Fig. 6
From: Diverse roles of epidermal growth factors receptors in oral and cutaneous canine melanomas
Chromogenic in situ hybridization (CISH) for ERBB2 in canine melanoma. a) Cutaneous canine melanoma with normal expression (2–4 copies per cell) for ERBB2. b) Oral canine melanoma with normal expression (2–4 copies per cell) for ERBB2. c) Human mammary cancer cell line (positive control) with large clusters of ERBB2 in cancer cell nuclei. Arrows: Presence of chromogen. Arrow Head: melanin