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Fig. 5 | BMC Veterinary Research

Fig. 5

From: A PK/PD model for the evaluation of clinical rifaximin dosage for the treatment of dairy cow mastitis induced by Escherichia coli

Fig. 5

The probability distribution of AUC/MIC for rifaximin using a 10,000-subject Monte Carlo analysis based on the measured PK parameters obtained following mammary gland injection at 100 mg/gland with 24-h (a and b), 12-h (c and d) and 8-h (e and f) dosing interval in dairy cows and E. coli MIC distribution in this study. The areas of blue columns represent the probability of target attainment (PTA) for the 2log10CFU/gland decrease and the 2.5log10CFU/gland decrease of E. coli

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