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  1. Osteoarthritis (OA), the most common form of arthritic disease, results from destruction of joint cartilage and underlying bone. It affects animals, including Asian elephants (Elephas maximus) in captivity, leadi...

    Authors: Nutnicha Sirikaew, Siriwadee Chomdej, Siriwan Tangyuenyong, Weerapongse Tangjitjaroen, Chaleamchat Somgird, Chatchote Thitaram and Siriwan Ongchai
    Citation: BMC Veterinary Research 2019 15:419
    Content type: Research article Published on:

  2. Prostaglandin F2α (PGF2α) may differentially affect viability of luteal cells by inducing either proliferation or cell death (via apoptosis or necroptosis). The diverse effects of PGF2α may depend on its local vs...

    Authors: Agnieszka Walentyna Jonczyk, Katarzyna Karolina Piotrowska-Tomala and Dariusz Jan Skarzynski
    Citation: BMC Veterinary Research 2019 15:416
    Content type: Research article Published on:

  3. Currently, [18F] altanserin is the most frequently used PET-radioligand for serotonin2A (5-HT2A) receptor imaging in the human brain but has never been validated in dogs. In vivo imaging of this receptor in the c...

    Authors: Glenn Pauwelyn, Lise Vlerick, Robrecht Dockx, Jeroen Verhoeven, Andre Dobbeleir, Tim Bosmans, Kathelijne Peremans, Christian Vanhove, Ingeborgh Polis and Filip De Vos
    Citation: BMC Veterinary Research 2019 15:415
    Content type: Research article Published on:

  4. Fasciola hepatica is a liver parasite of mammals and it results in poor welfare outcomes and economic losses in ruminants. While faecal egg count is the test most commonly used for diagnosis, it does not indicate...

    Authors: Maria Pia Munita, Rosemary Rea, Ana Maria Martinez-Ibeas, Noel Byrne, Aideen Kennedy, Mary Sekiya, Grace Mulcahy and Riona Sayers
    Citation: BMC Veterinary Research 2019 15:414
    Content type: Research article Published on:

  5. Evolution of indolent to aggressive lymphoma has been described in dogs but is difficult to distinguish from the de novo development of a second, clonally distinct lymphoma. Differentiation of these scenarios ...

    Authors: Arata Matsuyama, Dorothee Bienzle, Danielle Richardson, Nariman Deravi, Mei-Hua Hwang, Nikos Darzentas and Stefan M. Keller
    Citation: BMC Veterinary Research 2019 15:413
    Content type: Case Report Published on:

  6. Canine leptospirosis is a reemerging zoonotic disease concern in North America, and a better understanding of its epidemiology is needed. Wide-scale use and subsequent analyses of polymerase chain reaction (PC...

    Authors: Amanda M. Smith, Andréia Gonçalves Arruda, Michelle D. Evason, J. S. Weese, Thomas E. Wittum, Donald Szlosek and Jason W. Stull
    Citation: BMC Veterinary Research 2019 15:412
    Content type: Research article Published on:

  7. Alopecia is defined as the partial or complete absence of hair from areas of the body where it normally grows. Alopecia secondary to an infectious disease or parasitic infestation is commonly seen in cattle. I...

    Authors: Matthias Wieland, Sabine Mann, Nicole S. Gollnick, Monir Majzoub-Altweck, Gabriela Knubben-Schweizer and Martin C. Langenmayer
    Citation: BMC Veterinary Research 2019 15:411
    Content type: Case Report Published on:

  8. Little information about the prevalence of gastrointestinal parasites in yaks (Bos grunniens) in northwest China is available. Therefore, the objective of the study was to quantify faecal egg counts of gastrointe...

    Authors: Si-Yuan Qin, Ming-Yang Yin, Guang-Yao Song, Qi-Dong Tan, Jin-Lei Wang and Dong-Hui Zhou
    Citation: BMC Veterinary Research 2019 15:410
    Content type: Research article Published on:

  9. Porcine epidemic diarrhea virus (PEDV) infection is a highly contagious infectious disease causing watery diarrhea, vomiting, dehydration and high mortality rate in newborn piglets. PEDV infection can cause hi...

    Authors: Ohnmar Myint, Ayako Yoshida, Satoshi Sekiguchi, Nguyen Van Diep, Naoyuki Fuke, Uda Zahli Izzati, Takuya Hirai and Ryoji Yamaguchi
    Citation: BMC Veterinary Research 2019 15:409
    Content type: Research article Published on:

  10. Akabane disease (AD), a barrier to international trade for endemic areas with far economic impact on the countries, is caused by Akabane virus (AKAV). Commercial enzyme-linked immunosorbent assay (ELISA) is a ...

    Authors: Xiaolin Li, Hongli Jing, Xiaofei Liu, Qin Wang, Songyin Qiu, Dandan Liu, Shaoqiang Wu and Xiangmei Lin
    Citation: BMC Veterinary Research 2019 15:408
    Content type: Methodology article Published on:

  11. Total skin electron beam radiation therapy (TSEBT) is an effective treatment for primary diffuse cutaneous lymphomas in humans. While several techniques exist, they all require significant commitment of staff ...

    Authors: Michael A. Deveau, Megan Sutton, Courtney Baetge and Alison B. Diesel
    Citation: BMC Veterinary Research 2019 15:407
    Content type: Case Report Published on:

  12. Enzootic bovine leukosis (EBL) is a disease of cattle caused by bovine leukemia virus (BLV). More than 60% of BLV-infected cattle remain subclinical and are thus referred to as aleukemic (AL) cattle. Approxima...

    Authors: Misako Konishi, Sota Kobayashi, Taeko Tokunaga, Yuzumi Chiba, Toshiyuki Tsutsui, Shozo Arai, Ken-ichiro Kameyama and Takehisa Yamamoto
    Citation: BMC Veterinary Research 2019 15:406
    Content type: Research article Published on:

  13. Canine leishmaniasis is a zoonotic disease caused by Leishmania infantum, being the dogs one of the major reservoirs of human visceral leishmaniasis. DNA topology is a consolidated target for drug discovery. In t...

    Authors: Rosa M. Reguera, Raquel Álvarez-Velilla, Bárbara Domínguez-Asenjo, Camino Gutiérrez-Corbo, Rafael Balaña-Fouce, Mark Cushman and Yolanda Pérez-Pertejo
    Citation: BMC Veterinary Research 2019 15:405
    Content type: Research article Published on:

  14. Many studies have revealed that bioactive compounds for different indications are not extracted from plants with water, the only extractant practically available to rural communities. We compared the acaricida...

    Authors: Emmanuel T. Nyahangare, Brighton M. Mvumi, Lyndy J. McGaw and Jacobus N. Eloff
    Citation: BMC Veterinary Research 2019 15:404
    Content type: Research article Published on:

  15. Leptospirosis is a neglected zoonosis of public health importance transmitted through contact with contaminated soil, water or urine of infected animals. In pigs the disease is characterized by abortion, still...

    Authors: Jeremiah N. Ngugi, Eric M. Fèvre, Georgies F. Mgode, Mark Obonyo, Ginethon G. Mhamphi, Christina A. Otieno and Elizabeth Anne Jessie Cook
    Citation: BMC Veterinary Research 2019 15:403
    Content type: Research article Published on:

  16. Designing a potent recombinant vaccine, using the appropriate subunits with the greatest effect on stimulating the immune system, especially in the case of intracellular pathogens such as gram negative Brucella M...

    Authors: Narges Nazifi, Mojtaba Tahmoorespur, Mohammad Hadi Sekhavati, Alireza Haghparast and Ali Mohammad Behroozikhah
    Citation: BMC Veterinary Research 2019 15:402
    Content type: Research article Published on:

  17. Dyslipidemias induce angiogenesis and accelerate the development and in vitro growth of breast tumors. The aim of this study was to assess the lipid and metabolic profile of female dogs with mammary carcinomas...

    Authors: Keidylania Costa-Santos, Karine Damasceno, Ricardo Dias Portela, Ferlando Lima Santos, Genira Carneiro Araújo, Emanoel Ferreira Martins-Filho, Laís Pereira Silva, Thiago Doria Barral, Stefanie Alvarenga Santos and Alessandra Estrela-Lima
    Citation: BMC Veterinary Research 2019 15:401
    Content type: Research article Published on:

  18. In horses a number of small intestinal diseases is potentially life threatening. Among them are Equine Grass Sickness (EGS), which is characterised by enteric neurodegeneration of unknown aetiology, as well as...

    Authors: Maria S. Unterköfler, Bruce C. McGorum, Elspeth M. Milne and Theresia F. Licka
    Citation: BMC Veterinary Research 2019 15:400
    Content type: Research article Published on:

  19. TBE is an important tick-borne viral zoonosis in Europe and some parts of Asia. Humans can become infected by tick bite and in some cases also by consumption of nonpasteurized raw milk and raw milk products fr...

    Authors: Christine Klaus, Ute Ziegler, Donata Hoffmann, Franziska Press, Christine Fast and Martin Beer
    Citation: BMC Veterinary Research 2019 15:399
    Content type: Research article Published on:

  20. Different tick species are able to transmit different pathogens, and tick-borne diseases are of substantial concern worldwide for both humans and animals. Environmental changes and changes in the range of tick...

    Authors: Agne Namina, Valentina Capligina, Maija Seleznova, Rudolfs Krumins, Darja Aleinikova, Agnija Kivrane, Sarmite Akopjana, Marija Lazovska, Inese Berzina and Renate Ranka
    Citation: BMC Veterinary Research 2019 15:398
    Content type: Research article Published on:

  21. Mild equine asthma is a common inflammatory airway disease of the horse. The primary treatment of mild equine asthma is corticosteroids. The purpose of this study was to investigate the effects of injected dex...

    Authors: Stephanie L. Bond, Jana Hundt and Renaud Léguillette
    Citation: BMC Veterinary Research 2019 15:397
    Content type: Research article Published on:

  23. Weight at birth is an important predictor of neonatal mortality and morbidity in dogs. In addition, the birthweight of the puppies in a litter influences the decision to perform a cesarean section. The goal of...

    Authors: Claude Schelling, Claude Gaillard, Jane Russenberger, Lou Moseley and Gaudenz Dolf
    Citation: BMC Veterinary Research 2019 15:395
    Content type: Research article Published on:

  24. Osteoarthritis (OA) affects nearly 20% of all dogs greater than one year of age. Clinical signs include pain, discomfort, lameness, and ultimately lead to disability. Although there is currently no known cure,...

    Authors: Diana M. A. Dewsbury, Keith D. DeDonder, Darrell J. Rezac and Natalia Cernicchiaro
    Citation: BMC Veterinary Research 2019 15:394
    Content type: Research article Published on:

  25. Canine parvovirus type 2 (CPV-2) is the most important enteric virus infecting canids. It is a rapidly evolving virus; after its emergence in the 1970s, new antigenic variants (called CPV-2a, 2b and 2c) emerge...

    Authors: Mara Battilani, Francesco Modugno, Francesco Mira, Giuseppa Purpari, Santina Di Bella, Annalisa Guercio and Andrea Balboni
    Citation: BMC Veterinary Research 2019 15:393
    Content type: Research article Published on:

  26. To report the occurrence of choroidal hypoplasia in the Australian Kelpie breed in Poland, the affected dogs testing positive for the Collie Eye Anomaly NHEJ1 gene mutation.

    Authors: Natalia Kucharczyk, Anna Cislo-Pakuluk and Peter Bedford
    Citation: BMC Veterinary Research 2019 15:392
    Content type: Case Report Published on:

  27. Food-producing animals can be a vehicle for staphylococcal species as well as their virulence and antimicrobial resistance genes. This work aimed to analyse the diversity of staphylococcal species in food-prod...

    Authors: Olouwafemi Mistourath Mama, Modou Dieng, Bocar Hanne, Laura Ruiz-Ripa, Codou Gueye Mar Diop and Carmen Torres
    Citation: BMC Veterinary Research 2019 15:391
    Content type: Research article Published on:

  28. Mammary cancer is a common disease affecting female dogs, where approximately 50% of the cases are malignant. There is a subpopulation of cancer cells with stem cell-like features within the tumour microenviro...

    Authors: Consuelo Serrano, Sofía Guzmán, Jose Ignacio Arias and Cristian Gabriel Torres
    Citation: BMC Veterinary Research 2019 15:390
    Content type: Research article Published on:

  29. Classic goose parvovirus (cGPV) causes high mortality and morbidity in goslings and Muscovy ducklings. Novel GPV (N-GPV) causes short beak and dwarfism syndrome (SBDS) in Cherry Valley ducks, Pekin ducks and M...

    Authors: Chunhe Wan, Cuiteng Chen, Longfei Cheng, Rongchang Liu, Shaohua Shi, Guanghua Fu, Hongmei Chen, Qiuling Fu and Yu Huang
    Citation: BMC Veterinary Research 2019 15:389
    Content type: Research article Published on:

  30. Clinical cases of Erysipelothrix rhusiopathiae, a zoonotic gram-positive bacterium, have been reported in many ruminant species, including in cattle, deer, moose and muskoxen. Fatal cases have been repeatedly rep...

    Authors: Ana I. Cubas Atienzar, Priscilla F. Gerber and Tanja Opriessnig
    Citation: BMC Veterinary Research 2019 15:388
    Content type: Research article Published on:

  31. Haemorrhagic enteritis (HE) of turkeys was first described in 1937 in the USA, while in Poland it was first diagnosed in 1987. Polish haemorrhagic enteritis virus (HEV) isolates are usually low pathogenic and ...

    Authors: Bartłomiej Tykałowski, Marcin Śmiałek, Andrzej Koncicki, Katarzyna Ognik, Zenon Zduńczyk and Jan Jankowski
    Citation: BMC Veterinary Research 2019 15:387
    Content type: Research article Published on:

  32. Platelet-rich plasma (PRP) as well as other platelet-derived products have been used as a potential disease-modifying treatment for musculoskeletal diseases, such as osteoarthritis (OA). The restorative proper...

    Authors: Livia Camargo Garbin, C. Wayne McIlwraith and David D. Frisbie
    Citation: BMC Veterinary Research 2019 15:386
    Content type: Research article Published on:

  33. Dogs with year-round atopic dermatitis are often sensitized to Dermatophagoides house dust mites (HDM). Storage mites (SM) are known to grow on cereal-rich foods. Tyrophagus SM can exacerbate clinical signs of al...

    Authors: Thierry Olivry and Ralf S. Mueller
    Citation: BMC Veterinary Research 2019 15:385
    Content type: Research article Published on:

  34. Pigmentary keratitis (PK) is commonly recognised in Pugs, but its aetiology is not completely understood. The aim of this study was to determine the prevalence and associated features of PK in Pugs in the Unit...

    Authors: S. Maini, R. Everson, C. Dawson, Y. M. Chang, C. Hartley and R. F. Sanchez
    Citation: BMC Veterinary Research 2019 15:384
    Content type: Research article Published on:

  35. Avian leukosis (AL), which is caused by avian leukosis virus (ALV), has led to substantial economic losses in the poultry industry. The kit used to detect all ALV-positive chickens in breeder flocks is very im...

    Authors: Xiaoyu Zhou, Lin Wang, Anning Shen, Xi Shen, Moru Xu, Kun Qian, Hongxia Shao, Yongxiu Yao, Venugopal Nair, Jianqiang Ye and Aijian Qin
    Citation: BMC Veterinary Research 2019 15:383
    Content type: Research article Published on:

  36. Topical antimicrobials are recommended for first line treatment of surface and superficial infections in dogs. This is especially important given the increasing prevalence of antimicrobial resistant infections...

    Authors: Rebecca Rafferty, Victoria H. Robinson, Jennifer Harris, Sally A. Argyle and Tim J. Nuttall
    Citation: BMC Veterinary Research 2019 15:382
    Content type: Research article Published on:

  37. Leishmaniosis, zoonosis that produces significant public health impacts, is caused by Leishmania infantum. Canines are the main domestic reservoir and, besides humans, other species of mammals could be infected w...

    Authors: Taiane Acunha Escobar, Gabriela Dowich, Thália Pacheco dos Santos, Luísa Zuravski, Claudia Acosta Duarte, Irina Lübeck and Vanusa Manfredini
    Citation: BMC Veterinary Research 2019 15:381
    Content type: Research article Published on:

  38. Cytotoxic T-lymphocyte antigen 4 (CTLA-4) is known as an immune inhibitory receptor that is expressed on activated effector T cells and regulatory T cells. When CTLA-4 binds to CD80 or CD86, immunoinhibitory s...

    Authors: Kei Watari, Satoru Konnai, Naoya Maekawa, Tomohiro Okagawa, Yasuhiko Suzuki, Shiro Murata and Kazuhiko Ohashi
    Citation: BMC Veterinary Research 2019 15:380
    Content type: Research article Published on:

  39. Canine idiopathic pulmonary fibrosis (CIPF) is a progressive interstitial lung disease mainly affecting old West Highland white terriers (WHWTs). The aetiology of CIPF is currently unknown and pathogenesis poo...

    Authors: Elodie Roels, Natali Bauer, Christelle Lecut, Andreas Moritz, André Gothot and Cécile Clercx
    Citation: BMC Veterinary Research 2019 15:379
    Content type: Research article Published on:

  40. The objective of this study was to investigate Brucella infection in farm animals in Saham, Oman, with reference to a survey carried out by the Ministry of Agriculture & Fisheries (MAF) for Brucellosis during the...

    Authors: Yasmin ElTahir, Anfal Al-Farsi, Waleed Al-Marzooqi, Alghalya Al-Toobi, Osman M. Gaafar, Maryne Jay, Yannick Corde, Shekar Bose, Abeer Al-Hamrashdi, Kaadhia Al-Kharousi, Sunil Rajamony, Muhammed Nadeem Asi, Nasseb Al-Saqri, Rudaina AlBusaidi, Elshafie I Elshafie and Eugene H. Johnson
    Citation: BMC Veterinary Research 2019 15:378
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Veterinary Research 2020 16:98

  41. Streptococcus suis is a prominent pathogen causing septicemia and meningitis in swine and humans. Bacitracin is used widely as a growth promoter in animal feed and to control the spread of necrotic enteritis in m...

    Authors: Jiale Ma, Jin Liu, Yue Zhang, Dan Wang, Runxia Liu, Guangjin Liu, Huochun Yao and Zihao Pan
    Citation: BMC Veterinary Research 2019 15:377
    Content type: Research article Published on:

  42. Inconsistency of treatment response in cats with obstructive hypertrophic cardiomyopathy is well recognized. We hypothesized that the difference in response to beta-blockers may be caused by myocardial functio...

    Authors: Ryohei Suzuki, Yohei Mochizuki, Yunosuke Yuchi, Yuyo Yasumura, Takahiro Saito, Takahiro Teshima, Hirotaka Matsumoto and Hidekazu Koyama
    Citation: BMC Veterinary Research 2019 15:376
    Content type: Research article Published on:

  43. Since 2016, incursions of highly pathogenic avian influenza virus (HPAIV) H5N8 clade 2.3.4.4b have caused unprecedented clinical signs and mortality in white-tailed eagles (WTE; Haliaeetus albicilla) across Europ...

    Authors: Megan Marie Lee, Veerle L. B. Jaspers, Mari E. Løseth, Nathalie Briels, Torgeir Nygård, Jan Ove Bustnes and Courtney A. Waugh
    Citation: BMC Veterinary Research 2019 15:375
    Content type: Research article Published on:

  45. Fowl adenovirus outbreaks have occurred in China since June 2015. This virus is an emerging infectious disease that causes hydropericardium syndrome and inclusion body hepatitis (HPS-IBH), resulting in signifi...

    Authors: Kai Wang, Haiwei Sun, Yunzhang Li, Zhiwei Yang, Jianqiang Ye and Hongjun Chen
    Citation: BMC Veterinary Research 2019 15:373
    Content type: Research article Published on:

  46. The stranding events of cetaceans in the Philippines provide opportunities for gathering biological information and specimens, especially from the pelagic forms. As part of an effort to monitor the health of w...

    Authors: Marie Christine M. Obusan, Ren Mark D. Villanueva, Maria Auxilia T. Siringan, Windell L. Rivera and Lemnuel V. Aragones
    Citation: BMC Veterinary Research 2019 15:372
    Content type: Research article Published on:

  47. Mycoplasma bovis is a causative agent of disease in cattle causing many clinical conditions. Currently there are no commercial M. bovis vaccines in Europe and treatment is difficult with decreased antimicrobial s...

    Authors: Katarzyna Dudek, Dariusz Bednarek, Roger D. Ayling, Anna Kycko and Michał Reichert
    Citation: BMC Veterinary Research 2019 15:371
    Content type: Research article Published on:

  48. The obligate intracellular bacterium Coxiella burnetii causes globally distributed zoonotic Q fever. Ruminant livestock are common reservoirs of C. burnetii. Coxiella burnetii are shed in large numbers in the was...

    Authors: Nataša Knap, Diana Žele, Urška Glinšek Biškup, Tatjana Avšič-Županc and Gorazd Vengušt
    Citation: BMC Veterinary Research 2019 15:368
    Content type: Research article Published on:

  49. The aim of this study was to investigate the association between plasma β-hydroxybutyric acid (BHBA) and conjugated linoleic acid in postpartum Polish Holstein-Friesian (PHF) cows. The experiment was carried o...

    Authors: Kamila Puppel, Marcin Gołębiewski, Paweł Solarczyk, Grzegorz Grodkowski, Jan Slósarz, Małgorzata Kunowska-Slósarz, Marek Balcerak, Tomasz Przysucha, Aleksandra Kalińska and Beata Kuczyńska
    Citation: BMC Veterinary Research 2019 15:367
    Content type: Research article Published on:

  50. Toxoplasma gondii, an intracellular apicomplexan protozoan parasite, can infect almost all warm-blooded animals. The aim of the present study was to investigate T. gondii oocyst-driven infection in pigs, chickens...

    Authors: Xiao-Yi Liu, Ze-Dong Wang, Saeed El-Ashram and Quan Liu
    Citation: BMC Veterinary Research 2019 15:366
    Content type: Research article Published on:
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