Fig. 1From: Low alanine aminotransferase activity gene variant in a Siberian Husky with copper-associated hepatopathyRepresentative photomicrographs of the dog’s liver biopsy sample. (A) High-power image of a hematoxylin and eosin stained histologic section of the patient’s liver, demonstrating a necrotic cell with hypereosinophilic cytoplasm (arrow). Note cytoplasmic pigment in the necrotic and adjacent hepatocytes. (B & C) Rhodanine staining at low (B) and high (C) power confirmed the pigment represented copperBack to article page