Table 1 Power calculations for the primary hypothesis
Power | Treatment, assumed % | Placebo, assumed % | Assumed difference in % | Non-inferiority margin | n/group |
|---|---|---|---|---|---|
80% | 1% | 2% | 1% | 7% | 51 |
80% | 1% | 3% | 2% | 7% | 97 |
79% | 1.33% | 2.67% | 1.33% | 7% | 75 |
47% | 1.33% | 4% | 2.7% | 7% | 75 |
98% | 1.33% | 1.33% | 0% | 7% | 75 |
84% | 2.67% | 2.67% | 0% | 7% | 75 |
70% | 4% | 4% | 0% | 7% | 75 |