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Table 1 Detection of the blood biochemical parameters

From: PD-1/PD-L1 axis induced host immunosuppression via PI3K/Akt/mTOR signalling pathway in piglets infected by Glaesserella Parasuis

Item

Control

24 h GPS

48 h GPS

72 h GPS

SEM

P value

(A)

(B)

(C)

(D)

B vs. A

C vs. B

D vs. B

T-Bil(µmol/L)

3.01

3.85

10.10

3.74

1.01

< 0.001

< 0.001

< 0.001

TP(g/L)

46.80

43.90

45.17

46.01

0.48

0.041

0.207

0.526

ALB(g/L)

27.24

24.08

22.20

20.78

0.75

0.001

< 0.001

< 0.001

AST(U/L)

65.00

121.00

115.00

192.00

14.05

0.001

0.001

< 0.001

ALT(U/L)

41.00

36.00

23.00

19.00

2.95

0.279

0.002

0.001

ALP(U/L)

577.00

373.00

296.00

266.00

46.93

0.068

0.020

0.013

TC(mmol/L)

1.81

1.21

1.12

1.09

0.11

0.032

0.018

0.015

TG(mmol/L)

0.32

0.32

0.25

0.39

0.02

0.868

0.005

0.007

GLU(mmol/L)

4.50

2.60

2.10

0.47

0.44

< 0.001

< 0.001

< 0.001

Ca(mmol/L)

2.23

2.03

2.04

2.31

0.05

0.096

0.110

0.479

IP(mmol/L)

2.85

3.00

2.87

2.76

0.04

0.110

0.817

0.313

CRE(µmol/L)

92.72

90.26

76.06

52.77

4.81

0.155

< 0.001

< 0.001

HDL-C(mmol/L)

0.56

0.13

0.21

0.18

0.05

< 0.001

< 0.001

< 0.001

LDL-C(mmol/L)

0.98

0.47

0.55

0.50

0.08

0.011

0.023

0.014

UA(µmol/L)

2.67

4.58

10.29

5.84

1.72

0.129

< 0.001

0.023

γ-GT(U/L)

68.00

56.00

43.00

35.00

3.92

0.004

< 0.001

< 0.001

CK(U/L)

912.00

692.00

690.00

515.00

45.09

0.002

0.002

< 0.001

D-Bil(µmol/L)

0.47

1.99

5.57

2.42

0.57

0.001

< 0.001

< 0.001

LDH(U/L)

1067.90

1067.00

1359.20

1501.90

76.39

0.994

0.042

0.007

  1. GPS G. parasuis