Topical applications of allogeneic adipose-derived mesenchymal stem cells ameliorate the canine keratoconjunctivitis sicca

Table 6 The numeric rating scale (NRS) of clinical signs

Mucoid discharge	5 = severe	Mucopurulent crust, stinky
	4 = advanced	Yellowish, mucoid discharge, smelly
	3 = moderate	Yellowish, sticky discharge
	2 = lightly	Clear, but discharge volume increased
	1 = normal	Absent discharge
Conjunctival hyperemia	5 = severe	Diffuse beefy red
	4 = advanced	Individual vessels not easily discernible
	3 = moderate	More diffuse, deeper crimson red
	2 = lightly	Vessels definitely injected above normal
	1 = normal	Vessels normal
Corneal change	5 = severe	Opaque, iris invisible with pigmentation, keratitis
	4 = advanced	Opalescent areas, no details of iris visible
	3 = moderate	Easily discernible translucent area, details of iris slightly obscured
	2 = lightly	Scattered or diffuse areas, details of iris clearly visible
	1 = normal	No opacity

The NRS score was a five-point scale used to access the severity of mucoid discharge, conjunctival hyperemia, and corneal changes by dog owners and the veterinarian

ISSN: 1746-6148