufan Liu

    Citation: BMC Veterinary Research 2021 17:80

    Content type: Research article

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  38. Livestock play an important role as reservoir of enteric pathogens and antimicrobial resistance (AMR), a health and economic concern worldwide. However, little is known regarding the transmission and maintenan...

    Authors: Johan Espunyes, Oscar Cabezón, Andrea Dias-Alves, Pol Miralles, Teresa Ayats and Marta Cerdà-Cuéllar

    Citation: BMC Veterinary Research 2021 17:79

    Content type: Research article

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  39. Proxies are mathematical calculations based on fasting glucose and/or insulin concentrations developed to allow prediction of insulin sensitivity (IS) and β-cell response. These proxies have not been evaluated...

    Authors: Sanna Lindåse, Katarina Nostell, Peter Bergsten, Anders Forslund and Johan Bröjer

    Citation: BMC Veterinary Research 2021 17:78

    Content type: Research article

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  40. In humans, the drug metabolizing enzyme CYP2D6 is highly polymorphic resulting in substantial differences in the metabolism of drugs including anti-arrhythmics, neuroleptics, and opioids. The objective of this...

    Authors: S. R. Gretler, C. J. Finno, P. H. Kass and H. K. Knych

    Citation: BMC Veterinary Research 2021 17:77

    Content type: Research article

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  41. French bulldogs exhibit significantly larger femoral external rotation and abduction than other breeds. We were curious as to whether this peculiar leg kinematic affects patellar motion and/or might induce med...

    Authors: Silvia V. Lehmann, Emanuel Andrada, Roxana Taszus, Daniel Koch and Martin S. Fischer

    Citation: BMC Veterinary Research 2021 17:76

    Content type: Research article

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  42. Respiratory diseases are the second most common cause of illnesses in horses, their etiology can be viral, bacterial, immune-mediated, or mechanical (Racklyeft and Love DN, Aust Vet J 78:549–59, 2000; Austin e...

    Authors: Elisabetta Mondo, Riccardo Rinnovati, Alessandro Spadari, Federica Giacometti, Andrea Serraino, Federica Savini and Silvia Piva

    Citation: BMC Veterinary Research 2021 17:75

    Content type: Case Report

    Published on:

  43. Marigold (Tagetes erecta L) accounts for over half of the world’s loose flower production, and marigold crop residue (MCR) are abundantly available and should be used as a forage. In this study, MCR from the last...

    Authors: Zhijiang Hou, Jianyong Liu, Ming Cai, Yanpei Liu, Lan Mu, Yuee Gao, Metha Wanapat and Bizhi Huang

    Citation: BMC Veterinary Research 2021 17:74

    Content type: Research article

    Published on:

  44. Ureteral atresia is the congenital absence of a ureteral opening, resulting in a blind-ended ureter that fails to terminate at the urinary bladder. Consequently, severe hydroureter and hydronephrosis occur ips...

    Authors: Megan Zalek, Rohan Shah and Timothy Bolton

    Citation: BMC Veterinary Research 2021 17:73

    Content type: Case Report

    Published on:

  45. Streptococcus suis is an important pathogen that causes severe diseases mostly in weaned piglets. Only available vaccines in the field are those composed of killed bacteria (bacterins) but data about their effect...

    Authors: Lorelei Corsaut, Léa Martelet, Guillaume Goyette-Desjardins, Guy Beauchamp, Martine Denicourt, Marcelo Gottschalk and Mariela Segura

    Citation: BMC Veterinary Research 2021 17:72

    Content type: Research article

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  46. In dogs with atopic dermatitis, intradermal testing (IDT) or allergen specific IgE serological testing are routinely employed to identify causative allergens. These allergens can then be used for allergen-spec...

    Authors: N. Khantavee, C. Chanthick, A. Tungtrongchitr, N. Techakriengkrai, S. Suradhat, N. Sookrung, S. Roytrakul and N. Prapasarakul

    Citation: BMC Veterinary Research 2021 17:71

    Content type: Research article

    Published on:

  47. Among the 6–8 million animals that enter the rescue shelters every year, nearly 3–4 million (i.e., 50% of the incoming animals) are euthanized, and 10–25% of them are put to death specifically because of shelt...

    Authors: Janae Bradley and Suchithra Rajendran

    Citation: BMC Veterinary Research 2021 17:70

    Content type: Research article

    Published on:

  48. The effects of safflower oil and vitamin C (Vit. C) inclusion in broiler chicken diets on the growth performance, apparent ileal digestibility coefficient “AID%” of amino acids, intestinal histology, behavior,...

    Authors: Shimaa A. Amer, Wafaa A. M. Mohamed, Heba S. A. Gharib, Naif A. Al-Gabri, Ahmed Gouda, Mohamed Tharwat Elabbasy, Ghada I. Abd El-Rahman and Anaam E. Omar

    Citation: BMC Veterinary Research 2021 17:68

    Content type: Research article

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  49. Umbilical vein bacterial infections may cause liver abscesses during bacterial ascent. A single liver abscess can be surgically treated by marsupialization, but a risk of recurrence or non-healing remains. Mor...

    Authors: Reiichiro Sato, Kazutaka Yamada, Taiki Yokoyama, Koki Tanimoto, Shoko Takeuchi, Natsumi Tatsuzawa, Shiho Nakui, Hiroyuki Satoh, Mahmoud Fadul and Adrian Steiner

    Citation: BMC Veterinary Research 2021 17:67

    Content type: Case Report

    Published on:

  50. Enterocytozoon hepatopenaei (EHP) is an enteric pathogen that affects Penaeus vannamei and Penaeus monodon shrimp in many SE Asian countries. In the western hemisphere, EHP was reported for the first time in 2016...

    Authors: L. F. Aranguren Caro, F. Alghamdi, K. De Belder, J. Lin, H. N. Mai, J. Millabas, Y. Alrehaili, A. Alazwari, S. Algetham and A. K. Dhar

    Citation: BMC Veterinary Research 2021 17:65

    Content type: Research article

    Published on:

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