Fig. 11

Intramammary infusion of bMSC in normal lactating dairy cows. Rectal temperature (A), milk production (B), total blood white cell counts (WCC in C), and SCC (D) were recorded prior to intramammary (IMM) bMSC treatment and 8 hourly thereafter. Representative microscopic images of formalin-fixed paraffin-embedded H&E stained tissue sections from control quarters (E–G) and bMSC-treated quarters (H-J). Quarters treated with bMSC demonstrated considerable elevation of SCC while control quarters showed only mild increase (D). Histopathological examination of bMSC treated quarters revealed sparse infiltration of neutrophils into the parenchyma (white arrow in J) and rare alveoli infiltrated with neutrophils (black arrows in H-J). Scale bars, 200 µm (E&H), 100 µm (F&I) and 50 µm (G&J)