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Table 1 Change rates of chest and waist circumferences (%)

From: Evaluation of safety and anti-obesity effects of DWP16001 in naturally obese dogs

Weeks

OC

DWP0.2

DWP0.5

DWP1

Change rates of chest circumferences (%)

 0

100.00 ± 0.00

100.00 ± 0.00

100.00 ± 0.00

100.00 ± 0.00

 2

99.39 ± 3.13

99.20 ± 3.44

98.19 ± 4.31

94.79 ± 6.67

 4

99.64 ± 3.44

97.16 ± 2.74

97.16 ± 3.23

99.81 ± 2.43

 6

96.92 ± 5.74

95.08 ± 3.96

95.60 ± 4.55

100.54 ± 4.98

 8

96.99 ± 4.44

96.08 ± 2.60

93.90 ± 3.11

99.20 ± 4.49

 10

99.52 ± 6.24

99.18 ± 3.01

96.43 ± 2.76

100.24 ± 5.15

Change rates of waist circumferences (%)

 0

100.00 ± 0.00

100.00 ± 0.00

100.00 ± 0.00

100.00 ± 0.00

 2

101.93 ± 8.89

100.53 ± 4.71

99.57 ± 1.71

95.97 ± 11.67

 4

104.05 ± 6.64

97.39 ± 12.15

98.45 ± 4.94

99.18 ± 8.09

 6

96.08 ± 7.08

98.96 ± 15.47

96.30 ± 3.83

103.75 ± 10.54

 8

102.61 ± 6.40

98.89 ± 11.98

93.84 ± 5.54

99.76 ± 12.53

 10

103.54 ± 2.93

101.98 ± 10.78

96.00 ± 4.72

101.33 ± 14.44

  1. Data are expressed as Mean ± S.D
  2. OC Obese normal control, DWP0.1 DWP16001 0.2 mg/kg/day, DWP0.2 DWP16001 0.5 mg/kg/day, DWP1 DWP16001 1 mg/kg/day
  3. *A significant difference at p < 0.05 level compared to the OC