Fig. 4

Cardiac rhabdomyosarcoma at the border with myocardial tissue; immunohistochemistry with antibodies: anti- desmin, anti-vimentin and antimyoglobin. Normal heart muscle is visible on the left, tumor tissue on the right. Visible infiltration of tissues one into the other. A. Desmin- multifocal strong cytoplasmic expression of desmin is visible in neoplastic cells and in normal cardiomyocytes. B. Vimentin- mild to strong cytoplasmic expression is visible in neoplastic cells and absent of expression in normal cardiomyocytes. C. Myoglobin mild to strong cytoplasmic expression is visible in neoplastic cells and in normal cardiomyocytes