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Table 4 Semi-quantitative histopathological lesions score in the spleen of the different catfish experimental groups

From: β-1,3-glucan improved the health and immunity of juvenile African catfish (Clarias gariepinus) and neutralized the histological changes caused by lead and fipronil pollutants

Lesion

Control group

β-1,3-glucan

supplemented group

Fipronil and lead exposed group

Combined fipronil and lead, and β-1,3-glucan supplemented group

Depletion and necrosis in the lymphocytes of white pulp

_

_

++

_

Hemorrhagic red pulp

_

_

++

_

Hemosiderosis

_

_

++

+

Blood vessels dilatation with congestion in red pulp

_

_

++

_

Proliferation and regeneration of splenic white pulp with activated melano- macrophages centers

_

_

_

++