Nielsen TO, Hsu FD, Jensen K, et al. Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma. Clin Cancer Res. 2004;10(16):5367–74.
Article
CAS
PubMed
Google Scholar
Rakha EA, Reis-Filho JS, Baehner F, et al. Breast cancer prognostic classification in the molecular era: the role of histological grade. Breast Cancer Res. 2010;12(4):207.
Article
PubMed
PubMed Central
Google Scholar
Weigelt B, Reis-Filho JS. Molecular profiling currently offers no more than tumour morphology and basic immunohistochemistry. Breast Cancer Res. 2010;12(Suppl 4):S5.
Article
PubMed
PubMed Central
Google Scholar
Tang P, Skinner KA, Hicks DG. Molecular classification of breast carcinomas by immunohistochemical analysis: are we ready? Diagn Mol Pathol. 2009;18(3):125–32.
Article
CAS
PubMed
Google Scholar
Zappulli L, Peña L, Rasotto R, Goldschmidt MH, Gama A, Scruggs JL, Kiupel M. Volume 2: Mamamary Tumour. In: Kiupel M, editor. Surgical Pathology of Tumors of Domestic Animals. Washington, DC: Davis-Thompson DVM Foundation; 2019. p. 1–195.
Google Scholar
Gama A, Alves A, Schmitt F. Identification of molecular phenotypes in canine mammary carcinomas with clinical implications: application of the human classification. Virchows Arch. 2008;453(2):123–32.
Article
CAS
PubMed
Google Scholar
Sassi F, Benazzi C, Castellani G, Sarli G. Molecular-based tumour subtypes of canine mammary carcinomas assessed by immunohistochemistry. BMC Vet Res. 2010;6:5.
Article
PubMed
PubMed Central
Google Scholar
Im KS, Kim NH, Lim HY, Kim HW, Shin JI, Sur JH. Analysis of a new histological and molecular-based classification of canine mammary neoplasia. Vet Pathol. 2014;51(3):549–59.
Article
CAS
PubMed
Google Scholar
Abadie J, Nguyen F, Loussouarn D, et al. Canine invasive mammary carcinomas as models of human breast cancer. Part 2: immunophenotypes and prognostic significance. Breast Cancer Res Treat. 2018;167(2):459–68.
Article
CAS
PubMed
Google Scholar
Mills M, Yang GQ, Oliver DE, et al. Histologic heteroneneity of triple negative breast cancer: A National Cancer Centre Database analysis. Eur J Cancer. 2018;98:48–58.
Article
PubMed
Google Scholar
Kim NH, Lim HY, Im KS, Kim JH, Sur JH. Identification of triple-negative and basal-like canine mammary carcinomas using four basal markers. J Comp Pathol. 2013;148(4):298–306.
Article
CAS
PubMed
Google Scholar
Lin NU, Vanderplas A, Hughes ME, et al. Clinicopathologic features, patterns of recurrence, and survival among women with triple-negative breast cancer in the National Comprehensive Cancer Network. Cancer. 2012;118(22):5463–72.
Article
PubMed
Google Scholar
Engebraaten O, Vollan HKM, Borrensen-Dale AL. Triple-negative breast cáncer and the need for new therapeutic targets. Am J Pathol. 2013;183(4):1064–74.
Article
CAS
PubMed
Google Scholar
Schmadeka MD, Harmon BE, Singh M. Triple-negative breast carcinoma. Am J Clin Pathol. 2014;141(4):462–77.
Article
CAS
PubMed
Google Scholar
Jaillardon L, Abadie J, Godard T, et al. The dog as a naturally-occurring model for insulin-like growth factor type 1 receptor-overexpressing breast cancer: an observational cohort study. BMC Cancer. 2015;15:664.
Article
PubMed
PubMed Central
CAS
Google Scholar
Kim HW, Lim HY, Shin JI, Seung BJ, Ju JH, Sur JH. Breed- and age-related differences in canine mammary tumors. Can J Vet Res. 2016;80(2):146–55.
PubMed
PubMed Central
Google Scholar
Dimitrov V, Salehi-Tabar R, An BS, White JH. Non-classical mechanisms of transcriptional regulation by the vitamin D receptor: insights into calcium homeostasis, immune system regulation and cancer chemoprevention. J Steroid Biochem Mol Biol. 2014;144(Pt):74–80.
Article
CAS
PubMed
Google Scholar
Khammissa RAG, Fourie J, Motswaledi MH, Ballyram R, Lemmer J, Feller L. The Biological Activities of Vitamin D and Its Receptor in Relation to Calcium and Bone Homeostasis, Cancer, Immune and Cardiovascular Systems, Skin Biology, and Oral Health. Biomed Res Int. 2018;2018:9276380.e
Article
CAS
PubMed
PubMed Central
Google Scholar
Deeb KK, Trump DL, Johnson CS. Vitamin D signalling pathways in cancer: potential for anticancer therapeutics. Nat Rev Cancer. 2007;7(9):684–700.
Article
CAS
PubMed
Google Scholar
Bandera Merchan B, Morcillo S, Martin-Nuñez G, Tinahones FJ, Macías-González M. The role of vitamin D and VDR in carcinogenesis: Through epidemiology and basic sciences. J Steroid Biochem Mol Biol. 2017;167:203–18.
Article
CAS
PubMed
Google Scholar
Duffy MJ, Murray A, Synnott NC, O´Donovan N, Crown J. Vitamin D analogues: Potential use in cancer treatment. Crit Rev Oncol Hematol. 2017;112:190–7.
Article
PubMed
Google Scholar
Gombart AF, Luong QT, Koeffler HP. Vitamin D compounds: activity against microbes and cancer. Anticancer Res. 2006;26(4A):2531–42.
CAS
PubMed
Google Scholar
Russell DS, Rassnick KM, Erb HN, Vaughan MM, McDonough SP. An immunohistochemical study of Vitamin D receptor expression in canine cutaneous mast cell tumours. J Comp Pathol. 2010;143(2–3):223–6.
Article
CAS
PubMed
Google Scholar
Catwright JA, Gow AG, Milne E, et al. Vitamin D receptor expression in dogs. J Vet Intern Med. 2018;32(2):764–74.
Article
Google Scholar
Davies J, Heeb H, Garimella R, Templeton K, Pinson D, Tawfik O. Vitamin d receptor, retinoid x receptor, ki-67, survivin, and ezrin expression in canine osteosarcoma. Vet Med Int. 2012;2:761034.
Welsh J. Function of the vitamin D endocrine system in mammary gland and breast cancer. Mol Cell Endocrinol. 2017;453:88–95.
Article
CAS
PubMed
PubMed Central
Google Scholar
Al-Azhri J, Zhang Y, Bshara W, et al. Tumour expression of vitamin D receptor and breast cancer histopathological characteristics and prognosis. Clin Cancer Res. 2017;23(1):97–103.
Article
CAS
PubMed
Google Scholar
Huss L, Butt ST, Borgquist S, et al. Vitamin D receptor expression in invasive breast tumors and breast cancer survival. Breast Cancer Res. 2019;21(1):84.
Article
PubMed
PubMed Central
CAS
Google Scholar
Francis I, AlAbdali N, Kapila K, John B, Al-Temaimi RA. Vitamin D pathway related polymorphisms and vitamin D receptor expression in breast cancer. Int J Vitam Nutr Res. 2021;91(1–2):124–32.
Article
PubMed
Google Scholar
Sánchez-Céspedes R, Fernández-Martínez MD, Raya A, Pineda C, López I, Millán Y. Vitamin D receptor expression in canine mammary gland and relationship with clinicopathological parameters and progesterone/oestrogen receptors. Vet Comp Oncol. 2018;16(1):E185–93.
Thakkar A, Wang B, Picon-Ruiz M, Buchwald P, Ince TA. Vitamin D and androgen receptor-targeted therapy for triple-negative breast cancer. Breast Cancer Res Treat. 2016;157(1):77–90.
Article
CAS
PubMed
PubMed Central
Google Scholar
Soljic M, Mrklic I, Tomic S, et al. Prognostic value of vitamin D receptor and insulin-like growth factor receptor 1 expression in triple-negative breast cancer. J Clin Pathol. 2018;71(1):34–9.
Article
CAS
PubMed
Google Scholar
Ranieri G, Gadaleta CD, Patruno R, et al. A model of study for human cancer: spontaneous occurring tumors in dogs. Biological features and translation for new anticancer therapies. Crit Rev Oncol Hematol. 2013;88(1):187–97.
Article
CAS
PubMed
Google Scholar
Nguyen F, Peña L, Ibisch C, et al. Canine invasive mammary carcinomas as models of human breast cancer. Part 1: natural history and prognostic factors. Breast Cancer Res Treat. 2018;167(3):635–48.
Article
CAS
PubMed
Google Scholar
Abdelmegeed SM, Mohammed S. Canine mammary tumors as a model for human disease. Oncol Lett. 2018;15(6):8195–205.
PubMed
PubMed Central
Google Scholar
Zhang H, Pei S, Zhou B, et al. Establishment and characterization of a new triple-negative canine mammary cancer cell line. Tissue Cell. 2018;54:10–9.
Article
CAS
PubMed
Google Scholar
Gray M, Meehan J, Martínez-Pérez C, et al. Naturally-Occurring Canine Mammary Tumors as a Translational Model for Human Breast Cancer. Front Oncol. 2020;10:617.
Article
PubMed
PubMed Central
Google Scholar
Perou CM, Sorlie T, Eisen MB, et al. Molecular portraits of human breast tumours. Nature. 2000;406:747–52.
Article
CAS
PubMed
Google Scholar
Engstrom MJ, Valla M, Bofin AM. Basal markers and prognosis in luminal breast cancer. Breast Cancer Res Treat. 2017;163(2):207–17.
Article
PubMed
CAS
Google Scholar
Rasotto R, Goldschmidt MH, Castagnaro M, Carnier P, Calirai D, Zappulli V. The dog as a natural animal model for study of the mammary myoepithelial basal cell lineage and its role in mammary carcinogenesis. J Comp Pathol. 2014;151(2–3):166–80.
Article
CAS
PubMed
Google Scholar
Sánchez-Céspedes R, Maniscalco L, Iussich S, et al. Isolation, purification, culture and characterization of myoepithelial cells from normal and neoplastic canine mammary glands using a magnetic-activated cell sorting separation system. Vet J. 2013;197(2):474–82.
Article
PubMed
CAS
Google Scholar
Sánchez-Céspedes R, Millán Y, Guil-Luna S, Reymundo C. Espinosa de Los Monteros A, Martín de Las Mulas J. Myoepithelial cells in canine mammary tumours. Vet J. 2016;207:45–52.
Article
PubMed
CAS
Google Scholar
Sánchez-Céspedes R, Millán Y, Guil-Luna S, et al. Immunohistochemical and quantitative RT-PCR methods to assess RANK expression in normal and neoplastic canine mammary gland. J Vet Diagn Invest. 2018;30(1):155–60.
Article
PubMed
CAS
Google Scholar
Guil-Luna S, Sánchez-Céspedes R, Millán Y, et al. Aglepristone decreases proliferation in progesterone receptor-positive canine mammary carcinomas. J Vet Intern Med. 2011;25(3):518–23.
Article
CAS
PubMed
Google Scholar
Martín de las Mulas J, Millán Y, Dios R. A prospective analysis of immunohistochemically determined estrogen receptor alpha and progesterone receptor expression and host and tumor factors as predictors of disease-free period in mammary tumors of the dog. Vet Pathol. 2005;42(2):200–12.
Article
PubMed
Google Scholar
Murray A, Madden SF, Synnott NC, et al. Vitamin D receptor as a target for breast cancer therapy. Endocr Relat Cancer. 2017;24(4):181–95.
Article
CAS
PubMed
Google Scholar
Jones G. Vitamin D analogs. Endocrinol Metab Clin North Am. 2010;39(2):447–72.
Article
CAS
PubMed
Google Scholar
Mehta RG, Peng X, Alimirah F, Murillo G, Mehta R. Vitamin D and breast cancer: emerging concepts. Cancer Lett. 2013;334(1):95–100.
Article
CAS
PubMed
Google Scholar
Fan C, Oh DS, Wessels L, et al. Concordance among gene-expression-based predictors for breast cancer. N Engl J Med. 2006;235(6):560–9.
Article
Google Scholar
Goldschmidt M, Peña L, Rasotto R, Zappulli V. Classification and grading of canine mammary tumours. Vet Pathol. 2011;48(1):117–31.
Article
CAS
PubMed
Google Scholar
Chang CC, Tsai MH, Liao JW, Chan JP, Wong ML, Chang SC. Evaluation of hormone receptor expression for use in predicting survival of female dogs with malignant mammary gland tumours. J Am Vet Med Assoc. 2009;235(4):391–6.
Article
CAS
PubMed
Google Scholar
Iwase H, Zhang Z, Omoto Y, et al. Clinical significance of the expression of estrogen receptors alpha and beta for endocrine therapy of breast cancer. Cancer Chemother Pharmacol. 2003;52(Suppl 1):S34–8.
Cheang MC, Chia SK, Voduc D, et al. Ki67 index, HER2 status, and prognosis of patients with luminal B breast cancer. J Nat Cancer Inst. 2009;101(10):736–50.
Article
CAS
PubMed
PubMed Central
Google Scholar
Karayannopoulou M, Kaldrymidou E, Constantinidis TC, et al. Histological grading and prognosis in dogs with mammary carcinomas: application of a human grading method. J Comp Pathol. 2005;133(4):246–52.
Article
CAS
PubMed
Google Scholar
Pandey PR, Saidou J, Watabe K. Role of myoepithelial cells in breast tumor progression. Front Biosci. 2010;15:226–36.
Article
CAS
PubMed Central
Google Scholar
Shamloula MM, El-Shorbagy SH, Saied EM. P63 and cytokeratin8/18 expression in breast, atypical ductal hyperplasia, ductal carcinoma in situ and invasive duct carcinoma. J Egypt Natl Canc Inst. 2007;202–2010
Mardekian SK, Bombonati A, Palazzo JP. Ductal carcinoma in situ of the breast: the importance of morphologic and molecular interactions. Human Pathol. 2010;49:114–23.
Article
CAS
Google Scholar
Lopuszynski W, Szczubial M, Millán Y, et al. Immunohistochemical expresion of p63 protein and calponin in canine mammary tumours. Res Vet Sci. 2019;123:232–8.
Article
CAS
PubMed
Google Scholar
Peña L, De Andrés PJ, Clemente M, Cuesta P, Pérez-Alenza MD. Prognostic value of histological grading in noninflamatory canine mammary carcinomas in a prospective study with two-year follow-up: relationship with clinical and histological characteristics. Vet Pathol. 2013;50(1):94–105.
Article
PubMed
Google Scholar
Burrai GP, Tanca A, De Miglio MR, et al. Investigation of HER2 expression in canine mammary tumors by antibody-based, transcriptomic and mass spectrometry analysis: is the dog a suitable animal model for human breast cancer? Tumour Biol. 2015;36(11):9083–91.
Article
CAS
PubMed
Google Scholar
Campos LC, Silva JO, Santos FS, et al. Prognostic significance of tissue and serum HER2 and MUC1 in canine mammary cancer. J Vet Diagn Invest. 2015;27(4):531–5.
Article
CAS
PubMed
Google Scholar
Ramalho LN, Ribeiro-Silva A, Cassali GD, Zucoloto S. The expression of p63 and cytokeratin 5 in mixed tumors of the canine mammary gland provides new insights into the histogenesis of these neoplasms. Vet Pathol. 2006;43(4):424–9.
Article
CAS
PubMed
Google Scholar
Lai CL, van den Ham R, van Leenders G, van der Lugt J, Mol JA, Teske E. Histopathological and immunohistochemical characterization of canine prostate cancer. Prostate. 2008;68(5):477–88.
Article
PubMed
Google Scholar
Kishimoto TE, Yoshimura H, Saito N, et al. Salivary gland epitelial-myoepithelial carcinoma with high-grade transformation in a dog. J Comp Pathol. 2015;153:111–5.
Article
CAS
PubMed
Google Scholar
Lopes N, Sousa B, Martins D, et al. Alterations in Vitamin D signalling and metabolic pathways in breast cancer progression: a study of VDR, CYP27B1 and CYP24A1 expression in benign and malignant breast lesions. BMC Cancer. 2010;10:483.
Article
PubMed
PubMed Central
CAS
Google Scholar
Wolff AC, Hammond MEH, Allison KH, et al. Human epidermal growth factor receptor 2 testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline Focused Update. J Clin Oncol. 2018;36(20):2105–22.
Article
CAS
PubMed
Google Scholar
Allred DC, Harvey JM, Berardo M, Clark GM. Prognostic and predictive factors in breast cancer by immunohistochemical analysis. Mod Pathol. 1998;11(2):155–68.
CAS
PubMed
Google Scholar