CELL TYPE | GENE FUNCTION | Â | Â | Â |
---|---|---|---|---|
 | Proliferation regulators | Signaling | Transcription factors | Extracellular matrix |
AT-MSCs | Up-regulated BARD1 (-) BRCA1†(-) CASP8 (-) CLU ( +) LOC100146270 (-) PCNA ( +) PDGFD ( +) | Up-regulated MET |  | Up-regulated DMP1 |
Down-regulated CRTAC1 SMDP3†| ||||
BM-MSCs | Up-regulated BARD1 (-) BRCA1†(-) CASP8 (-) CCND1 ( +) CDKN1A (-) CTNNB1 ( +) GLB1†(-) HDGF ( +) LOC100146270 (-) MYC ( +) PCNA ( +) PHB (-) TGFA ( +) TP53†(-) | Up-regulated GDF6 PHEX | Up-regulated BMP4 BMP7 TGFB3 | Up-regulated COL4A1 DMP1 LOC100146589 |
Down-regulated BCL2 ( +) CLU ( +) IGF1†( +) PDGFD ( +) | Down-regulated ALPL†ABI3BP FGFR3 IGFBP5 MIA†S100A1 TNFRSF11B | Down-regulated BMP6 SNAI2†| Down-regulated ACAN CHADL COL1A1 COL9A2 COL11A1 COL12A1 COMP MMP13†SMPD3†SPARC | |
DFs | Down-regulated BCL2 ( +) CCND1 ( +) CTGF ( +) HGF ( +) TP53†(-) | Down-regulated GDF6 TIMP2 SMOC1 | Down-regulated GLI3 RUNX3 | Down-regulated ACAN COL5A3 SMPD3†|