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Table 1 Determination of the LD50 in PmCQ2 and PmCQ2Δ4555–4580

From: Attenuated vaccine PmCQ2Δ4555–4580 effectively protects mice against Pasteurella multocida infection

PmCQ2

Infection dose (CFU)

75

19

5

2

1

Euthanized/total mice

8/8

8/8

7/8

6/8

5/8

LD50 = 0.692 CFU

PmCQ2Δ4555–4580

Infection dose (CFU)

7.57 × 109

3.79 × 109

1.89 × 109

9.46 × 108

4.73 × 108

Euthanized/total mice

8/8

7/8

5/8

0/8

0/8

  1. LD50 = 1.941 × 109 CFU