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Table 2 Serum thymidine kinase 1 (sTK1) activity and protein levels in sera from dogs with mammary tumors

From: Properties of cellular and serum forms of thymidine kinase 1 (TK1) in dogs with acute lymphocytic leukemia (ALL) and canine mammary tumors (CMTs): implications for TK1 as a proliferation biomarker

     sTK1 activity sTK1 concentration
Number Breed Age (yrs) Diagnosis (pmol/min/mL) (ng/mL)
     (Mean±SD)a (Mean±SD)b
1 Field Spaniel 9 Mammary adenoma 0.8±0.04 26±4
2 Rhodesian Ridgeback 11 Mammary adenoma 0.9±0.03 26±5
3 Rhodesian Ridgeback 3 Mammary adenoma 0.6±0.02 23±3
4 Boxer 13 Mammary carcinoma 0.9±0.04 27±2
5 American Cocker Spaniel 11 Mammary carcinoma 0.9±0.05 27±5
6 Boxer 9 Mammary carcinoma 0.6±0.03 21±4
7 Welsh Springer Spaniel 9 Mammary carcinoma 1.6±0.11 54±8
8 English Springer Spaniel 10 Mammary adenoma 1.5±0.14 35±5
9 German Shepherd 7 Mammary carcinoma 0.7±0.03 23±3
10 Belgian Shepherd 9 UC 0.5±0.01 17±3
11 Riesenschnauzer 14 Mammary carcinoma 0.9±0.02 30±3
12 Boxer 11 Mammary adenoma 1.4±0.1 27±4
13 Boxer 7 Mammary carcinoma 1.2±0.15 31±5
14 Rottweiler 9 Mammary adenoma 0.5±0.02 12±3
15 German Shepherd 11 Mammary adenoma 0.8±0.03 39±6
16 Dachshund 9 Mammary carcinoma 0.9±0.04 49±5
17 Greyhound 12 UC 1.8±0.18 28±4
18 Rhodesian Ridgeback 11 Mammary adenoma 1.0±0.06 17±3
19 Rottweiler 10 Mammary adenoma 0.9±0.05 28±2
20 Boxer 8 UC 0.7±0.04 9±2
21 Rottweiler 10 Mammary carcinoma 0.9±0.04 40±8
22 Rottweiler 7 Mammary adenoma 0.7±0.05 18±5
23 German Shepherd 10 Mammary carcinoma 1.3±0.08 31±7
24 Golden Retriever 8 Mammary carcinoma 1.5±0.12 43±9
25 Flatcoated Retriever 6 Mammary adenoma 1.0±0.09 28±5
26 Mixed breed 6 Mammary carcinoma 1.1±0.08 49±10
27 Border Collie 14 Mammary carcinoma 1.6±0.14 13±4
  1. aMean values of three observations from a single measurement occasion. bMean values of two observations from two independent experiments. SD = standard deviation. Mammary tumors are classified as adenoma (benign), carcinoma (malignant), and UC = unclassified.