Blood metabolomics reveals the therapeutic effect of Pueraria polysaccharide on calf diarrhea

BMC Veterinary Research

Table 3 Effects of PPL on scores of clinical symptoms

Items	Treatment	Group				SEM
Items	Treatment	Low dose	Medium dose	High dose	Control	SEM
Fecal scores	D0	2.17_a^a	2.33_a^a	2.08_a^a	0.00^b	0.114
	D1	1.33_b,c^a	1.58_b^a	1.50_b^a	0.25^b	0.165
	D2	1.42_b^a	1.25_b,c^a	1.08_b,c^a	0.08^b	0.139
	D3	1.08_b,c^a	1.08_b^a	1.33_b^a	0.17^b	0.169
	D4	1.17_b,c^a	1.00_b^a	1.00_b,c^a	0.17^b	0.211
	D5	1.25_b,c^a	1.00_b^a	1.17_b^a	0.08^b	0.209
	D6	0.75_b,c^a	0.42_c^a,b	0.58_c,d^a	0.00^b	0.148
	D7	0.58_c^a	0.25_c^a,b	0.33_d^a,b	0.08^b	0.165
	P (dose)	< 0.001
	P (time)	< 0.001
	P (dose × time)	< 0.001
Dehydration scores	D0	1.17_a^a	1.25_a^a	1.25_a^a	0.00^b	0.093
	D1	0.42_b^a	0.50_b^a	0.58_b^a	0.00^b	0.112
	D2	0.25_b	0.25_b,c	0.17_c	0.00	0.093
	D3	0.33_b	0.08_c	0.09_c	0.00	0.089
	D4	0.30_b	0.00_c	0.00_c	0.00	0.036
	D5	0.38_b^a	0.00_c^b	0.00_c^b	0.00^b	0.058
	D6	0.25_b	0.00_c	0.00_c	0.00	0.045
	D7	0.17_b	0.00_c	0.00_c	0.00	0.042
	P (dose)	< 0.001
	P (time)	< 0.001
	P (dose × time)	< 0.001
Mental scores	D0	0.25^a	0.58_a^b	0.17^a	0.00^a	0.109
	D1	0.25	0.17_b	0.25	0.00	0.093
	D2	0.08	0.17_b	0.17	0.00	0.077
	D3	0.08	0.17_b	0.25	0.00	0.082
	D4	0.33^a	0.00_b^b	0.08^b	0.00^b	0.056
	D5	0.17	0.17_b	0.25	0.00	0.089
	D6	0.08	0.08_b	0.17	0.00	0.070
	D7	0.08	0.08_b	0.17	0.00	0.070
	P (dose)	0.250
	P (time)	0.0002
	P (dose × time)	0.338

For each indicator, different superscripted letters represent significant differences between different groups at the same time point (P < 0.05), while different subscripted letters represent significant differences with in one group between different time points (P < 0.05)

ISSN: 1746-6148