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Table 1 Median (range) serum concentrations of acute phase proteins in healthy dogs and in dogs with pyometra and pancreatitis

From: Divergences between serum C-reactive protein and ferritin concentrations in canine pyometra

Protein, unit

(RI)

Healthy

(n = 25)

Pyometra

(n = 25)

Pancreatitis

(n = 25)

P*

CRP, mg/L

(1–12 mg/L)

5.3

(1.3–7.5)

118.0a

(54.0–354.6)

71.5a

(40.4–265.0)

< 0.001

Ferritin, µg/L

(60–190 µg/L)

149.0

(81.0–187.0)

134.0c

(40.0–303.0)

465.5a

(136.0–3121.0)

< 0.001

Hp, g/L

(1–3 g/L)

2.1

(1.4–2.8)

4.2b

(2.7– 5.7)

4.3b

(0.1– 4.9)

0.002

Albumin, g/dL

(2.5–3.6 g/dL)

3.2

(2.6–3.5)

2.5a

(1.8–3.3)

2.2a

(1.3–3.0)

< 0.001

PON1, IU/L

(3–4.3 IU/L)

4.0

(3.2–4.3)

2.6a

(1.2–4.4)

2.5a

(1.6–4.5)

< 0.001

  1. *Kruskal-Wallis test
  2. Letters indicate statistical significance between groups obtained with Dunn’s multiple comparisons test: a, P < 0.001 vs. healthy; b, P < 0.01 vs. healthy; c, P < 0.001 vs. pancreatitis group
  3. CRP, protein reactive C; Hp, haptoglobin; PON1, paraoxonase. RI, reference intervals. RIs of all APPs have been calculated using data of 50 healthy adult dogs