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Table 3 Scoring of fibrinosuppurative lesions of piglets challenged with 2 × 108 CFU of S. suis strain 16667/3

From: A new S. suis serotype 3 infection model in pigs: lack of effect of buprenorphine treatment to reduce distress

buprenorphine

piglets without lesionsa

piglets with lesions in two or more locationsa

brain

serosae

joint

spleen and liver

lung

heart

meningo-encephalitis, chorioiditis

pleuritis or peritonitisg or pericarditis

arthritis

splenitisb or hepatitis

pneumonia

endocarditis

 

5c

3d

1e

4c

2d

1e

4c

2d

1e

4c

2d

1e

4c

2d

1e

4c

2d

1e

ωf

untreated

4/8

1 h/8

1i/8

0/8

1/8

0/8

0/8

0/8

0/8

2/8

0/8

0/8

0/8

0/8

0/8

0/8

1/8

0/8

1/8

0/8

1.6

treated

5/8

2 h/8

2i/8

0/8

0/8

0/8

0/8

0/8

1/8

1/8

0/8

0/8

0/8

0/8

0/8

0/8

0/8

1/8

0/8

0/8

2.5

  1. aOnly fibrinosuppurative lesions are considered. Individual single perivascular neutrophils are not counted
  2. bNeutrophilic accumulation of the splenic red pulp
  3. cScoring of 4 and 5 indicates moderate to severe diffuse or oligo-/multifocal fibrinosuppurative inflammations
  4. dScoring of 2 and 3 indicates mild focal or multifocal fibrinosuppurative inflammation
  5. eIndividual single perivascular infiltration with neutrophils received a score of 1
  6. fω = Σscoremax/nanimals
  7. gPeritoneum is missing from one animal of each group
  8. hFibrinosuppurative lesions in two or more joints
  9. iFibrinosuppurative lesions in several brain areas and the plexus choroideus