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Table 1 Data summary of coagulation profiles

From: Dose-dependent effect of canine lyophilized platelet on an in vitro hemodilution model

 

Control

Group 1

Group 2

Group 3

Fibrinogen (mg/dl)

76 (55–89)

78 (63–94)

77 (62–97)

81 (60–96)

PT (sec)

9.05 (8.6–9.3)

9.1 (8.7–9.5)

9.15 (8.8–9.5)

9.05 (8.9–9.4)

aPTT (sec)

32.5 (28.9–37.0)

27 (25.1–32.4)

24.6 (21.9–27.3)*

24.7 (19.3–30.3)*

TEG

R time (min)

4.1 (2.8–5.2)

2.15 (1.5–2.8)*

1.8 (1.1–2.5)*

1.75 (1.3–2.1)*

K time (min)

0

0 (0-7.8)

0 (0-4.5)

3.5 (0–7)

Angle (°)

34.3 (21.1–58.3)

49.7 (37.1–67.1)*

54.5 (44.3–70)*

54.7 (42.6–64.6)*

MA (mm)

8.7 (3.1–16.1)

11.2 (6.1–23.4)

15.4 (10-24.6)*

25.2 (172 − 31.5)*#

Ct (sec)

210 (139–287)

169 (131–219)

160 (139–195)

145 (118–162)*

  1. Data are expressed as the median (range). *Asterisk indicates a significant difference compared to the Control group (p < 0.05). #Hash indicates a significant difference compared to the Group 2 (p < 0.05). Statistical analysis was not performed for K times due to the insufficient amount of data. No lyophilized platelets were added to the control group. The canine lyophilized platelets were added to the amount that could increase the platelet count by 25 (Group 1), 50 (Group 2), and 100 (Group 3) ×106/ml
  2. PT = prothrombin time; aPTT = activated partial thrombin time; MA = maximum amplitude; Ct = closure time; plts = platelets