Fig. 13

Miniature pig bullosa pemphigoid: a Vesicles and small bullae are present in a crop on the back with mild scaling. b Large bullae on the back are present next to a circular area of partial depigmentation that is bordered by a rim of hyperpigmentation and scaling, which is a site of a previously healed bulla. c Grouped erosions and shallow ulcers are sites of ruptured bullae and are well demarcated, circular, mildly crusted, and bordered by mild scaling and a rim of hyperpigmentation. d Low magnification histologic image of a bulla demonstrates subepidermal clefting. e and f Higher magnification images of the bulla in image “d” showing subepidermal clefting, eosinophils, neutrophils, and fibrin within the lumen of the bulla and a perivascular infiltrate of predominately eosinophils in the dermis. Haematoxylin and eosin