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  1. During last decade Lampedusa island (Italy) has been interested by a deep social change caused by the massive arrival of migrants from north Africa. The goal of this study was to evaluate current CanL burden a...

    Authors: Valentina Foglia Manzillo, Manuela Gizzarelli, Fabrizio Vitale, Serena Montagnaro, Alessandra Torina, Salvo Sotera and Gaetano Oliva
    Citation: BMC Veterinary Research 2018 14:286
    Content type: Research article Published on:

  2. Rabies is a major zoonotic disease affecting humans, domestic and wildlife mammals. Cattle are the most important domestic animals impacted by rabies virus in the New World, leading to thousands of cattle deat...

    Authors: Sabine E. Hutter, Annemarie Käsbohrer, Silvia Lucia Fallas González, Bernal León, Katharina Brugger, Mario Baldi, L. Mario Romero, Yan Gao and Luis Fernando Chaves
    Citation: BMC Veterinary Research 2018 14:285
    Content type: Research article Published on:

  3. Infectious bronchitis (IB) caused by the IB virus (IBV) can cause acute damage to chickens around the world. Therefore, rapid diagnosis and immune status determination are critical for controlling IBV outbreak...

    Authors: Liping Yan, Jianhua Hu, Jing Lei, Zhiyu Shi, Qian Xiao, Zhenwei Bi, Lu Yao, Yuan Li, Yuqing Chen, An Fang, Hui Li, Suquan Song, Min Liao and Jiyong Zhou
    Citation: BMC Veterinary Research 2018 14:284
    Content type: Methodology article Published on:

  4. Adverse food reactions (AFRs) are defined as abnormal responses to an ingested food or food additive. Diagnosis and treatment of AFRs consist of the complete elimination of these ingredients in the dietary tri...

    Authors: Elena Pagani, Maria de los Dolores Soto del Rio, Alessandra Dalmasso, Maria Teresa Bottero, Achille Schiavone and Liviana Prola
    Citation: BMC Veterinary Research 2018 14:283
    Content type: Research article Published on:

  5. Propofol is one of the most widely used injectable anaesthetic agents in veterinary practice. Cardiovascular effects related to propofol use in dogs remain less well defined. The main objective of this study w...

    Authors: Andrea Cattai, Roberto Rabozzi, Heidi Ferasin, Maurizio Isola and Paolo Franci
    Citation: BMC Veterinary Research 2018 14:282
    Content type: Research article Published on:

  6. Incubation period, disease progression, pathology and clinical presentation of classical scrapie in sheep are highly dependent on PRNP genotype, time and route of inoculation and prion strain. Our experimental mo...

    Authors: Siv Meling, Kerstin Skovgaard, Kjetil Bårdsen, Peter Mikael Helweg Heegaard and Martha J. Ulvund
    Citation: BMC Veterinary Research 2018 14:281
    Content type: Research article Published on:

  7. Newcastle disease virus, in its most pathogenic form, threatens the livelihood of rural poultry farmers where there is a limited infrastructure and service for vaccinations to prevent outbreaks of the virus. P...

    Authors: Perot Saelao, Ying Wang, Rodrigo A. Gallardo, Susan J. Lamont, Jack M. Dekkers, Terra Kelly and Huaijun Zhou
    Citation: BMC Veterinary Research 2018 14:280
    Content type: Research article Published on:

  8. The role of bats as reservoirs of zoonotic agents, especially pathogenic bacteria such as Bartonella and Coxiella, has been discussed around the world. Recent studies have identified bats as potential hosts of...

    Authors: Michelle Santos Ferreira, Alexandro Guterres, Tatiana Rozental, Roberto Leonan Morim Novaes, Emmanuel Messias Vilar, Renata Carvalho de Oliveira, Jorlan Fernandes, Danielle Forneas, Adonai Alvino Junior, Martha Lima Brandão, José Luis Passos Cordeiro, Martín Roberto Del Valle Alvarez, Sergio Luiz Althoff, Ricardo Moratelli, Pedro Cordeiro-Estrela, Rui Cerqueira da Silva…
    Citation: BMC Veterinary Research 2018 14:279
    Content type: Research article Published on:

  10. Simbu serogroup viruses of the Orthobunyavirus genus (Family Peribunyaviridae) include teratogenic pathogens that cause severe economic losses, abortions, stillbirths and congenital abnormalities in ruminants wor...

    Authors: Daniel Oluwayelu, Kerstin Wernike, Adebowale Adebiyi, Simeon Cadmus and Martin Beer
    Citation: BMC Veterinary Research 2018 14:277
    Content type: Research article Published on:

  12. Currently, little is known about the effect of sodium butyrate (NaB) on oxidative stress following grain-induced sub-acute ruminal acidosis in dairy goats. In the present study, 18 lactating dairy goats implan...

    Authors: Nana Ma, Juma Ahamed Abaker, Muhammad Shahid Bilal, Hongyu Dai and Xiangzhen Shen
    Citation: BMC Veterinary Research 2018 14:275
    Content type: Research article Published on:

  13. Rabies is the only known zoonotic disease of bat origin in Europe. The disease is caused by species belonging to the genus Lyssavirus. Five Lyssavirus species, i.e., European bat lyssavirus (EBLV)-1, EBLV-2, Boke...

    Authors: Ivana Šimić, Ivana Lojkić, Nina Krešić, Florence Cliquet, Evelyne Picard-Meyer, Marine Wasniewski, Anđela Ćukušić, Vida Zrnčić and Tomislav Bedeković
    Citation: BMC Veterinary Research 2018 14:274
    Content type: Research article Published on:

  14. Bovine tuberculosis (bTB) is a zoonotic disease of cattle caused by Mycobacterium bovis, widespread in England and Wales. It has high incidence towards the South West of England and Wales, with much lower inciden...

    Authors: Colin P. D. Birch, Ashley Goddard and Oliver Tearne
    Citation: BMC Veterinary Research 2018 14:273
    Content type: Research article Published on:

  15. Effective treatment options for inoperable, metastatic, or recurrent canine pheochromocytomas are lacking. In humans, specific germline mutations exist that drive the development of pheochromocytomas. Pharmace...

    Authors: Margaret L. Musser, Kathryn L. Taikowski, Chad M. Johannes and Philip J. Bergman
    Citation: BMC Veterinary Research 2018 14:272
    Content type: Research article Published on:

  16. Rift Valley fever (RVF) is classified as viral hemorrhagic fever and is endemic in East and West Africa. RVF is caused by an arthropod borne virus (RVFV); the disease is zoonotic and affects human, animal heal...

    Authors: Ngabo Herbert Budasha, Jean-Paul Gonzalez, Tesfaalem Tekleghiorghis Sebhatu and Ezama Arnold
    Citation: BMC Veterinary Research 2018 14:271
    Content type: Research article Published on:

  17. The presence of cranial tibial subluxation can aid in the detection of joint instability as a result of CrCL injury. Detection of cranial tibial subluxation has been described using the tibial compression test...

    Authors: Katrina A. Castaneda, Caleb C. Hudson and Brian S. Beale
    Citation: BMC Veterinary Research 2018 14:270
    Content type: Methodology article Published on:

  18. The fluorescein clearance test (FCT) provides insight into the tear film dynamics. The purpose of this study was to describe an inexpensive and practical method for assessing FCT in dogs, using photography and...

    Authors: Arianne Pontes Oriá, Miriam Flores Rebouças, Emanoel Martins Filho, Francisco de Assis Dórea Neto, Ana Cláudia Raposo and Lionel Sebbag
    Citation: BMC Veterinary Research 2018 14:269
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Veterinary Research 2018 14:305

  19. African swine fever virus (ASFV) is the etiological agent of African swine fever (ASF), a re-expanding devastating and highly lethal hemorrhagic viral disease. microRNAs (miRNAs) are a new class of small non-c...

    Authors: Fernando Núñez-Hernández, Gonzalo Vera, Armand Sánchez, Fernando Rodríguez and José I. Núñez
    Citation: BMC Veterinary Research 2018 14:268
    Content type: Research article Published on:

  20. Muscovy duck parvovirus (MDPV) causes high mortality and morbidity in Muscovy ducks, with the pathogenesis of the virus still unknown in many respects. Specific MDPV detection is often rife with false positive...

    Authors: Chunhe Wan, Cuiteng Chen, Longfei Cheng, Hongmei Chen, Qiuling Fu, Shaohua Shi, Guanghua Fu, Rongchang Liu and Yu Huang
    Citation: BMC Veterinary Research 2018 14:267
    Content type: Research article Published on:

  21. Sarcoids are the mostcommon skin tumors in horses, characterized by rare regression, invasiveness and high recurrence following surgical intervention and Delta Papillomaviruses are widely recognized as the cau...

    Authors: Manuela Martano, Karen Power, Brunella Restucci, Ilaria Pagano, Gennaro Altamura, Giuseppe Borzacchiello and Paola Maiolino
    Citation: BMC Veterinary Research 2018 14:266
    Content type: Research article Published on:

  22. Timely diagnosis of influenza A virus infections is critical for outbreak control. Due to their rapidity and other logistical advantages, lateral flow immunoassays can support influenza A virus surveillance pr...

    Authors: Amos Ssematimba, Sasidhar Malladi, Peter J. Bonney, Cristian Flores-Figueroa, Jeannette Muñoz-Aguayo, David A. Halvorson and Carol J. Cardona
    Citation: BMC Veterinary Research 2018 14:265
    Content type: Research article Published on:

  23. Recently, mammalian orthoreoviruses (MRVs) were detected for the first time in European bats, and the closely related strain SI-MRV01 was isolated from a child with severe diarrhoea in Slovenia. Genetically si...

    Authors: Tina Naglič, Danijela Rihtarič, Peter Hostnik, Nataša Toplak, Simon Koren, Urška Kuhar, Urška Jamnikar-Ciglenečki, Denis Kutnjak and Andrej Steyer
    Citation: BMC Veterinary Research 2018 14:264
    Content type: Research article Published on:

  24. Foot-and-mouth disease (FMD), which is caused by foot-and-mouth disease virus (FMDV), is a highly contagious tansboundary disease of cloven-hoofed animals and causes devastating economic damages. Accurate, rap...

    Authors: Libing Liu, Jinfeng Wang, Ruoxi Zhang, Mi Lin, Ruihan Shi, Qingan Han, Jianchang Wang and Wanzhe Yuan
    Citation: BMC Veterinary Research 2018 14:263
    Content type: Methodology article Published on:

  25. Treatment of infected otitis externa (OE) relies on the topical application of specific formulations that most often contain an antibiotic, an antifungal and a glucocorticoid. This study is to report the resul...

    Authors: S. L. Forster, T. Real, K. P. Doucette and S. B. King
    Citation: BMC Veterinary Research 2018 14:262
    Content type: Research article Published on:

  26. Commensal bacterial and fungal flora of the conjunctival sac has been described in horses and other animals. The identification of commensal flora of the conjunctival sac may aid in the diagnosis of ocular inf...

    Authors: A. Zak, N. Siwinska, M. Slowikowska, H. Borowicz, K. Ploneczka – Janeczko, P. Chorbinski and A. Niedzwiedz
    Citation: BMC Veterinary Research 2018 14:261
    Content type: Research article Published on:

  27. The generation of recombinant proteins for commercialisation must be cost-effective. Despite the cost-effective production of recombinant feline interferon (rFeIFN) by a baculovirus expression system, this rFe...

    Authors: Sachi Minagawa, Yuzuru Nakaso, Masahiro Tomita, Takenori Igarashi, Yoshio Miura, Hideyo Yasuda and Satoshi Sekiguchi
    Citation: BMC Veterinary Research 2018 14:260
    Content type: Research article Published on:

  28. Mechanical interactions between hard floorings and the sole of bovine claws can be reasonable to cause traumatic claw lesions. In this ex vivo study, the direct kinetic impact of concrete and three types of ru...

    Authors: Benjamin Oehme, S. M. Geiger, S. Grund, K. Hainke, J. Munzel and C. K. W. Mülling
    Citation: BMC Veterinary Research 2018 14:259
    Content type: Research article Published on:

  29. Inexpensive and convenient diagnostic tests for use in clinical work and for the surveillance of infection with Mycoplasma bovis are in demand. The objective of this longitudinal field study was to gain knowledge...

    Authors: Mette Bisgaard Petersen, Nadeeka K. Wawegama, Matthew Denwood, Philip F. Markham, Glenn F. Browning and Liza Rosenbaum Nielsen
    Citation: BMC Veterinary Research 2018 14:258
    Content type: Research article Published on:

  30. Salmonella is a major zoonotic food-borne pathogen that persists on poultry farms, and animals undergo reinfection with endemic strains. The present study aimed to investigate the characteristics and disseminatio...

    Authors: Ke Shang, Bai Wei and Min Kang
    Citation: BMC Veterinary Research 2018 14:257
    Content type: Research article Published on:

  31. Salivary alpha-amylase (sAA) is considered a non-invasive biomarker of acute stress that can be evaluated by changes in activity and concentration, and also by changes in its isoforms, although this last way o...

    Authors: María Dolores Contreras-Aguilar, Damián Escribano, Silvia Martínez-Subiela, Silvia Martínez-Miró, Jose Joaquín Cerón and Fernando Tecles
    Citation: BMC Veterinary Research 2018 14:256
    Content type: Research article Published on:

  32. Duck Enteritis Virus (DEV), belonging to the α-herpesvirus subfamily, is a linear double-stranded DNA virus. Glycoprotein H and L (gH and gL), encoded by UL22 and UL1, are conserved in the family of herpesviru...

    Authors: Daishen Feng, Min Cui, Renyong Jia, Siyang Liu, Mingshu Wang, Dekang Zhu, Shun Chen, Mafeng Liu, Xinxin Zhao, Yin Wu, Qiao Yang, Zhongqiong Yin and Anchun Cheng
    Citation: BMC Veterinary Research 2018 14:255
    Content type: Research article Published on:

  33. A direct contact transmission challenge model was used to simulate natural foot-and-mouth disease virus (FMDV) spread from FMDV A24/Cruzeiro/BRA/55 infected ‘seeder’ steers to naïve or vaccinated steers previo...

    Authors: John G. Neilan, Christopher Schutta, José Barrera, Melia Pisano, Laszlo Zsak, Ethan Hartwig, Max V. Rasmussen, Barbara J. Kamicker, Damodar Ettyreddy, Douglas E. Brough, Bryan T. Butman and David A. Brake
    Citation: BMC Veterinary Research 2018 14:254
    Content type: Research article Published on:

  34. Foot-and-mouth disease (FMD) is an acute viral disease of cloven-hoofed animals with high economic impact. FMD remains endemic in Iran particularly in the livestock-dense province of Khorasan Razavi in northea...

    Authors: Kayhan Ilbeigi, Saied Bokaie, Sina Aghasharif, Ricardo J. Soares Magalhães and Mohamad Rashtibaf
    Citation: BMC Veterinary Research 2018 14:253
    Content type: Research article Published on:

  35. Ovine footrot is a highly contagious bacterial disease of sheep, costing the Australian sheep industry millions of dollars annually. Dichelobacter nodosus, the causative agent of footrot, is a gram-negative anaer...

    Authors: Nickala Best, Lucas Zanandrez, Jacek Gwozdz, Eckard Klien, Nicky Buller, Robert Suter, Grant Rawlin and Travis Beddoe
    Citation: BMC Veterinary Research 2018 14:252
    Content type: Methodology article Published on:

  36. Candida spp. is the vital pathogen involved in mycotic mastitis of cows. However the epidemiology and infection of Candida species in mycotic mastitis of cow in Ningxia province of China has not been explored. In...

    Authors: Jun Du, Xiaoyu Wang, Huixia Luo, Yujiong Wang, Xiaoming Liu and Xuezhang Zhou
    Citation: BMC Veterinary Research 2018 14:251
    Content type: Research article Published on:

  37. Chemotherapeutic options for the treatment of canine lymphoma have not changed in several decades necessitating the identification of new therapeutics to improve patient outcome. KPT-335 (verdinexor) is a nove...

    Authors: Abbey R. Sadowski, Heather L. Gardner, Antonella Borgatti, Heather Wilson, David M. Vail, Joshua Lachowicz, Christina Manley, Avenelle Turner, Mary K. Klein, Angharad Waite, Alexandra Sahora and Cheryl A. London
    Citation: BMC Veterinary Research 2018 14:250
    Content type: Research article Published on:

  38. Selenium (Se) and vitamin E (Vit E) can act synergistically and affect biological processes, mainly antioxidant and immunity. The use of excess dietary Vit E and Se in animals’ feed could enhance immune respon...

    Authors: A. M. Dalia, T. C. Loh, A. Q. Sazili, M. F. Jahromi and A. A. Samsudin
    Citation: BMC Veterinary Research 2018 14:249
    Content type: Research article Published on:

  39. In the last 20 years, Cetacean Morbillivirus (CeMV) has been responsible for many die-offs in marine mammals worldwide, as clearly exemplified by the three dolphin morbillivirus (DMV) epizootics of 1990–1992, ...

    Authors: Consuelo Rubio-Guerri, M. Ángeles Jiménez, Mar Melero, Josué Díaz-Delgado, Eva Sierra, Manuel Arbelo, Edwige N. Bellière, Jose L. Crespo-Picazo, Daniel García-Párraga, Fernando Esperón and Jose M. Sánchez-Vizcaíno
    Citation: BMC Veterinary Research 2018 14:248
    Content type: Research article Published on:

  40. Endothelial progenitor cells (EPCs) contribute to neovascularization and vascular repair in vivo and are attractive for clinical use in ischemic disease. Tracking of stem and progenitor cells is essential to d...

    Authors: Randolph L. Winter, Wen J. Seeto, Yuan Tian, Fred J. Caldwell, Elizabeth A. Lipke and Anne A. Wooldridge
    Citation: BMC Veterinary Research 2018 14:247
    Content type: Research article Published on:

  41. Staphylococcus aureus is a contagious, opportunistic pathogen that causes clinical or subclinical mastitis in dairy cattle. The genetic background and antimicrobial resistance of isolates from Ethiopian dairy far...

    Authors: S. A. Mekonnen, T. J. G. M. Lam, J. Hoekstra, V. P. M. G. Rutten, T. S. Tessema, E. M. Broens, A. E. Riesebos, M. P. Spaninks and G. Koop
    Citation: BMC Veterinary Research 2018 14:246
    Content type: Research article Published on:

  42. Equine herpesvirus type 1 (EHV-1) induces respiratory infection, abortion, and neurologic disease with significant impact. Virulence factors contributing to infection and immune evasion are of particular inter...

    Authors: Christiane L. Schnabel, Christine L. Wimer, Gillian Perkins, Susanna Babasyan, Heather Freer, Christina Watts, Alicia Rollins, Nikolaus Osterrieder and Bettina Wagner
    Citation: BMC Veterinary Research 2018 14:245
    Content type: Research article Published on:

  43. Pasteurella multocida type A (PmA) is considered a secondary agent of pneumonia in pigs. The role of PmA as a primary pathogen was investigated by challenging pigs with eight field strains isolated from pneumonia...

    Authors: João Xavier de Oliveira Filho, Marcos Antônio Zanella Morés, Raquel Rebellato, Jalusa Deon Kich, Maurício Egidio Cantão, Catia Silene Klein, Roberto Maurício Carvalho Guedes, Arlei Coldebella, David Emílio Santos Neves de Barcellos and Nelson Morés
    Citation: BMC Veterinary Research 2018 14:244
    Content type: Research article Published on:

  44. As the major causative agent of swine viral diarrhea, porcine epidemic diarrhea virus (PEDV) has caused massive losses to the economies of swine raising countries. Accordingly, the serological detection of cor...

    Authors: Huixing Lin, Hong Zhou, Lu Gao, Bin Li, Kongwang He and Hongjie Fan
    Citation: BMC Veterinary Research 2018 14:243
    Content type: Methodology article Published on:

  45. Robenacoxib is a non-steroidal anti-inflammatory drug available for canine and feline use for the control of pain and inflammation marketed as Onsior™. The aim of this target animal safety study was to evaluat...

    Authors: Céline E. Toutain, Patrick Brossard, Stephen B. King and Rainer Helbig
    Citation: BMC Veterinary Research 2018 14:242
    Content type: Research article Published on:

  46. This study aimed at assessing the effectiveness and safety of repeated administrations of allogeneic bone marrow-derived mesenchymal stem cells (BM-MSCs) primed with tumor necrosis factor (TNF)-α and interfero...

    Authors: Laura Barrachina, Ana Rosa Remacha, Antonio Romero, Arantza Vitoria, Jorge Albareda, Marta Prades, Mercedes Roca, Pilar Zaragoza, Francisco José Vázquez and Clementina Rodellar
    Citation: BMC Veterinary Research 2018 14:241
    Content type: Research article Published on:

  47. Porcine reproductive and respiratory syndrome (PRRS) is a severe disease, causing great economic losses to the pig industry. The causative agent, porcine reproductive and respiratory syndrome virus (PRRSV) is ...

    Authors: Weijie Bai, Zhijia Wang, Pu Sun, Jing Zhang, Huifang Bao, Yimei Cao, Yanyan Chang, Zaixin Liu, Dong Li and Zengjun Lu
    Citation: BMC Veterinary Research 2018 14:240
    Content type: Research article Published on:

  48. Peyer’s patches (PPs) can be considered as the immune site of the intestine. Within PPs, Dendritic cells (DCs) can uptake antigens from the gut lumen by extending dendrites into epithelium, and process it and ...

    Authors: Chen Yuan, En Zhang, Lulu Huang, Jialu Wang and Qian Yang
    Citation: BMC Veterinary Research 2018 14:239
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Veterinary Research 2018 14:303

  49. For decades, the efficacy of interventions in clinical trials enrolling dogs with atopic dermatitis (AD) relied on heterogeneous evaluations of skin lesions and pruritus using unvalidated tools. Although some ...

    Authors: Thierry Olivry, Emmanuel Bensignor, Claude Favrot, Craig E. Griffin, Peter B. Hill, Ralf S. Mueller, Jon D. Plant and Hywel C. Williams
    Citation: BMC Veterinary Research 2018 14:238
    Content type: Guidelines Published on:

  50. Apoptosis plays an important role in the regulation of healthy tissue growth and development as well as in controlling the maintenance of homeostasis in exercising muscles. During an intensive physical effort,...

    Authors: K. Ropka-Molik, M. Stefaniuk-Szmukier, K. Piórkowska, T. Szmatoła and M. Bugno-Poniewierska
    Citation: BMC Veterinary Research 2018 14:237
    Content type: Research article Published on:
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