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  1. Strongylid nematode infections may negatively affect both animal health and welfare, with deleterious consequences for livestock productivity. Many farmers in recent decades have relied on anthelmintics as the...

    Authors: Jaroslav Vadlejch, Iveta Angela Kyriánová, Marián Várady and Johannes Charlier
    Citation: BMC Veterinary Research 2021 17:106
  2. Alpha-2u globulin nephropathy mainly shows toxicological pathology only in male rats induced by certain chemicals and drugs, such as levamisole (antiparasitic and anticancer drugs). Streptozotocin (STZ) is als...

    Authors: Kanchana Kengkoom, Wannee Angkhasirisap, Tapanee Kanjanapruthipong, Rongdej Tungtrakanpoung, Khwanchanok Tuentam, Naphatson Phansom and Sumate Ampawong
    Citation: BMC Veterinary Research 2021 17:105
  3. Domestic cats rarely develop hepatocellular carcinoma. The reason for the low prevalence is unknown. Reductions in hepatocellular ploidy have been associated with hepatic carcinogenesis. Recent work in mice ha...

    Authors: Jacqueline Post, Ingeborg M. Langohr, Cynthia R.L. Webster, Peter Mottram, Chin-Chi Liu and Andrea Johnston
    Citation: BMC Veterinary Research 2021 17:104
  4. Status epilepticus (SE) or prolonged epileptic seizure activity is a common neurological emergency with a high mortality rate and, if left untreated, can lead to irreversible cerebral damage and systemic compl...

    Authors: Marios Charalambous, Holger A. Volk, Luc Van Ham and Sofie F. M. Bhatti
    Citation: BMC Veterinary Research 2021 17:103
  5. In free-ranging reptile populations, bacterial, fungal, viral and parasitic pathogens may affect hosts through impairment in movements, thermoregulation, reproduction, survival, and population dynamics. The sp...

    Authors: Livio Galosi, Anna Rita Attili, Stefania Perrucci, Francesco C. Origgi, Adolfo Maria Tambella, Giacomo Rossi, Vincenzo Cuteri, Maira Napoleoni, Nicholas Aconiti Mandolini, Gianni Perugini and Victor J. T. Loehr
    Citation: BMC Veterinary Research 2021 17:102
  6. Magnetic resonance imaging (MRI) is the most versatile and informative imaging modality for the diagnosis of locomotor injuries in many animal species; however, veterinary literature describing the MRI of the ...

    Authors: Zakriya Ali Al Mohamad, Usama Hagag, Mohamed Gomaa Tawfiek and Ayman El Nahas
    Citation: BMC Veterinary Research 2021 17:101
  7. Chronic intermittent or persistent diarrhoea is a common condition in dogs and may be a reflex of gastrointestinal or non-gastrointestinal disorders. Besides diarrhoea, many athletes experience other gastroint...

    Authors: J. C. Alves, A. Santos, P. Jorge and A. Pitães
    Citation: BMC Veterinary Research 2021 17:100
  8. The horses’ backs are particularly exposed to overload and injuries due to direct contact with the saddle and the influence of e.g. the rider’s body weight. The maximal load for a horse’s back during riding ha...

    Authors: Malgorzata Masko, Marta Borowska, Malgorzata Domino, Tomasz Jasinski, Lukasz Zdrojkowski and Zdzislaw Gajewski
    Citation: BMC Veterinary Research 2021 17:99
  9. Ménétrier-like disease is a rare hypertrophic canine gastropathy, reported in only seven dogs. Clinical signs are vomiting, anorexia and weight loss. Macroscopically, giant cerebriform gastric mucosal folds ar...

    Authors: E. Lagerstedt, T. Spillmann, N. Airas, L. Solano-Gallego and S. Kilpinen
    Citation: BMC Veterinary Research 2021 17:98
  10. Lipopolysaccharides (LPS) derived from gram-negative bacterial are often regarded as primary inducer of bovine mammary inflammation. This study evaluated the biological response of metformin activated AMPK sig...

    Authors: Tianle Xu, Xinyue Wu, Xubin Lu, Yusheng Liang, Yongjiang Mao, Juan J. Loor and Zhangping Yang
    Citation: BMC Veterinary Research 2021 17:97
  11. Mesenchymal stem cells (MSCs) have generated a great amount of interest in recent years as a novel therapeutic application for improving the quality of pet life and helping them free from painful conditions an...

    Authors: Huina Luo, Dongsheng Li, Zhisheng Chen, Bingyun Wang and Shengfeng Chen
    Citation: BMC Veterinary Research 2021 17:96
  12. Brucellosis is a contagious zoonotic disease of great public health and economic significance especially in developing countries. The disease affects humans and several species of livestock and wildlife. Studi...

    Authors: Robert Aruho, Ewan T. MacLeod, Leonard Manirakiza and Innocent B. Rwego
    Citation: BMC Veterinary Research 2021 17:95
  13. Trichinellosis, caused by Trichinella spiralis, is a serious foodborne parasitic zoonosis. Tibetan pig is an infrequent, endemic plateau pig species, mainly distributed in Tibet Plateau, China. Because of the fre...

    Authors: Li Tingting, Li Wenhui, Zhang Nianzhang, Qu Zigang, John A Ohiolei, Li Li, Yan Hongbin, Jia Wanzhong and Fu Baoquan
    Citation: BMC Veterinary Research 2021 17:94
  14. Animal vaccination is an important way to stop the spread of diseases causing immense damage to livestock and economic losses and the potential transmission to humans. Therefore effective method for vaccine pr...

    Authors: Halima Rhazi, Najete Safini, Karima Mikou, Meryeme Alhyane, Khalid Omari Tadlaoui, Xiangliang Lin, Nandini P. Venkatesan and Mehdi Elharrak
    Citation: BMC Veterinary Research 2021 17:93
  15. Between February and April 2016, a slight increase in mortality was observed in a colony consisting of 400 captive Seba’s short-tailed bats (Carollia perspicillata). These animals cohabited with other nocturnal a...

    Authors: K. Hahn, I. B. Veiga, M. Schediwy, D. Wiederkehr, M. Meniri, M. Schneeberger, P. Rüegg-van den Broek, C. Gurtner, N. J. Fasel, S. Kittl, M. Fredriksson-Ahomaa, S. Schmitt and N. Stokar-Regenscheit
    Citation: BMC Veterinary Research 2021 17:92
  16. Ticks transmit several diseases that result in high morbidity and mortality in livestock. Tick-borne diseases are an economic burden that negatively affect livestock production, cost countries billions of doll...

    Authors: Munyaradzi Davis Shekede, Silvester Maravanyika Chikerema, Moregood Spargo, Isaiah Gwitira, Samuel Kusangaya, Aldridge Nyasha Mazhindu and Daud Nyosi Ndhlovu
    Citation: BMC Veterinary Research 2021 17:91
  17. While a necessary step toward enhancing rigor and reproducibility of veterinary clinical trials conducted on the translational spectrum includes understanding the current state of the field, no broad assessmen...

    Authors: Sarah A. Moore, Angela McCleary-Wheeler, Joan R Coates, Natasha Olby and Cheryl London
    Citation: BMC Veterinary Research 2021 17:90
  18. Prior studies have suggested that pimobendan is associated with several positive effects in cats, including improved survival in cats with congestive heart failure and improved left atrial function in research...

    Authors: Maureen S. Oldach, Yu Ueda, Eric S. Ontiveros, Samantha L. Fousse, Lance C. Visser and Joshua A. Stern
    Citation: BMC Veterinary Research 2021 17:89
  19. Porcine reproductive and respiratory syndrome (PRRS) is a threat to pig production worldwide. Our objective was to understand mechanisms of persistence of PRRS virus (PRRSV) in tonsil. Transcriptome data from ...

    Authors: Qian Dong, Joan K. Lunney, Kyu-Sang Lim, Yet Nguyen, Andrew S. Hess, Hamid Beiki, Raymond R. R. Rowland, Kristen Walker, James M. Reecy, Christopher K. Tuggle and Jack C. M. Dekkers
    Citation: BMC Veterinary Research 2021 17:88
  20. Bovine Viral Diarrhea virus (BVDV) is one of important diseases of cattle worldwide causing economic losses to the cattle industry primarily due to increased premature culling and decreased reproductive perfor...

    Authors: Erdachew Yitagesu, Wendi Jackson, Nigatu Kebede, Woutrina Smith and Tsegaw Fentie
    Citation: BMC Veterinary Research 2021 17:87
  21. The discovery of the superbug mcr-1-positive Escherichia coli (MCRPEC) has drew greet attention. Swine-origin multi-drug resistant MCRPEC has been a potential threat to public health and safety. However, there we...

    Authors: Jingzhi Yuan, Xiaoye Wang, Dali Shi, Qiang Ge, Xingxing Song, Wen Hu, Deyuan Wei, Chenling Ge, Xun Li and Chuanhuo Hu
    Citation: BMC Veterinary Research 2021 17:86
  22. Lymphocytic neoplasms with frequent reactive lymphocytes are uncommonly reported in dogs, and can pose a diagnostic challenge. Different diagnostic modalities such as cytology, flow cytometry, histopathology, ...

    Authors: Gary Kwok Cheong Lee, Dorothee Bienzle, Stefan Matthias Keller, Mei-Hua Hwang, Nikos Darzentas, Haiyang Chang, Emily Rätsep, Rebecca Egan and Janet Beeler-Marfisi
    Citation: BMC Veterinary Research 2021 17:85
  23. Osteosarcoma is a malignant mesenchymal bone tumor. Although it is a common tumor in the appendicular skeleton of dogs and cats, it is rarely reported in birds. Retroviruses are usually associated with solid t...

    Authors: Jefferson Bruno Soares Oliveira, Ayisa Rodrigues de Oliveira, Daniel Oliveira dos Santos, Thaynara Parente de Carvalho, Larissa Giannini Alves Moreira, Herlandes Penha Tinoco, Carlyle Mendes Coelho, Hannah Luiza Gonsalves Coelho, Maria Clara de Paiva Zucherato, Sandra Yuliet Marín-Gómez, Camila Siqueira Costa, Nelson R. S. Martins and Renato Lima Santos
    Citation: BMC Veterinary Research 2021 17:84
  24. Harmonized institutional processes and reviewer training are vital to maintain integrity and ethical rigor of the veterinary clinical research pipeline and are a prerequisite to future work that might establis...

    Authors: S. A. Moore, A. O’Kell, H. Borghese, R. Garabed, H. O’Meara and P. Baneux
    Citation: BMC Veterinary Research 2021 17:83
  25. Respiratory diseases are among the most important factors affecting swine farm productivity in Canada. The objectives of this study were to investigate antibody responses to porcine reproductive and respirator...

    Authors: Elana Raaphorst, Abdolvahab Farzan, Robert M. Friendship and Brandon N. Lillie
    Citation: BMC Veterinary Research 2021 17:82
  26. Although dogs are a commonly owned companion animal in the UK, the species experiences many health problems that are predictable from demographic information. This study aimed to use anonymised veterinary clin...

    Authors: Dan G. O’Neill, Hannah James, Dave C. Brodbelt, David B. Church and Camilla Pegram
    Citation: BMC Veterinary Research 2021 17:69
  27. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Rebecca Ricci, Daniele Conficoni, Giada Morelli, Carmen Losasso, Leonardo Alberghini, Valerio Giaccone, Antonia Ricci and Igino Andrighetto
    Citation: BMC Veterinary Research 2021 17:81

    The original article was published in BMC Veterinary Research 2018 14:209

  28. Genotype S H9N2 viruses have become predominant in poultry in China since 2010. These viruses frequently donate their whole internal gene segments to other emerging influenza A subtypes such as the novel H7N9,...

    Authors: Xiuli Li, Min Gu, Xiaoquan Wang, Ruyi Gao, Xinxin Bu, Xiaoli Hao, Jing Ma, Jiao Hu, Shunlin Hu, Xiaowen Liu, Sujuan Chen, Daxin Peng, Xinan Jiao and Xiufan Liu
    Citation: BMC Veterinary Research 2021 17:80
  29. Livestock play an important role as reservoir of enteric pathogens and antimicrobial resistance (AMR), a health and economic concern worldwide. However, little is known regarding the transmission and maintenan...

    Authors: Johan Espunyes, Oscar Cabezón, Andrea Dias-Alves, Pol Miralles, Teresa Ayats and Marta Cerdà-Cuéllar
    Citation: BMC Veterinary Research 2021 17:79
  30. Proxies are mathematical calculations based on fasting glucose and/or insulin concentrations developed to allow prediction of insulin sensitivity (IS) and β-cell response. These proxies have not been evaluated...

    Authors: Sanna Lindåse, Katarina Nostell, Peter Bergsten, Anders Forslund and Johan Bröjer
    Citation: BMC Veterinary Research 2021 17:78
  31. In humans, the drug metabolizing enzyme CYP2D6 is highly polymorphic resulting in substantial differences in the metabolism of drugs including anti-arrhythmics, neuroleptics, and opioids. The objective of this...

    Authors: S. R. Gretler, C. J. Finno, P. H. Kass and H. K. Knych
    Citation: BMC Veterinary Research 2021 17:77
  32. French bulldogs exhibit significantly larger femoral external rotation and abduction than other breeds. We were curious as to whether this peculiar leg kinematic affects patellar motion and/or might induce med...

    Authors: Silvia V. Lehmann, Emanuel Andrada, Roxana Taszus, Daniel Koch and Martin S. Fischer
    Citation: BMC Veterinary Research 2021 17:76
  33. Respiratory diseases are the second most common cause of illnesses in horses, their etiology can be viral, bacterial, immune-mediated, or mechanical (Racklyeft and Love DN, Aust Vet J 78:549–59, 2000; Austin e...

    Authors: Elisabetta Mondo, Riccardo Rinnovati, Alessandro Spadari, Federica Giacometti, Andrea Serraino, Federica Savini and Silvia Piva
    Citation: BMC Veterinary Research 2021 17:75
  34. Marigold (Tagetes erecta L) accounts for over half of the world’s loose flower production, and marigold crop residue (MCR) are abundantly available and should be used as a forage. In this study, MCR from the last...

    Authors: Zhijiang Hou, Jianyong Liu, Ming Cai, Yanpei Liu, Lan Mu, Yuee Gao, Metha Wanapat and Bizhi Huang
    Citation: BMC Veterinary Research 2021 17:74
  35. Ureteral atresia is the congenital absence of a ureteral opening, resulting in a blind-ended ureter that fails to terminate at the urinary bladder. Consequently, severe hydroureter and hydronephrosis occur ips...

    Authors: Megan Zalek, Rohan Shah and Timothy Bolton
    Citation: BMC Veterinary Research 2021 17:73
  36. Streptococcus suis is an important pathogen that causes severe diseases mostly in weaned piglets. Only available vaccines in the field are those composed of killed bacteria (bacterins) but data about their effect...

    Authors: Lorelei Corsaut, Léa Martelet, Guillaume Goyette-Desjardins, Guy Beauchamp, Martine Denicourt, Marcelo Gottschalk and Mariela Segura
    Citation: BMC Veterinary Research 2021 17:72
  37. In dogs with atopic dermatitis, intradermal testing (IDT) or allergen specific IgE serological testing are routinely employed to identify causative allergens. These allergens can then be used for allergen-spec...

    Authors: N. Khantavee, C. Chanthick, A. Tungtrongchitr, N. Techakriengkrai, S. Suradhat, N. Sookrung, S. Roytrakul and N. Prapasarakul
    Citation: BMC Veterinary Research 2021 17:71
  38. Among the 6–8 million animals that enter the rescue shelters every year, nearly 3–4 million (i.e., 50% of the incoming animals) are euthanized, and 10–25% of them are put to death specifically because of shelt...

    Authors: Janae Bradley and Suchithra Rajendran
    Citation: BMC Veterinary Research 2021 17:70
  39. The effects of safflower oil and vitamin C (Vit. C) inclusion in broiler chicken diets on the growth performance, apparent ileal digestibility coefficient “AID%” of amino acids, intestinal histology, behavior,...

    Authors: Shimaa A. Amer, Wafaa A. M. Mohamed, Heba S. A. Gharib, Naif A. Al-Gabri, Ahmed Gouda, Mohamed Tharwat Elabbasy, Ghada I. Abd El-Rahman and Anaam E. Omar
    Citation: BMC Veterinary Research 2021 17:68
  40. Umbilical vein bacterial infections may cause liver abscesses during bacterial ascent. A single liver abscess can be surgically treated by marsupialization, but a risk of recurrence or non-healing remains. Mor...

    Authors: Reiichiro Sato, Kazutaka Yamada, Taiki Yokoyama, Koki Tanimoto, Shoko Takeuchi, Natsumi Tatsuzawa, Shiho Nakui, Hiroyuki Satoh, Mahmoud Fadul and Adrian Steiner
    Citation: BMC Veterinary Research 2021 17:67
  41. Bovine viral diarrhea virus (BVDV) is an important global viral pathogen of cattle and other ruminants. To survey the infection rate and genetic diversity of BVDV in western China, a total of 1234 serum sample...

    Authors: Lingling Chang, Yanping Qi, Dan Liu, Qian Du, Xiaomin Zhao and Dewen Tong
    Citation: BMC Veterinary Research 2021 17:66
  42. Enterocytozoon hepatopenaei (EHP) is an enteric pathogen that affects Penaeus vannamei and Penaeus monodon shrimp in many SE Asian countries. In the western hemisphere, EHP was reported for the first time in 2016...

    Authors: L. F. Aranguren Caro, F. Alghamdi, K. De Belder, J. Lin, H. N. Mai, J. Millabas, Y. Alrehaili, A. Alazwari, S. Algetham and A. K. Dhar
    Citation: BMC Veterinary Research 2021 17:65
  43. H7 subtype avian influenza has caused great concern in the global poultry industry and public health. The conventional serological subtype-specific diagnostics is implemented by hemagglutination inhibition (HI...

    Authors: Yuan Li, Hongliu Ye, Meng Liu, Suquan Song, Jin Chen, Wangkun Cheng and Liping Yan
    Citation: BMC Veterinary Research 2021 17:64
  44. Foot-and-mouth disease (FMD) is a highly infectious viral disease, recognised to affect animals in the order Artiodactyla. The disease is rarely fatal in adult animals, however high mortality is associated wit...

    Authors: Ryan A. Waters, Jemma Wadsworth, Valerie Mioulet, Andrew E. Shaw, Nick J. Knowles, Darab Abdollahi, Reza Hassanzadeh, Keith Sumption and Donald P. King
    Citation: BMC Veterinary Research 2021 17:63
  45. Increasing evidence suggests that nutritional manipulation of the commensal gut microbiota (GM) may play a key role in maintaining animal health and production in an era of reduced antimicrobial usage. Gastroi...

    Authors: Andrew R. Williams, Laura J. Myhill, Sophie Stolzenbach, Peter Nejsum, Helena Mejer, Dennis S. Nielsen and Stig M. Thamsborg
    Citation: BMC Veterinary Research 2021 17:62
  46. Lumpy skin disease (LSD) is a contagious viral disease of cattle caused by lumpy skin disease virus (LSDV). LSD has recently spread in Asia following outbreaks in the Middle East and Europe. The disease emerge...

    Authors: Shukes Chandra Badhy, Mohammad Golam Azam Chowdhury, Tirumala Bharani Kumar Settypalli, Giovanni Cattoli, Charles Euloge Lamien, Mohammad Aflak Uddin Fakir, Shamima Akter, Mozaffar Goni Osmani, Faisol Talukdar, Noorjahan Begum, Izhar Ahmed Khan, Md Bazlur Rashid and Mohammad Sadekuzzaman
    Citation: BMC Veterinary Research 2021 17:61
  47. Canine cognitive dysfunction syndrome (CCDS) is a progressive neurodegenerative disorder found in senior dogs. Due to the lack of biological markers, CCDS is commonly underdiagnosed. The aim of this study was ...

    Authors: Sataporn Phochantachinda, Boonrat Chantong, Onrapak Reamtong and Duangthip Chatchaisak
    Citation: BMC Veterinary Research 2021 17:60
  48. Information obtained from abattoirs on the causes of liver condemnation is important in preventing the spread of diseases and for promoting food security. The current study reviews three years (2009 to 2011) p...

    Authors: Darien Kheder Ali Mohamed
    Citation: BMC Veterinary Research 2021 17:58

    The Correction to this article has been published in BMC Veterinary Research 2021 17:298

  49. Infectious disease, particularly the fungal disease chytridiomycosis (caused by Batrachochytrium dendrobatidis), is a primary cause of amphibian declines and extinctions worldwide. The transdermal route, although...

    Authors: Victoria K. Llewelyn, Lee Berger and Beverley D. Glass
    Citation: BMC Veterinary Research 2021 17:57

    The Correction to this article has been published in BMC Veterinary Research 2021 17:161

  50. Mandibular masses caused by inflammatory processes due to bacterial infections, most common with Actinomyces bovis, are well known in herbivors. This case represents a rare differential diagnosis to common inflam...

    Authors: Svenja Hartung, Kernt Köhler, Christiane Herden and Manfred Henrich
    Citation: BMC Veterinary Research 2021 17:55

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