CelCradle (Lot D) | BioFactory (1-layer) | |
---|---|---|
Cell seeding density (104 cells/ml) | 8.60 | 14.80 |
Cell doubling time (h) | 35.52 | 37.14 |
Maximum cell number (108 cells/bottle or 108 cells/layer) | 4.47 ± 0.63 | 1.33 ± 0.52 |
Maximum cell concentration (105 cells/ml) | 8.94 ± 1.26 | 8.87 ± 3.47 |
Cell number at time of infection (105 cells/ml) | 8.94 ± 1.26 | 8.87 ± 3.47 |
Multiplicity of infection (MOI) | 0.01 | 0.01 |
Viral titer (107 TCID50/ml) | 20.40 ± 5.80 | 8.15 ± 0.79 |
Total virus production (1010 TCID50/bottle or 1010 TCID50/layer) | 10.20 ± 2.90 | 1.02 ± 0.10 |
Cell-specific infectious virus yield (TCID50/cell)a | 228 | 77 |