Lesion | Control group | β-1,3-glucan supplemented group | Fipronil and lead exposed group | Combined fipronil and lead, and β-1,3-glucan supplemented group |
---|---|---|---|---|
Depletion and necrosis in the lymphocytes of white pulp | _ | _ | ++ | _ |
Hemorrhagic red pulp | _ | _ | ++ | _ |
Hemosiderosis | _ | _ | ++ | + |
Blood vessels dilatation with congestion in red pulp | _ | _ | ++ | _ |
Proliferation and regeneration of splenic white pulp with activated melano- macrophages centers | _ | _ | _ | ++ |