Fig.7

Liver of rabbit infected with E.steadie non–treated sporulated oocysts A showing proliferation, marked enlargement of bile ducts, extensive hyperplasia of the biliary epithelium forming multiple long papillary projections (arrows) (H&E, X40). B Showing invasion of the papillomatous proliferation of biliary epithelium with numerous and various developmental stages of the coccidian parasite (arrows) (H&E, X100). C Showing the cystic formation of the bile duct associated with the presence of massive numbers of oval non-sporulated oocysts (stars), and cellular debris within the lumen. (H&E,X100). D Higher magnification of figure C (H&E, X200). E Showing extensive peribiliary fibrosis (black arrow) associated with infiltration of mononuclear cells (yellow arrow), in addition to necrosis of hepatocytes (arrow head) (H&E, X100). F Showing multiple small scattered areas of hemorrhages in hepatic parenchyma associated with fibrosis and severe degenerative and necrotic changes of hepatocytes (yellow arrow) (H&E, X100). G Showing high dilatation and congestion of central vein (star) and sinusoids associated with necrosis of endothelial cells lining and centrilobular fibrous C.T. proliferation (black arrow) in addition to necrosis of hepatic cells (yellow arrow) and lymphocytic cell infiltration. (H&E, X100)