PDSA. PAW PDSA animal wellbeing report 2019. 2019.
Payne E, Bennett PC, McGreevy PD. Current perspectives on attachment and bonding in the dog-human dyad. Psychol Res Behav Manag. 2015;8:71–9.
Article
PubMed
PubMed Central
Google Scholar
Westgarth C, Christley RM, Jewell C, German AJ, Boddy LM, Christian HE. Dog owners are more likely to meet physical activity guidelines than people without a dog: An investigation of the association between dog ownership and physical activity levels in a UK community. Sci Rep. 2019;9(1):5704.
Article
PubMed
PubMed Central
CAS
Google Scholar
Endo K, Yamasaki S, Ando S, Kikusui T, Mogi K, Nagasawa M, et al. Dog and cat ownership predicts adolescents’ mental well-being: a population-based longitudinal study. Int J Environ Res Public Health. 2020;17(3):884.
Article
PubMed Central
Google Scholar
Zijlema WL, Christian H, Triguero-Mas M, Cirach M, van den Berg M, Maas J, et al. Dog ownership, the natural outdoor environment and health: a cross-sectional study. BMJ Open. 2019;9(5):e023000.
Article
PubMed
PubMed Central
Google Scholar
Hedhammar ÅA, Malm S, Bonnett B. International and collaborative strategies to enhance genetic health in purebred dogs. Vet J. 2011;189(2):189–96.
Article
PubMed
Google Scholar
O’Neill DG, Church DB, McGreevy PD, Thomson PC, Brodbelt DC. Prevalence of disorders recorded in dogs attending primary-care veterinary practices in England. PLoS ONE. 2014a;9(3):1–16.
Article
Google Scholar
Gough A, Thomas A, O’Neill D. Breed predispositions to disease in dogs and cats. 3rd ed. Chichester: Wiley-Blackwell; 2018. p. 398.
Book
Google Scholar
O’Neill DG, Keijser SFA, Hedhammar Å, Kisko C, Leroy G, Llewellyn-Zaidi A, et al. Moving from information and collaboration to action: report from the 3rd International Dog Health Workshop, Paris in April 2017. Canine Genet Epidemiol. 2017;4(1):16.
Article
PubMed
PubMed Central
Google Scholar
Bateson P. Independent inquiry into dog breeding. Cambridge: University of Cambridge; 2010. Available from: https://dogwellnet.com/files/file/308-independent-inquiry-into-dog-breeding-2010-patrick-bateson/.
McGreevy PD, Nicholas FW. Some practical solutions to welfare problems in dog breeding. Anim Welfare. 1999;8:329–41.
Article
Google Scholar
Collins LM, Asher L, Summers JF, Diesel G, McGreevy PD. Welfare epidemiology as a tool to assess the welfare impact of inherited defects on the pedigree dog population. Anim Welfare. 2010;19:67–75.
Article
CAS
Google Scholar
O’Neill D, Church D, McGreevy P, Thomson P, Brodbelt D. Approaches to canine health surveillance. Canine Genetics Epidemiology. 2014b;1(1):2.
Article
PubMed
PubMed Central
Google Scholar
Banfield Pet Hospital. What’s our BARK all about? Banfield applied research and knowledge: Banfield; 2020 [Available from: https://www.banfield.com/state-of-pet-health/the-bark-team/kirk-j-breuninger,-vmd,-mph.
Muellner P, Muellner U, Gates MC, Pearce T, Ahlstrom C, O'Neill D, et al. Evidence in practice – a pilot study leveraging companion animal and equine health data from primary care veterinary clinics in New Zealand. Front Vet Sci. 2016;3(116).
O’Neill DG, Turgoose E, Church DB, Brodbelt DC, Hendricks A. Juvenile-onset and adult-onset demodicosis in dogs in the UK: prevalence and breed associations. J Small Anim Pract. 2019;61(1):32–41.
Article
PubMed
PubMed Central
Google Scholar
Singleton DA, Noble PJM, Sánchez-Vizcaíno F, Dawson S, Pinchbeck GL, Williams NJ, et al. Pharmaceutical prescription in canine acute diarrhoea: a longitudinal electronic health record analysis of first opinion veterinary practices. Front Vet Sci. 2019;6(218).
Yoon S, Fleeman LM, Wilson BJ, Mansfield CS, McGreevy P. Epidemiological study of dogs with diabetes mellitus attending primary care veterinary clinics in Australia. Vet Rec. 2020;187(3):e22 vetrec-2019-105467.
Article
PubMed
Google Scholar
Keijser SFA, Vernooij JCM, van Garderen E, van Rooijen P, Fieten H, van Steenbeek FG, et al. Quantification of the health-status of the Dutch Labrador retriever population. Prev Vet Med. 2019;171:104764.
Article
CAS
PubMed
Google Scholar
Medivet M. VetCompass London: Medivet 2020 [Available from: https://www.medivet.co.uk/about-medivet/animal-welfare/vet-compass/.
Vets4Pets. Helping to reduce antibiotic over prescribing: Vets4Pets; 2019 [Available from: https://www.vets4pets.com/blogs/helping-to-reduce-antibiotic-over-prescribing/.
BWG. The Brachycephalic Working Group: The Brachycephalic Working Group; 2020 [Available from: http://www.ukbwg.org.uk/.
Royal Veterinary College. Brachycephalic Research Team: Royal Veterinary College; 2020 [Available from: https://www.rvc.ac.uk/research/focus/brachycephaly.
O’Neill DG, Darwent EC, Church DB, Brodbelt DC. Border Terriers under primary veterinary care in England: demography and disorders. Canine Genet Epidemiol. 2017;4(1):15.
Article
PubMed
PubMed Central
Google Scholar
O’Neill DG, Skipper AM, Kadhim J, Church DB, Brodbelt DC, Packer RMA. Disorders of Bulldogs under primary veterinary care in the UK in 2013. PLOS ONE. 2019;14(6):e0217928.
Article
PubMed
PubMed Central
CAS
Google Scholar
Summers J, O’Neill D, Church D, Thomson P, McGreevy P, Brodbelt D. Prevalence of disorders recorded in Cavalier King Charles Spaniels attending primary-care veterinary practices in England. Canine Genet Epidemiol. 2015;2(1):4.
Article
PubMed
PubMed Central
Google Scholar
O’Neill DG, Packer RMA, Lobb M, Church DB, Brodbelt DC, Pegram C. Demography and commonly recorded clinical conditions of Chihuahuas under primary veterinary care in the UK in 2016. BMC Vet Res. 2020;16(1):42.
Article
PubMed
PubMed Central
CAS
Google Scholar
O’Neill DG, Baral L, Church DB, Brodbelt DC, Packer RMA. Demography and disorders of the French Bulldog population under primary veterinary care in the UK in 2013. Canine Genet Epidemiol. 2018;5(1):3.
Article
PubMed
PubMed Central
Google Scholar
O’Neill D, Coulson NR, Church DB, Brodbelt DC. Demography and disorders of German Shepherd Dogs under primary veterinary care in the UK. Canine Genet Epidemiol. 2017;4(1):7.
Article
PubMed
PubMed Central
Google Scholar
O’Neill DG, Rooney NJ, Brock C, Church DB, Brodbelt DC, Pegram C. Greyhounds under general veterinary care in the UK during 2016: demography and common disorders. Canine Genet Epidemiol. 2019;6(1):4.
Article
PubMed
PubMed Central
Google Scholar
McGreevy PD, Wilson BJ, Mansfield CS, Brodbelt DC, Church DB, Dhand N, et al. Labrador retrievers under primary veterinary care in the UK: demography, mortality and disorders. Canine Genet Epidemiol. 2018;5(1):8.
Article
PubMed
PubMed Central
Google Scholar
O’Neill DG, Butcher C, Church DB, Brodbelt DC, Gough AG. Miniature Schnauzers under primary veterinary care in the UK in 2013: demography, mortality and disorders. Canine Genet Epidemiol. 2019;6(1):1.
Article
PubMed
PubMed Central
Google Scholar
O’Neill DG, Darwent EC, Church DB, Brodbelt DC. Demography and health of Pugs under primary veterinary care in England. Canine Genet Epidemiol. 2016;3(1):1–12.
Article
Google Scholar
O’Neill DG, Seah WY, Church DB, Brodbelt DC. Rottweilers under primary veterinary care in the UK: demography, mortality and disorders. Canine Genet Epidemiol. 2017;4(1):13.
Article
PubMed
PubMed Central
Google Scholar
O’Neill DG, Ballantyne ZF, Hendricks A, Church DB, Brodbelt DC, Pegram C. West Highland White Terriers under primary veterinary care in the UK in 2016: demography, mortality and disorders. Canine Genet Epidemiol. 2019;6(1):7.
Article
PubMed
PubMed Central
Google Scholar
Summers JF, O’Neill DG, Church D, Collins L, Sargan D, Brodbelt DC. Health-related welfare prioritisation of canine disorders using electronic health records in primary care practice in the UK. BMC Vet Res. 2019;15(1):163.
Article
PubMed
PubMed Central
Google Scholar
The Kennel Club. Breed health and conservation plans (BHCPs): The Kennel Club Limited; 2020 [Available from: https://www.thekennelclub.org.uk/health/breed-health-and-conservation-plans/.
O’Neill DG, Corah CH, Church DB, Brodbelt DC, Rutherford L. Lipoma in dogs under primary veterinary care in the UK: prevalence and breed associations. Canine Genet Epidemiol. 2018;5(1):9.
Article
PubMed
PubMed Central
Google Scholar
Kim E, Choe C, Yoo JG, Oh S-I, Jung Y, Cho A, et al. Major medical causes by breed and life stage for dogs presented at veterinary clinics in the Republic of Korea: a survey of electronic medical records. PeerJ. 2018;6:e5161.
Article
PubMed
PubMed Central
Google Scholar
Wiles BM, Llewellyn-Zaidi AM, Evans KM, O’Neill DG, Lewis TW. Large-scale survey to estimate the prevalence of disorders for 192 Kennel Club registered breeds. Canine Genet Epidemiol. 2017;4(1):8.
Article
CAS
PubMed
PubMed Central
Google Scholar
O’Neill DG, Brodbelt DC, Hodge R, Church DB, Meeson RL. Epidemiology and clinical management of elbow joint disease in dogs under primary veterinary care in the UK. Canine Med Genet. 2020;7(1):1.
Article
PubMed
PubMed Central
Google Scholar
Hall JL, Owen L, Riddell A, Church DB, Brodbelt DC, O’Neill DG. Urinary incontinence in male dogs under primary veterinary care in England: prevalence and risk factors. J Small Anim Pract. 2019;60(February):86–95.
Article
CAS
PubMed
Google Scholar
Pegram C, O’Neill DG, Church DB, Hall J, Owen L, Brodbelt DC. Spaying and urinary incontinence in bitches under UK primary veterinary care: a case–control study. J Small Anim Pract. 2019;60(7):395–403.
Article
CAS
PubMed
PubMed Central
Google Scholar
The Kennel Club. The Kennel Club Breed Health Improvement Strategy: A step-by-step guide. London: The Kennel Club; 2012.
Google Scholar
Buckland EL, Corr SA, Abeyesinghe SM, Wathes CM. Prioritisation of companion dog welfare issues using expert consensus. Anim Welfare. 2014;23(1):39–46.
Article
CAS
Google Scholar
Buckland EL, Whiting MC, Abeyesinghe SM, Asher L, Corr S, Wathes CM. A survey of stakeholders’ opinions on the priority issues affecting the welfare of companion dogs in Great Britain. Anim Welfare. 2013;22(2):239–53.
Article
CAS
Google Scholar
Kennedy N, Brodbelt DC, Church DB, O’Neill DG. Detecting false-positive disease references in veterinary clinical notes without manual annotations. npj Digit Med. 2019;2(1):33.
Article
PubMed
PubMed Central
Google Scholar
Egenvall A, Bonnett BN, Olson P, Hedhammar Å. Gender, age, breed and distribution of morbidity and mortality in insured dogs in Sweden during 1995 and 1996. Vet Rec. 2000;146(8):519–25.
Article
CAS
PubMed
Google Scholar
Egenvall A, Hedhammar A, Bonnett BN, Olson P. Gender, age and breed pattern of diagnoses for veterinary care in insured dogs in Sweden during 1996. Vet Rec. 2000;146(19):551–7.
Article
CAS
PubMed
Google Scholar
Freeman LM, Abood SK, Fascetti AJ, Fleeman LM, Michel KE, Laflamme DP, et al. Disease prevalence among dogs and cats in the United States and Australia and proportions of dogs and cats that receive therapeutic diets or dietary supplements. J Am Vet Med Assoc. 2006;229(4):531–4.
Article
PubMed
Google Scholar
O’Neill DG, Jackson C, Guy JH, Church DB, McGreevy PD, Thomson PC, et al. Epidemiological associations between brachycephaly and upper respiratory tract disorders in dogs attending veterinary practices in England. Canine Genet Epidemiol. 2015;2(1):10.
Article
PubMed
PubMed Central
Google Scholar
Pegram C, Wonham K, Brodbelt DC, Church DB, O’Neill DG. Staffordshire Bull Terriers in the UK: their disorder predispositions and protections. Canine Med Genet. 2020;7(1):13.
Article
PubMed Central
Google Scholar
Kirkwood JK. Selective breeding: making the welfare consequences clear. Vet Rec. 2012;170(21):535–7.
Article
PubMed
Google Scholar
Suttorp MM, Siegerink B, Jager KJ, Zoccali C, Dekker FW. Graphical presentation of confounding in directed acyclic graphs. Nephrol Dial Transplant. 2014;30(9):1418–23.
Article
PubMed
Google Scholar
Ward E, German AJ, Churchill JA. The global pet obesity initiative position statement. 2018.
Collins LM, Asher L, Summers J, McGreevy P. Getting priorities straight: risk assessment and decision-making in the improvement of inherited disorders in pedigree dogs. Vet J. 2011;189(2):147–54.
Article
PubMed
Google Scholar
Summers JF, Diesel G, Asher L, McGreevy PD, Collins LM. Inherited defects in pedigree dogs. Part 2: disorders that are not related to breed standards. Vet J. 2010;183(1):39–45.
Article
PubMed
Google Scholar
Asher L, Diesel G, Summers JF, McGreevy PD, Collins LM. Inherited defects in pedigree dogs. Part 1: disorders related to breed standards. Vet J. 2009;182(3):402–11.
Article
PubMed
Google Scholar
Jaarsma DADC, Dolmans DHJM, Scherpbier AJJA, Beukelen PV. Preparation for practice by Veterinary School: a comparison of the perceptions of alumni from a traditional and an innovative veterinary curriculum. J Vet Med Educ. 2008;35(3):431–8.
Article
PubMed
Google Scholar
Johnson J, Collins T, Degeling C, Fawcett A, Fisher AD, Freire R, et al. The first shared online curriculum resources for veterinary undergraduate learning and teaching in animal welfare and ethics in Australia and New Zealand. Animals. 2015;5(2):395–406.
Article
PubMed
PubMed Central
Google Scholar
Walsh DA, Osburn BI, Christopher MM. Defining the attributes expected of graduating veterinary medical students. J Am Vet Med Assoc. 2001;219(10):1358–65.
Article
CAS
PubMed
Google Scholar
Walsh DA, Osburn BI, Schumacher RL. Defining the attributes expected of graduating veterinary medical students, part 2: external evaluation and outcomes assessment. J Vet Med Educ. 2002;29(1):36–42.
Article
PubMed
Google Scholar
Lempp H, Seale C. The hidden curriculum in undergraduate medical education: qualitative study of medical students’ perceptions of teaching. BMJ. 2004;329(7469):770–3.
Article
PubMed
PubMed Central
Google Scholar
Baguley J. The role of final year extramural placements in the undergraduate veterinary curriculum. Aust Vet J. 2006;84(5):182–6.
Article
CAS
PubMed
Google Scholar
Pollard-Williams S, Doyle RE, Freire R. The influence of workplace learning on attitudes toward animal welfare in veterinary students. J Vet Med Educ. 2014;41(3):253–7.
Article
PubMed
Google Scholar
Fitzpatrick JL, Mellor DJ. Survey of the views of graduates (1993 to 1997) on the undergraduate veterinary clinical curriculum in the British Isles. Vet Rec. 2003;153(13):393.
Article
CAS
PubMed
Google Scholar
Powers DE. Student perceptions of the first year of Veterinary Medical School. J Vet Med Educ. 2002;29(4):227–30.
Article
PubMed
Google Scholar
WSAVA. List of essential medicines for cats and dogs. 2020.
Anon. Medicines and Brexit. Vet Rec. 2016;179(10):238.
Article
Google Scholar
Europeam Medicines Agency. Availability of medicines: Europeam Medicines Agency; 2020 [Available from: https://www.ema.europa.eu/en/human-regulatory/post-authorisation/availability-medicines.
Tan YX, Moles RJ, Chaar BB. Medicine shortages in Australia: causes, impact and management strategies in the community setting. Int J Clin Pharm. 2016;38(5):1133–41.
Article
PubMed
Google Scholar
Beck M, Buckley J, O’Reilly S. Managing pharmaceutical shortages: an overview and classification of policy responses in Europe and the USA. Int Rev Admin Sci. 2019;0(0):0020852318815330.
Google Scholar
Charan J, Kantharia ND. How to calculate sample size in animal studies? J Pharmacol Pharmacother. 2013;4(4):303–6.
Article
PubMed
PubMed Central
Google Scholar
Cai J, Zeng D. Sample size/power calculation for case–cohort studies. Biometrics. 2004;60(4):1015–24.
Article
PubMed
Google Scholar
Fosgate GT. Practical sample size calculations for surveillance and diagnostic investigations. J Vet Diagn Invest. 2009;21(1):3–14.
Article
PubMed
Google Scholar
Dohoo I, Martin W, Stryhn H. Veterinary epidemiologic research. 2nd ed. Charlottetown: VER Inc; 2009.
Google Scholar
Thrusfield M. Veterinary epidemiology. 3rd ed. Oxford: Blackwell Publishing; 2007. p. 610.
Google Scholar
Skelly AC, Dettori JR, Brodt ED. Assessing bias: the importance of considering confounding. Evid Based Spine-Care J. 2012;3(1):9–12.
Article
PubMed
PubMed Central
Google Scholar
Hernán M, Robins J. Causal inference. Boca Raton: Chapman & Hall/CRC; 2018.
Google Scholar
Kumar S, Hussain K, Sharma R, Chhibber S, Sharma N. Prevalence of canine otitis externa in Jammu. J Anim Res. 2014;4(1):121.
Article
CAS
Google Scholar
Boyd C, Jarvis S, McGreevy PD, Heath S, Church DB, Brodbelt DC, et al. Mortality resulting from undesirable behaviours in dogs aged under three years attending primary-care veterinary practices in England. Anim Welfare. 2018;27(3):251–62.
Article
Google Scholar
Erlen A, Potschka H, Volk HA, Sauter-Louis C, O’Neill DG. Seizure occurrence in dogs under primary veterinary care in the UK: prevalence and risk factors. J Vet Intern Med. 2018;32(5):1665–76.
Article
PubMed
PubMed Central
Google Scholar
Dorn CR. Survey of animal neoplasms in Alameda and Contra Costa Counties, California II. Cancer morbidity in dogs and cats from Alameda County. J Natl Cancer Inst. 1968;40:307–18.
CAS
PubMed
Google Scholar
Bush BM. The incidence of significant bacteriuria in the dog. Tijdschr Diergeneeskd. 1978;103(14):750–7.
CAS
PubMed
Google Scholar
Taylor-Brown FE, Meeson RL, Brodbelt DC, Church DB, McGreevy PD, Thomson PC, et al. Epidemiology of cranial cruciate ligament disease diagnosis in dogs attending primary-care veterinary practices in England. Vet Surg. 2015;44(6):777–83.
Article
PubMed
Google Scholar
O’Neill DG, Riddell A, Church DB, Owen L, Brodbelt DC, Hall JL. Urinary incontinence in bitches under primary veterinary care in England: prevalence and risk factors. J Small Anim Pract. 2017;58(12):685–93.
Article
PubMed
Google Scholar
German AJ. The growing problem of obesity in dogs and cats. J Nutr. 2006;136(7):1940S-6S.
Article
Google Scholar
Anderson KL, O’Neill DG, Brodbelt DC, Church DB, Meeson RL, Sargan D, et al. Prevalence, duration and risk factors for appendicular osteoarthritis in a UK dog population under primary veterinary care. Sci Rep. 2018;8(1):5641.
Article
PubMed
PubMed Central
CAS
Google Scholar
Pegram C, Brodbelt DC, Church DB, Hall J, Owen L, Chang Y-M, et al. Associations between neutering and early-onset urinary incontinence in UK bitches under primary veterinary care. J Small Anim Pract. 2019;60:723–33.
Article
CAS
PubMed
PubMed Central
Google Scholar
Pearl J. Interpretation and identification of causal mediation. Psychol Methods. 2014;19(4):459.
Article
PubMed
Google Scholar
Greenland S, Pearl J, Robins JM. Causal diagrams for epidemiologic research. Epidemiology. 1999;10(1):37–48.
Article
CAS
PubMed
Google Scholar
Abdi H. Bonferroni and Šidák corrections for multiple comparisons. In: Salkind NJ, editor. Encyclopedia of measurement and statistics. 3rd ed. Thousand Oaks; London: Sage; 2007. p. 103–7.
Google Scholar
Ludbrook J. Multiple comparison procedures updated. Clin Exp Pharmacol Physiol. 1998;25(12):1032–7.
Article
CAS
PubMed
Google Scholar
Bender R, Lange S. Adjusting for multiple testing - when and how? J Clin Epidemiol. 2001;54(4):343–9.
Article
CAS
PubMed
Google Scholar
Streiner DL, Norman GR. Correction for multiple testing: is there a resolution? Chest. 2011;140(1):16–8.
Article
PubMed
Google Scholar
O’Neill DG, Pegram C, Crocker P, Brodbelt DC, Church DB, Packer RMA. Unravelling the health status of brachycephalic dogs in the UK using multivariable analysis. Sci Rep. 2020;10(1):17251.
Article
PubMed
PubMed Central
CAS
Google Scholar
VetCompass. VetCompass programme London: RVC Electronic Media Unit; 2020 [Available from: http://www.rvc.ac.uk/VetCOMPASS/.
The VeNom Coding Group. VeNom veterinary nomenclature: VeNom Coding Group; 2020 [Available from: http://venomcoding.org.
Pearce N. Classification of epidemiological study designs. Int J Epidemiol. 2012;41(2):393–7.
Article
PubMed
Google Scholar
Epi Info 7 CDC. Centers for disease control and prevention (US): introducing Epi Info 7 Atlanta: CDC; 2019 [Available from: http://wwwn.cdc.gov/epiinfo/7.
O’Neill DG, Church DB, McGreevy PD, Thomson PC, Brodbelt DC. Prevalence of disorders recorded in dogs attending primary-care veterinary practices in England. PloS one. 2014c;9(3):e90501.
Article
PubMed Central
Google Scholar
Kirkwood BR, Sterne JAC. Essential medical statistics. 2nd ed. Oxford: Blackwell Science; 2003.
Google Scholar
Burnham KP, Anderson DR. Model selection and multi-model inference: a practical information-theoretic approach. 2nd ed. New York: Springer; 2002.
Google Scholar