Fig. 5

Heatmap representing binary comparisons per metabolic feature for the paired comparisons overtime in the control (a) and treatment (b) groups; and comparison treatment vs control group (c). Green sections of the heatmap denote metabolites that were reduced (negative log₂ fold-changes) and red sections denote metabolites that were increased (positive log₂ fold-changes); grey/black bars indicate significant changes with treatment (light grey, Student’s t-test p-value < 0.05; dark grey, p < 0.01; black, p < 0.001). Metabolites are grouped by families and ordered also according to their carbon number and unsaturation degree of their acyl chains