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Fig. 3 | BMC Veterinary Research

Fig. 3

From: Evaluation of endothelial cell-specific molecule-1 as a biomarker of glycocalyx damage in canine myxomatous mitral valve disease

Fig. 3

Factors affecting serum ESM-1 concentration. A The hypertensive group showed significantly high ESM-1 concentration compared to the normotensive group (p < 0.01). Unit of pressure is mmHg in the table. SBP was classified into normotensive (< 140 mmHg), prehypertensive (140 ~ 159 mmHg), and hypertensive (≥ 160 mmHg) according to ACVIM hypertension consensus (2018), B When classified as VHS, group above 11.5 v showed significantly increased ESM-1 concentration compared to group under 11.5 v (p < 0.05). VHS 11.5, which is considered as general breed cardiomegaly, was used as a cut-off point. C Group taking sildenafil showed significantly high ESM-1 concentration compared to a group not taking sildenafil (p < 0.05). Abbreviations: ESM-1, endothelial cell-specific molecule-1; VHS, vertebral heart score

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BMC Veterinary Research

ISSN: 1746-6148

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