A novel strategy for developing vaccine candidate against Jaagsiekte sheep retrovirus from the envelope and gag proteins: an in-silico approach

Table 3 Physical and chemical properties, antigenicity, and number of the predicted transmembrane helices of Jaagsiekte sheep retrovirus proteins

Accession number	Protein name	MW	II^a	AI	pI	L	EC	GRAVY^b	VA ^c	TMHs
*P31621*	Envelope protein	69.34	36.84	99.09	8.57	615	105,770	-0.021	0.6007	Yes/4
*P31622*	Gag protein	68.08	47.03	70.82	7.16	612	78,840	-0.542	0.5465	Yes/1
*P31625*	Neutral protease large subunit	31.31	27.87	98.86	8.9	289	44,920	-0.094	0.4948	Yes /1
*P31623*	Pol protein	88.69	40.83	88.01	5.55	777	115,170	-0.227	0.4876	Yes/1
*P31624*	Hypothetical protein	19.35	38.39	138.49	8.57	166	16,960	0.81	0.4876	Yes/4

MW Molecular weight (kilodalton), AI Aliphatic index, pI Theoretical isoelectric point, L Length of the protein, EC Extinction coefficient
^aII: instability index < 40 considered the protein stable
^bGRAVY negative sign indicated the protein is hydrophilic
^cVaxijen antigenicity with a default threshold of 0.4. THMs: Transmembrane helices

ISSN: 1746-6148