Egenvall A, Bonnett BN, Ohagen P, Olson P, Hedhammar A, von Euler H: Incidence of and survival after mammary tumors in a population of over 80,000 insured female dogs in Sweden from 1995 to 2002. Prev Vet Med. 2005, 69: 109-127. 10.1016/j.prevetmed.2005.01.014.
Article
PubMed
Google Scholar
Sleeckx N, De rooster H, Veldhuis Kroeze EJB, Van Ginneken C, Van Brantegem L: Canine mammary Tumors, an overview. Reprod Dom Anim. 2011, 46: 1112-1131. 10.1111/j.1439-0531.2011.01816.x.
Article
CAS
Google Scholar
Hellmen E, Bergstrom R, Holmberg L, Spangberg IB, Hansson K, Lindgren A: Prognostic factors in canine mammary tumors: a multivariate study of 202 consecutive cases. Vet Pathol. 1993, 30: 20-27. 10.1177/030098589303000103.
Article
CAS
PubMed
Google Scholar
Chang SC, Chang CC, Chang TJ, Wong ML: Prognostic factors associated with survival two years after surgery in dogs with malignant mammary tumors: 79 cases (1998–2002). J Am Vet Med Assoc. 2005, 227: 1625-1629. 10.2460/javma.2005.227.1625.
Article
PubMed
Google Scholar
MacEwen EG, Withrow S, Ch 27: Tumors of the mammary gland. In Small Animal Clinical Oncology. 5th edition. Philadelphia: Saunders Company; 2013:538–556.
Google Scholar
Schneider R: Comparison of age, sex, and incidence rates in human and canine breast cancer. Cancer. 1970, 26: 419-426. 10.1002/1097-0142(197008)26:2<419::AID-CNCR2820260225>3.0.CO;2-U.
Article
CAS
PubMed
Google Scholar
Young JL JR, Ward KC, Wingo PA, Howe HL: The incidence of malignant non-carcinomas of the female breast. Cancer Causes Control. 2004, 15: 313-319. 10.1023/B:CACO.0000024224.70386.d1.
Article
PubMed
Google Scholar
Bostock DE: Canine and feline mammary neoplasms. Br Vet J. 1986, 142: 506-515. 10.1016/0007-1935(86)90107-7.
Article
CAS
PubMed
Google Scholar
Rivera P, Melin M, Biagi T, Fall T, Haggstrom J, Lindblad-Toh K, Von Euler H: Mammary tumor development in dogs is associated with BRCA1 and BRCA2. Cancer Res. 2009, 69: 8770-8774. 10.1158/0008-5472.CAN-09-1725.
Article
CAS
PubMed
Google Scholar
King MC, Marks JH, Mandell JB: Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2. Science. 2003, 302: 643-646. 10.1126/science.1088759.
Article
CAS
PubMed
Google Scholar
Eisen A, Lubinski J, Klijn J, Moller P, Lynch HT, Offit K, Weber B, Rebbeck T, Neuhausen SL, Ghadirian P, Foulkes WD, Gershoni-Baruch R, Friedman E, Rennert G, Wagner T, Isaacs C, Kim-Sing C, Ainsworth P, Sun P, Narod SA: Breast cancer risk following bilateral oophorectomy in BRCA1 and BRCA2 mutation carriers: an international case-control study. J Clin Oncol. 2005, 23: 7491-7496. 10.1200/JCO.2004.00.7138.
Article
PubMed
Google Scholar
Stoppa-Lyonnet D, Ansquer Y, Dreyfus H, Gautier C, Gauthier-Villars M, Bourstyn E, Clough KB, Magdelenat H, Pouillart P, Vincent-Salomom A, Fourguet A, Asselain B: Familial invasive breast cancers: worse outcome related to BRCA1 mutations. J Clin Oncol. 2000, 18: 4053-4059.
CAS
PubMed
Google Scholar
Eerola H, Vahteristo P, Sarantaus L, Kyyrönen P, Pyrhönen S, Blomqvist C, Pukkala E, Nevanlinna H, Sannkila R: Survival of breast cancer patients in BRCA1, BRCA2 and non-BRCA1/2 breast cancer families: a relative survival analysis from finland. Int J Cancer. 2001, 93: 368-372. 10.1002/ijc.1341.
Article
CAS
PubMed
Google Scholar
Goffine JR, Chappuis PO, Begin LR, Wong N, Brunet JS, Hamel N, Paradis AJ, Boyd J, Foulkes WD: Impact of BRCA1 mutations and over expression of p53 on prognosis and response to treatment following breast carcinoma: 10-year follow up data. Cancer. 2003, 97: 527-536. 10.1002/cncr.11080.
Article
Google Scholar
Robson ME, Chappuis PO, Satagopan J, Wong N, Boyd J, Goffin JR, Hudis C, Roberge D, Norton L, Begin LR, Offit K, Foulkes WD: A combined analysis of out come folowing breast cancer: differences in survival based on BRCA1/BRCA2 mutation status and adminstration of adjuvant treatment. Breast Cancer Res. 2004, 6: R8-R17. 10.1186/bcr658.
Article
PubMed Central
CAS
PubMed
Google Scholar
Foulkes WD: Clinically relevant biology of hereditary breast cancer. Semin Oncol. 2007, 34 (5): 379-383. 10.1053/j.seminoncol.2007.07.010.
Article
CAS
PubMed
Google Scholar
Klopfleisch R, Gruber AD: Increased expression of BRCA2 and RAD51 in lymph node metastases of canine mammary adenocarcinomas. Vet Pathol. 2009, 46 (3): 416-422. 10.1354/vp.08-VP-0212-K-FL.
Article
CAS
PubMed
Google Scholar
von Euler H: Tumors of the mammary glands. In 3rd ed of the British Small Animal Veterinary Association (BSAVA) Manual of Canine and Feline Oncology, Volume 16. Edited by Dobson JM, Lascelles BDX. ; 1996:237–247.
Google Scholar
Lavelle GE, De Campos CB, Bertagnolli AC, Cassali GD: Canine malignant mammary gland neoplasms with advanced clinical staging treated with carboplatin and cyclooxygenase inhibitors. In Vivo. 2012, 26 (3): 375-379.
Google Scholar
Betz D, Schoenrock D, Mischke R, Baumgärtner W, Nolte I: Postoperative treatment outcome in canine mammary tumors: Multivariate analysis of the prognostic value of pre- and postoperatively available information. Tierärztl Prax Ausg K Kleintiere Heimtiere. 2012, 40 (4): 235-242. [Article in English, German]
CAS
PubMed
Google Scholar
Guadagni F, Ferroni P, Carlini S, Mariotti S, Spila A, Aloe S, D’Alessandro R, Carone DM, Cicchetti A, Riccitti A, Venturo I, Perri P, Filippo FD, Cognetti F, Botti C, Roselli M: A reevaluation of carcinoembryonic antigen CEA as a serum marker for breast cancer: a prospective longitudinal study. Clin Cancer Res. 2001, 7: 2357-2362.
CAS
PubMed
Google Scholar
Ali SM, Leitzel K, Chinchilli VM, Engle L, Demers L, Harvey HA, Carney W, Allard JM, Lioton A: Relationship of serum HER-2/neu and serum CA 15–3 on patients with metastatic breast cancer. Clin Chem. 2002, 48: 1314-1320.
CAS
PubMed
Google Scholar
Novaro V, Radisky DC, Castro NE, Weisz A, Bissell MJ: Malignant mammary cells acquire independence from extracellular context for regulation of estrogen receptor alpha. Clin Cancer Res. 2004, 10: 402-409. 10.1158/1078-0432.CCR-031209.
Article
Google Scholar
He Q, Fornander T, Johansson H, Johansson U, Hu GZ, Rutqvis LE, Skog S: Thymidine kinase 1 in serum predicts increased risk of distant or loco-regional recurrence following surgery in patients with early breast cancer. Anti Cancer Res. 2006, 26: 4753-4759.
CAS
Google Scholar
Chang CC, Tsai MH, Liao JW, Chan JP, Wong ML, Chang SC: Evaluation of hormone receptor expression for use in predicting survival of female dogs with malignant mammary gland tumors. J Am Vet Med Assoc. 2009, 235: 391-396. 10.2460/javma.235.4.391.
Article
CAS
PubMed
Google Scholar
Hsu WL, Huang HM, Liao JW, Wong ML, Chang SC: Increased survival in dogs with malignant mammary tumours overexpressing HER-2 protein and detection of a silent single nucleotide polymorphism in the canine HER-2 gene. Vet J. 2009, 180: 116-123. 10.1016/j.tvjl.2007.10.013.
Article
CAS
PubMed
Google Scholar
Campos LC, Lavalle GE, Estrela-Lima A, JC M dF, Guimaraes JE, Dutra AP, Ferreira E, de Sousa LP, Rabelo EML, AFD V dC, Cassali GD: CA 15.3, CEA and LDH in dogs with malignant mammary tumors. J Vet Intern Med. 2012, 26: 1383-1388. 10.1111/j.1939-1676.2012.01014.x.
Article
CAS
PubMed
Google Scholar
Eriksson S, Munch-Petersen B, Johansson K, Eklund H: Structure and function of cellular deoxyribonucleoside kinases. Cell Mol Life Sci. 2002, 59: 1327-1346. 10.1007/s00018-002-8511-x.
Article
CAS
PubMed
Google Scholar
Sherley JL, Kelly TJ: Regulation of human thymidine kinase during the cell cycle. J Biol Chem. 1988, 263: 8350-8358.
CAS
PubMed
Google Scholar
Von Euler H, Eriksson S: Comparative aspects of the proliferation marker thymidne kinase 1in human and canine tumor diseases. Vet Comp Oncol. 2011, 9: 1-15. 10.1111/j.1476-5829.2010.00238.x.
Article
CAS
PubMed
Google Scholar
Gronowitz JS, Hagberg H, Kallander CF, Simonsson B: The use of serum deoxythymidine kinase as a prognostic marker, and in the monitoring of patients with non-Hodgkin's lymphoma. Br J Cancer. 1983, 47: 487-495. 10.1038/bjc.1983.78.
Article
PubMed Central
CAS
PubMed
Google Scholar
Hallek M, Langenmayer I, Nerl C, Knauf W, Dietzfelbinger H, Adorf D, Ostwald M, Busch R, Kuhn-Hallek I, Thiel E, Emmerich B: Elevated serum thymidine kinase levels identify a subgroup at high risk of disease progression in early, nonsmoldering chronic lymphocytic leukemia. Blood. 1996, 93: 1732-1737.
Google Scholar
O'Neill KL, Zhang F, Li H, Fuja DG, Murray BK: Thymidine kinase 1 ± A prognostic and diagnostic indicator in ALL and AML patients. Leukemia. 2007, 21: 560-563. 10.1038/sj.leu.2404536.
Article
PubMed
Google Scholar
Von Euler H, Einarsson R, Olsson U, Lagerstedt AS, Eriksson S: Serum thymidine kinase activity in dogs with malignant lymphoma: a potent marker for prognosis and monitoring the disease. J Vet Int Med. 2004, 18: 696-702. 10.1111/j.1939-1676.2004.tb02608.x.
Article
Google Scholar
Von Euler H, Rivera P, Aronsson AC, Bengtsson C, Hansson LO, Eriksson S: Monitoring therapy in canine malignant lymphoma and leukemia with serum thymidine kinase 1 activity ± evaluation of a new, fully automated non-radiometric assay. Int J Oncol. 2009, 34: 505-510.
CAS
PubMed
Google Scholar
Sharif H, Von Euler H, Westberg S, He E, Wang L, Eriksson S: A sensitive and kinetically defined radiochemical assay for canine and human serum thymidine kinase 1 (TK1) to monitor canine malignant lymphoma. Vet J. 2012, 194: 40-47. 10.1016/j.tvjl.2012.03.006.
Article
CAS
PubMed
Google Scholar
Kiran Kumar J, Sharif H, Westberg S, Von Euler H, Eriksson S: High levels of inactive thymidine kinase 1 polypeptide in sera from dogs with solid tumours by immunoaffinity methods: Implications for in vitro diagnostics. Vet J. 2013, 197 (3): 854-860. 10.1016/j.tvjl.2013.05.036.
Article
CAS
PubMed
Google Scholar
Hanan S, Jagarlamudi KK, Wang L, He E, Eriksson S: Quaternary structures of recombinant, cellular, and serum forms of Thymidine Kinase 1 from dogs and humans. BMC Biochem. 2012, 13: 12-10.1186/1471-2091-13-12.
Article
PubMed Central
PubMed
Google Scholar
Karlstrom AR, Neumuller M, Gronowitz JS, Kallander CF: Molecular forms in human serum of enzymes synthesizing DNA precursors and DNA. Mol Cell Biochem. 1990, 92: 23-35. 10.1007/BF00220716.
Article
CAS
PubMed
Google Scholar
He Q, Zou L, Zhang PA, Liu JX, Skog S, Fornander T: The clinical significance of thymidine kinase 1 measurement in serum of breast cancer patients using anti-TK1 antibody. Int J Biol Marker. 2000, 15: 139-146.
CAS
Google Scholar
Zhang F, Li H, Pendleton AR, Robison JG, Monson KO, Murray BK, O'Neill KL: Thymidine kinase 1 immunoassay: A potential marker for breast cancer. Cancer Detect Prev. 2001, 25: 8-15.
CAS
PubMed
Google Scholar
Klopfleisch R, Lenze D, Hummel M, Gruber AD: Metastatic canine carcinomas can be identified by gene expression profile that partly overlaps with human breast cancer profiles. BMC Cancer. 2010, 10: 618-10.1186/1471-2407-10-618. doi: 10.1186/1471-2407-10-618
Article
PubMed Central
CAS
PubMed
Google Scholar
Pawlowski KM, Maciejewski H, Dolka I, Mol JA, Motyl T, Krol M: Gene expression profiles in canine mammary carcinomas of various grades of malignancy. BMC Vet Res. 2013, 9: 78-10.1186/1746-6148-9-78. doi: 10.1186/1746-6148-9-78
Article
PubMed Central
PubMed
Google Scholar
Pawlowski KM, Maciejewski H, Majchrzak K, Dolka I, Mol JA, Motyl T, Krol M: Five markers useful for the distinction of canine mammary malignancy. BMC Vet Res. 2013, 9: 138-10.1186/1746-6148-9-138. doi: 10.1186/1746-6148-9-138
Article
PubMed Central
PubMed
Google Scholar
Munch-Petersen B: Differences in the kinetic properties of thymidine kinase isoenzymes in unstimulated and phytohemagglutinin-stimulated human lymphocytes. Mol Cell Biochem. 1984, 64: 173-185. 10.1007/BF00224774.
Article
CAS
PubMed
Google Scholar