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Table 3 Effect of i/p injection of fructose (2.75 mM) and TiO2 NPS (100 mg/Kg) on oxidative stress and antioxidant biomarkers of in-vitro matured mice oocytes: (In-vivo study)

From: Fructose improves titanium dioxide nanoparticles induced alterations in developmental competence of mouse oocytes

Treatment

n

NO (mmol/L)

GPx (mmol/L)

GSH (mmol/L)

MDA (mmol/L)

TAC (mmol/L)

Control (G1)

168

54.39 ± 0.44a

386.15 ± 4.61c

4.74 ± 0.47a

7.86 ± 0.04c

0.16 ± 0.001c

TiO2 NP (G2)

160

42.89 ± 0.21c

783.77 ± 5.53a

3.13 ± 0.18c

9.72 ± 0.03a

0.50 ± 0.02a

TiO2 NP + Fructose (G3)

142

51.93 ± 0.42b

433.52 ± 25.77b

3.50 ± 0.03b

9.07 ± 0.11b

0.25 ± 0.02b

  1. Means with different superscripts (a, b, c, d) are different (p < 0.05). Values are presented as means ± SEM
  2. Abbreviations n = number of oocytes; NO = nitric oxide; GPx = Glutathione peroxidase (GPx); GSH = Glutathione; MDA = Malondialdehyde acetate; TAC = Total antioxidant capacity, TiO2NP = titanium dioxide nanoparticles