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Table 7 The intestinal nutrients transporter genes of growing pigs fed with Deoxynivalenol (DON)-contaminated corn (n = 6)

From: Growth performance, serum biochemical profile, jejunal morphology, and the expression of nutrients transporter genes in deoxynivalenol (DON)- challenged growing pigs

Item

Control

3 mg/kg DON

6 mg/kg DON

12 mg/kg DON

P-value

EAAT-3

1 ± 0.06a

0.84 ± 0.11a,b

0.69 ± 0.17b

0.61 ± 0.21b

0.0011

B0,+AT

1 ± 0.15

0.92 ± 0.21

0.73 ± 0.26

0.75 ± 0.21

0.1057

SGLT-1

1 ± 0.08a,b

1.02 ± 0.13a

0.76 ± 0.15b,c

0.72 ± 0.23c

0.0044

GLUT-2

1 ± 0.08

0.86 ± 0.15

0.78 ± 0.05

0.81 ± 0.25

0.0956

PepT-1

1 ± 0.12a,b

1.09 ± 0.13a

0.87 ± 0.09b

0.79 ± 0.16b

0.0028

ASCT-2

1 ± 0.19

0.94 ± 0.24

0.98 ± 0.07

0.82 ± 0.2

0.3625

CAT-1

1 ± 0.15a

0.81 ± 0.15a

0.48 ± 0.06b

0.5 ± 0.18b

<0.0001

LAT-1

1 ± 0.07a

0.89 ± 0.19a

0.41 ± 0.06b

0.46 ± 0.09b

<0.0001

  1. Results are expressed as means ± SEM for six animals
  2. EAAT-3: excitatory amino acid transporter-3, B0,+AT: b0,+amino acid transporter, SGLT-1: sodium-glucose transporter-1, GLUT-2: glucose transporter-2, PepT-1: dipeptide transporter-1, ASCT-2: Na+-dependent neutral amino acid exchanger-2, CAT-1: cationic amino acid transporter-1, LAT-1: y+L-type amino acid transporter-1
  3. a–cValues with different letters within the same row are significantly different (P < 0.05)