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Table 1 Hemagglutination activity of NDV after mixing with α-sitosterol

From: Alpha-sitosterol: a new antiviral agent produced by Streptomyces misakiensis and its potential activity against Newcastle disease virus

α-Sitosterol

RBCs concentration (%)

Hemagglutination activity of NDV (log2)

β

P-value

Means (log2) ± SD

V/V

1/2

1/4

1/8

Before SPF-ECE inoculation

0.5%

Zero

Zero

Zero

Zero

–

–

–

0.75%

22

Zero

Zero

Zero

- 0.500

0.001

1.00 ± 0.00

After SPF-ECE inoculation

0.5%

27

25

23

Zero

−1.161

0.001

1.953 ± 0.521

0.75%

29

27

25

Zero

−1.403

0.001

2.564 ± 0.343

  1. PBS Phosphate buffered saline: SPF-ECE Specific pathogen free-embryonated chicken egg: β: the regression coefficient. Zero indicates precipitation of RBCs. SD standard deviation: HA of original strain 8 log2 and 9 log2 with RBCs 0.5 and 0.75%, respectively. The P-value of NDV after being treated α-Sitosterol was revealed significant effects (P < 0.0001) on the hemagglutination activity with both two concentrations of RBCs (0.5 and 0.75%)
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BMC Veterinary Research

ISSN: 1746-6148

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