Table 3 The result of cell survival rate (% reduction of AlamarBlue) of different primary cells derived from feline injection site sarcomas (FISSs) following treatment with different concentrations of 5-hydroxy-9,10-dioxo-9,10-dihydroanthracene-1-sulfonamide (LLL12) for 1-3 days
| Â | FISS-10 | Â | Â | Â | Â | Â | FISS-14 | Â | Â | Â | Â | Â |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
LLL12 | day 1 | Â | day 2 | Â | day 3 | Â | day 1 | Â | day 2 | Â | day 3 | Â |
(μM) | Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD |
2 | 31.892 | 0.186 | 23.754 | 0.242 | 32.665 | 0.177 | 11.279 | 0.585 | 17.964 | 0.399 | 14.257 | 0.482 |
1 | 37.898 | 0.594 | 23.494 | 0.151 | 32.586 | 0.160 | 15.272 | 0.580 | 16.165 | 0.297 | 14.692 | 0.244 |
0.5 | 39.305 | 1.025 | 25.812 | 0.562 | 34.366 | 0.192 | 41.122 | 2.812 | 69.744 | 3.587 | 57.243 | 3.394 |
0.25 | 60.345 | 1.347 | 49.953 | 0.939 | 56.049 | 0.736 | 46.300 | 14.753 | 79.969 | 16.165 | 88.842 | 3.645 |
0.125 | 71.976 | 1.316 | 67.882 | 2.125 | 90.040 | 1.662 | 62.514 | 10.629 | 139.298 | 1.913 | 109.572 | 3.076 |
DMSO | 122.028 | 1.679 | 121.097 | 3.457 | 159.510 | 4.100 | 104.645 | 6.453 | 161.766 | 3.668 | 98.890 | 22.530 |
0 | 100.000 | 1.952 | 100.000 | 3.845 | 100.000 | 9.086 | 100.000 | 2.012 | 100.000 | 21.695 | 100.000 | 9.935 |