Fig. 2

Establishment of the model of KM mice infected with PCV2. a The Cap gene in tissues and blood of mice was determined after 5dpi. with PCV2 by PCR. M indicated the Marker, K indicated the normal mice and mumber 1–5 indicated individual PCV2 infected mouse. b HE staining results of the mice lungs showed that, compared with the normal group, the pulmonary interstitium of the PCV2 group was significantly widened and the alveolar cavity was significantly reduced. c The qPCR results showed that the highest expression of Cap gene in the liver was obsevered. d-f body weight gain, lung index and spleen index. Compared with the normal control group, there was no significant difference in the weight gain rate and lung index in the PCV2 infection group, while the spleen index increased significantly. ***means p < 0.001. Different letters indicated significant differences between the groups, p < 0.05