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  1. The antimetabolite 6-thioguanine (6-TG) has been used to treat both human and canine lymphoid malignancies. 6-TG has been shown to be epigenetically active as a demethylating agent in a human lymphoma cell lin...

    Authors: Brian K Flesner, Senthil R Kumar and Jeffrey N Bryan
    Citation: BMC Veterinary Research 2014 10:290
  2. Porcine circovirus 2 is the primary agent responsible for inducing a group of associated diseases known as Porcine Circovirus Associated Diseases (PCVAD), which can have detrimental effects on production effic...

    Authors: Taylor B Engle, Erin E Jobman, Timothy W Moural, Autumn M McKnite, Justin W Bundy, Sarah Y Barnes, Emily H Davis, Judith A Galeota, Thomas E Burkey, Graham S Plastow, Stephen D Kachman and Daniel C Ciobanu
    Citation: BMC Veterinary Research 2014 10:286
  3. Influenza A(H1N1)pdm09 virus infection in Norwegian pigs was largely subclinical. This study tested the hypothesis that the infection causes negligible impact on pigs’ growth performance in terms of feed conve...

    Authors: Chiek Er, Bjørn Lium, Saraya Tavornpanich, Peer Ola Hofmo, Hilde Forberg, Anna Germundsson Hauge, Carl Andreas Grøntvedt, Tore Framstad and Edgar Brun
    Citation: BMC Veterinary Research 2014 10:284
  4. The microscopic agglutination test (MAT), the standard method for serological diagnosis of leptospirosis, may present limitations regarding its sensitivity. Current studies suggest that Leptospira immunoglobulin-...

    Authors: Sabrina Thomé, Carolina Lessa-Aquino, Albert Icksang Ko, Walter Lilenbaum and Marco Alberto Medeiros
    Citation: BMC Veterinary Research 2014 10:288
  5. The (mis)use of fluoroquinolones in the fowl industry has led to an alarming incidence of fluoroquinolone resistance in pathogenic as well as commensal bacteria. Next to simply reducing antimicrobial consumpti...

    Authors: Mathias Devreese, Gunther Antonissen, Siegrid De Baere, Patrick De Backer and Siska Croubels
    Citation: BMC Veterinary Research 2014 10:289
  6. Recently identified porcine circovirus-like virus P1 has the smallest DNA viral genome. In this study, we identified the viral genes and their corresponding mRNA transcripts.

    Authors: Li-bin Wen, Feng-zhi Wang, Kong-wang He, Bin Li, Xiao-min Wang, Rong-li Guo and Jian-ping Xie
    Citation: BMC Veterinary Research 2014 10:287
  7. Classical swine fever virus (CSFV) infection causes significant losses of pigs, which is characterized by hemorrhage, disseminated intravascular coagulation and leucopenia. The swine vascular endothelial cell ...

    Authors: Lei He, Yanming Zhang, Yanqin Fang, Wulong Liang, Jihui Lin and Min Cheng
    Citation: BMC Veterinary Research 2014 10:279
  8. Melioidosis caused by Burkholderia (B.) pseudomallei is an endemic zoonotic disease mainly reported from northern Australia and Southeast Asia. In Europe, cases of human melioidosis have been reported only from p...

    Authors: Mandy C Elschner, Jan Hnizdo, Ivonne Stamm, Hosny El-Adawy, Katja Mertens and Falk Melzer
    Citation: BMC Veterinary Research 2014 10:283
  9. Sepsis is a serious and potentially life-threatening condition and early diagnosis and appropriate treatment is crucial for survival. Pyometra is one of the most common diseases in intact female dogs. The dise...

    Authors: Supranee Jitpean, Ann Pettersson, Odd V Höglund, Bodil Ström Holst, Ulf Olsson and Ragnvi Hagman
    Citation: BMC Veterinary Research 2014 10:273
  10. Poultry remains a major source of foodborne bacterial infections. A variety of additives with presumed anti-microbial and/or growth-promoting effects are commonly added to poultry feed during commercial grow-o...

    Authors: Brian B Oakley, R Jeff Buhr, Casey W Ritz, Brian H Kiepper, Mark E Berrang, Bruce S Seal and Nelson A Cox
    Citation: BMC Veterinary Research 2014 10:282
  11. Bovine venereal campylobacteriosis is caused by Campylobacter fetus subsp. venerealis and its glycerine-tolerant variant Campylobacter fetus subsp. venerealis biovars intermedius. The disease can be economically ...

    Authors: Isabelle Truyers, Tim Luke, David Wilson and Neil Sargison
    Citation: BMC Veterinary Research 2014 10:280
  12. The aim of this study was to determine the ability of two feed additives, a fumarate-malate (FM) and a polyphenol-essential oil mixture (PM), in attenuating the drop of ruminal pH and the metabolic and immune ...

    Authors: Roberta De Nardi, Giorgio Marchesini, Jan C Plaizier, Shucong Li, Ehsan Khafipour, Rebecca Ricci, Igino Andrighetto and Severino Segato
    Citation: BMC Veterinary Research 2014 10:277
  13. Stoned olive pomace (SOP), which represents approximately 50% of the conversion process of olive in oil, is largely not-utilized and creates costs for its disposal and problems related to environmental impact. In...

    Authors: Grazia Pallara, Arianna Buccioni, Roberta Pastorelli, Sara Minieri, Marcello Mele, Stefano Rapaccini, Anna Messini, Mariano Pauselli, Maurizio Servili, Luciana Giovannetti and Carlo Viti
    Citation: BMC Veterinary Research 2014 10:271
  14. Cadherins are calcium-dependent cell-to-cell adhesion glycoproteins playing a critical role in the formation and maintenance of normal tissue architecture. In normal mammary gland, E-cadherin is expressed by l...

    Authors: Ana Catarina Figueira, Catarina Gomes, Joana Tavares de Oliveira, Hugo Vilhena, Júlio Carvalheira, Augusto JF de Matos, Patrícia Dias Pereira and Fátima Gärtner
    Citation: BMC Veterinary Research 2014 10:270
  15. Pasteurella multocida causes numerous economically relevant diseases in livestock including rabbits. Immunisation is only variably effective. Prophylactic antibiotics are used in some species but are contra-indic...

    Authors: Orsolya Palócz, János Gál, Paul Clayton, Zoltán Dinya, Zoltán Somogyi, Csaba Juhász and György Csikó
    Citation: BMC Veterinary Research 2014 10:276
  16. Campylobacter jejuni is commonly found in the gastrointestinal tract of many food-animals including sheep without causing visible clinical symptoms of disease. However, C. jejuni has been implicated in ovine abor...

    Authors: Yasser M Sanad, Kwonil Jung, Isaac Kashoma, Xiaoli Zhang, Issmat I Kassem, Yehia M Saif and Gireesh Rajashekara
    Citation: BMC Veterinary Research 2014 10:274
  17. Infection pathways of S. aureus udder infections in heifers are still not well understood. One hypothesis is that calves become infected with S. aureus via feeding mastitis milk. Especially on small-scale farms, ...

    Authors: Katharina Abb-Schwedler, Ariane Maeschli, Renate Boss, Hans U Graber, Adrian Steiner and Peter Klocke
    Citation: BMC Veterinary Research 2014 10:267
  18. In the first phase of life, in which the immune system is primed and the bacterial colonization of epithelial surfaces takes place, foals are highly susceptible to bacterial infections. Next to strategies to o...

    Authors: Johannes Cornelis Vendrig, Luc Edgar Coffeng and Johanna Fink-Gremmels
    Citation: BMC Veterinary Research 2014 10:278
  19. Axial osteitis of the proximal sesamoid bones and desmitis of the intersesamoidean ligament has been described in Friesian horses as well as in other breeds. The objectives of this study were to review the out...

    Authors: Harold Brommer, Margreet Voermans, Stefanie Veraa, Antoon JM van den Belt, Annette van der Toorn, Margreet Ploeg, Andrea Gröne and Willem Back
    Citation: BMC Veterinary Research 2014 10:272
  20. Sporotrichosis is a mycotic infectious disease that is generally acquired by traumatic inoculation of contaminated materials especially from plant debris or through bites and scratches from diseased animals, s...

    Authors: Hildebrando Montenegro, Anderson Messias Rodrigues, Maria Adelaide Galvão Dias, Elisabete Aparecida da Silva, Fernanda Bernardi and Zoilo Pires de Camargo
    Citation: BMC Veterinary Research 2014 10:269
  21. Cranial cruciate ligament (CCL) rupture is a very common cause of pelvic limb lameness in dogs. Few studies, using objective and validated outcome evaluation methods, have been published to evaluate long-term ...

    Authors: Sari H Mölsä, Heli K Hyytiäinen,, Anna K Hielm-Björkman and Outi M Laitinen-Vapaavuori
    Citation: BMC Veterinary Research 2014 10:266
  22. Acquired equine polyneuropathy (AEP) is an emerging disease in horses in Sweden, Norway and Finland since 1995. Affected horses show bilateral pelvic limb knuckling and weakness, sometimes progressing to recum...

    Authors: Cecilia Wolff, Agneta Egenvall, Siv Hanche-Olsen and Gittan Gröndahl
    Citation: BMC Veterinary Research 2014 10:265
  23. Gastrointestinal nematodes are an important cause of reduced performance in cattle. Previous studies in Europe showed that after anthelmintic treatment an average gain in milk production of around 1 kg per day...

    Authors: Sien H Verschave, Jozef Vercruysse, Andrew Forbes, Geert Opsomer, Miel Hostens, Luc Duchateau and Johannes Charlier
    Citation: BMC Veterinary Research 2014 10:264
  24. Peste des Petits Ruminants (PPR), also known as Goat Plague, occurs in goats, sheep and related species. It is caused by a morbillivirus in the family Paramyxoviridae. In Bangladesh PPR is endemic and it causes s...

    Authors: Emdadul Haque Chowdhury, Ataur Rahman Bhuiyan, Mohammad Mushfiqur Rahman, Mohammad Sahinur Alam Siddique and Mohammad Rafiqul Islam
    Citation: BMC Veterinary Research 2014 10:263
  25. As a consequence of the increasing levels of anthelmintic resistance in cyathostomes, new strategies for equine parasite control are being implemented. To assess the potential risks of these, the occurrence of...

    Authors: Stephanie Schneider, Kurt Pfister, Anne M Becher and Miriam C Scheuerle
    Citation: BMC Veterinary Research 2014 10:262
  26. Bovine respiratory disease (BRD) is a costly feature of modern cattle production. Early and accurate detection of BRD may prove useful in the successful management of this disease. The primary objective of the...

    Authors: Charles A Hinds, Andrew J Niehaus, Christopher Premanandan, Paivi J Rajala-Schultz, Donald M Rings and Jeffrey Lakritz
    Citation: BMC Veterinary Research 2014 10:261
  27. The aim of the present study was to evaluate the feasibility of using a telephone survey in gaining an understanding of the possible herd and management factors influencing the performance (i.e. safety and eff...

    Authors: Heiko Nathues, Johanna Meyer-Hamme, Petra Maass, Ruediger Goessl, Wibke Stansen, Rolf Steens and Elisabeth grosse Beilage
    Citation: BMC Veterinary Research 2014 10:260
  28. The efficacy, acceptability and tolerability of the new oral phosphate binder Lenziaren® (SBR759) were evaluated in a randomized parallel-group design study in 36 healthy cats (n = 6 per group). Five groups we...

    Authors: Jonathan N King, Heidi L Erasmus, Peet C Delport, Ina CJ Bester and Wolfgang Seewald
    Citation: BMC Veterinary Research 2014 10:258
  29. Since 2009, large-scale Streptococcus agalactiae infections have broken out in cultured tilapia farms in China, resulting in considerable economic losses. Screening of the surface proteins is required to identify...

    Authors: Guangjin Liu, Wei Zhang, Yongjie Liu, Huochun Yao, Chengping Lu and Pao Xu
    Citation: BMC Veterinary Research 2014 10:259
  30. Schmallenberg virus (SBV) was first detected in November 2011 in Germany and then rapidly spread throughout Europe. In beef suckler farms, clinical signs are mainly associated with reproductive disorders, part...

    Authors: Didier Raboisson, Agnès Waret-Szkuta, Jonathan Rushton, Barbara Häsler and Pablo Alarcon
    Citation: BMC Veterinary Research 2014 10:254
  31. Mycoplasma bovis is a worldwide pathogen, causative agent of pneumonia, mastitis, arthritis, and a variety of other symptoms in cattle. The economic losses due to mycoplasma pneumonia could be reduced by antibiot...

    Authors: Kinga M Sulyok, Zsuzsa Kreizinger, Lilla Fekete, Veronika Hrivnák, Tibor Magyar, Szilárd Jánosi, Nóra Schweitzer, Ibolya Turcsányi, László Makrai, Károly Erdélyi and Miklós Gyuranecz
    Citation: BMC Veterinary Research 2014 10:256
  32. Various antiepileptic drugs (AEDs) are used for the management of canine idiopathic epilepsy (IE). Information on their clinical efficacy remains limited. A systematic review was designed to evaluate existing ...

    Authors: Marios Charalambous, David Brodbelt and Holger A Volk
    Citation: BMC Veterinary Research 2014 10:257
  33. In order to characterize the functional properties of canine protein C (CnPC), the zymogen needs to be purified from plasma. The goals of this study were (1) to purify protein C from fresh frozen canine plasma...

    Authors: Valerie M Wong, Dorothee Bienzle, M Anthony Hayes, Paul Taylor and R Darren Wood
    Citation: BMC Veterinary Research 2014 10:251
  34. Opioid-induced immobilization is associated with severe respiratory depression in the white rhinoceros. We evaluated the efficacy of butorphanol and oxygen insufflation in alleviating opioid-induced respirator...

    Authors: Anna Haw, Markus Hofmeyr, Andrea Fuller, Peter Buss, Michele Miller, Gregory Fleming and Leith Meyer
    Citation: BMC Veterinary Research 2014 10:253
  35. A variety of analgesic agents are available, and which one can be used in dogs and cats is a highly controversial issue, existing however a fear in the use of opiates due to possible adverse effects that these...

    Authors: Marina C Evangelista, Rodrigo A Silva, Larissa B Cardozo, Marcia A P Kahvegian, Thais C Rossetto, Julia M Matera and Denise T Fantoni
    Citation: BMC Veterinary Research 2014 10:252
  36. Sonographic ophthalmic examinations have become increasingly important in veterinary medicine. If the velocity of ultrasound in ocular tissues is known, the A-mode ultrasound method may be used to determine th...

    Authors: Ulrike Meister, Bernhard Ohnesorge, Daniel Körner and Michael H Boevé
    Citation: BMC Veterinary Research 2014 10:250
  37. The Schmallenberg virus (SBV) emerged in Europe in 2011 and caused a widespread epidemic in ruminants.

    Authors: Morgane Dominguez, Kristel Gache, Anne Touratier, Jean-Baptiste Perrin, Alexandre Fediaevsky, Eric Collin, Emmanuel Bréard, Corinne Sailleau, Cyril Viarouge, Gina Zanella, Stephan Zientara, Pascal Hendrikx and Didier Calavas
    Citation: BMC Veterinary Research 2014 10:248
  38. Right ventricular (RV) volume and function are important diagnostic and prognostic factors in dogs with primary or secondary right-sided heart failure. The complex shape of the right ventricle and its retroste...

    Authors: Anne K Sieslack, Peter Dziallas, Ingo Nolte, Patrick Wefstaedt and Stephan O Hungerbühler
    Citation: BMC Veterinary Research 2014 10:242
  39. Active surveillance of peste des petits ruminants (PPR) should ease prevention and control of this disease widely present across Africa, Middle East, central and southern Asia. PPR is now present in Turkey at ...

    Authors: Ataur Rahman Bhuiyan, Emdadul Haque Chowdhury, Olivier Kwiatek, Rokshana Parvin, Mushfiqur M Rahman, Mohammad R Islam, Emmanuel Albina and Geneviève Libeau
    Citation: BMC Veterinary Research 2014 10:247
  40. Regional anaesthetic techniques have been used in combination with systemic analgesics during small animal surgery to provide multimodal analgesia. Brachial plexus nerves block using local anaesthetics provide...

    Authors: Peter Kimeli, Eddy M Mogoa, Willy E Mwangi, Ambrose N Kipyegon, Gilbert Kirui, Daniel W Muasya, John D Mande, Edward Kariuki and Dominic Mijele
    Citation: BMC Veterinary Research 2014 10:249
  41. Bovine Neonatal Pancytopenia (BNP) is a disease of calves characterised by bone marrow trilineage hypoplasia, mediated by ingestion of alloantibodies in colostrum. Suspected subclinical forms of BNP have been ...

    Authors: Charlotte R Bell, Morag G Kerr, Philip R Scott, W Ivan Morrison and Helen Brown
    Citation: BMC Veterinary Research 2014 10:245
  42. Concern has been raised regarding the potential contributions of veterinary antimicrobial use to increasing levels of resistance in bacteria critically important to human health. Canine pyoderma is a frequent,...

    Authors: Jennifer F Summers, Anke Hendricks and David C Brodbelt
    Citation: BMC Veterinary Research 2014 10:240
  43. Thymidine kinase 1 (TK1) is a deoxyribonucleic acid (DNA) precursor enzyme and a proliferation biomarker used for prognosis and treatment monitoring of breast cancer in humans. The aim was to determine if seru...

    Authors: Kiran Kumar Jagarlamudi, Sara Westberg, Henrik Rönnberg and Staffan Eriksson
    Citation: BMC Veterinary Research 2014 10:228
  44. Mastitis is still considered to be the most economically important infectious disease in dairy cattle breeding. The immune response in mammary gland tissues could help in developing support strategies to comba...

    Authors: Ewa M Kościuczuk, Paweł Lisowski, Justyna Jarczak, Józef Krzyżewski, Lech Zwierzchowski and Emilia Bagnicka
    Citation: BMC Veterinary Research 2014 10:246
  45. Taenia solium is a zoonotic helminth with the potential to cause life threatening epilepsy in people through the aberrant larval infection of the brain called Neurocysticercosis (NCC). The pig is the intermediate...

    Authors: Zachary Nsadha, Lian F Thomas, Eric M Févre, George Nasinyama, Lonzy Ojok and Charles Waiswa
    Citation: BMC Veterinary Research 2014 10:239
  46. Atypical bovine spongiform encephalopathies (BSEs), classified as H-type and L-type BSE based on the Western immunoblot profiles, are naturally occurring diseases in cattle, which are phenotypically different ...

    Authors: Timm Konold, Laura J Phelan, Derek Clifford, Melanie J Chaplin, Saira Cawthraw, Michael J Stack and Marion M Simmons
    Citation: BMC Veterinary Research 2014 10:243
  47. Following infection and initial multiplication in the gut lumen, Salmonella Typhimurium crosses the intestinal epithelial barrier and comes into contact with cells of the host immune system. Mononuclear phagocyte...

    Authors: Kamila Kyrova, Hana Stepanova, Ivan Rychlik, Ondrej Polansky, Lenka Leva, Zuzana Sekelova, Martin Faldyna and Jiri Volf
    Citation: BMC Veterinary Research 2014 10:244
  48. The intensive use of anthelmintics for the control of helminthic infections has resulted in the development of anthelmintic resistance, which has become a major practical problem in many countries. A variety o...

    Authors: Michaela Dolinská, Oksana Ivanišinová, Alžbeta Königová and Marián Várady
    Citation: BMC Veterinary Research 2014 10:233

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