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Table 5 Clinical scores, lung lesions and M. hyopneumoniae (Mhyop) counts in the lungs in the dual challenge study in piglets. All piglets were challenged with M. hyopneumoniae on days 0, 1 and 3 and with PRRSV on day 14. Pigs in treated-challenged group were medicated daily with tylvalosin at 20 mg/kg body weight from day 10 to day 20. Treatement description is in Table 5

From: Effects of a water-soluble formulation of tylvalosin on disease caused by porcine reproductive and respiratory syndrome virus alone in sows or in combination with Mycoplasma hyopneumoniae in piglets

Group

n

Clinical scores

Lung scores mean ± SD

Mhyop isolation

Day 14

Day 24

Consolidation

Congestion

N positive (%)

Mean colony forming units (cfu)/mL ± SD

Treated- challenged

7

0.5 ± 0.53

3.1 ± 1.86

14.7 ± 10.0

66.7 ± 24.9

0 (0%)

0

Untreated-challenged

7

1.0 ± 1.15

2.9 ± 2.19

22.1 ± 11.0

57.6 ± 21.0

All (100%)

2.68 × 104 ± 2.72 × 104

P-value

0.261

0.833

0.184

0.431

Not compared

0.023