Table 4 Comparison of plasma BCL pharmacokinetic parameters after single-dose oral administration of AMO-RSE powder and RSE powder (BCL 5 mg/kg) (n = 6)

λ_z (1/h)

0.110

0.061

0.094

0.061

0.670

t_1/2λ (h)

7.615

2.921

9.210

3.758

0.432

AUC_0-∞ (µg·h/mL)

6.978

1.698

5.357

1.454

0.107

MRT_0-∞ (h)

11.520

3.775

12.433

5.045

0.731

C_max (µg/mL)

0.632

0.222

0.730

0.348

0.575

T_max (h)

Median

Range

Median

Range

1.833

0.33 ~ 4.00

1.194

0.33 ~ 2.00

0.436