Fig. 4

Feline injection site fibrosarcomas. A Mean IRS for MT expression values in tumours grade I, II, and III. The IRS for MT expression was significantly higher in tumours grade I compared to grade II (p = 0.04) and III (p = 0.012). B Negative correlation between the IRS for MT expression and the tumour grade. The metallothionein expression decreased as the tumour grade was higher (r = -0.356; p = 0.024). C Negative correlation between the IRS for MT expression and the inflammation score. The metallothionein expression decreased as the inflammation score was higher (r = -0.713; p = 0.000). D No correlation was found between IRS for MT expression and necrosis score (r = 0.014; p = 0.9)