Skip to main content

Table 1 Changes in hemodynamic variables at various right atrial pacing rates in 8 healthy anesthetized dogs

From: Influence of heart rate on right ventricular function assessed by right heart catheterization and echocardiography in healthy anesthetized dogs

Variables Baseline
(range: 70 – 112)
120 bpm 140 bpm 160 bpm 180 bpm p*
Maximal RV pressure (mmHg) 22.1 ± 2.7 22.6 ± 2.1 22.7 ± 1.9 22.5 ± 2.3 23.0 ± 2.4 0.453
Minimal RV pressure (mmHg) 6.6 ± 2.3 5.6 ± 1.9 5.7 ± 2.1 5.7 ± 2.0 5.9 ± 2.0 0.033
Maximal RV volume (mL) 55.8 ± 9.2 54.0 ± 8.8 a 53.2 ± 9.3 a 52.2 ± 8.7 a,b 51.4 ± 8.6 a,b  < 0.001
Minimal RV volume (mL) 48.6 ± 7.4 46.2 ± 7.5 45.6 ± 7.4 44.8 ± 6.9 a,b 44.7 ± 6.8 a,b  < 0.001
Stroke volume (mL) 7.2 ± 2.1 7.8 ± 2.2 7.6 ± 2.6 7.4 ± 2.5 6.7 ± 2.3 c 0.026
Cardiac output (L/min) 0.72 ± 0.3 0.94 ± 0.3 1.1 ± 0.4 a 1.2 ± 0.4 a 1.2 ± 0.4 a  < 0.001
Ees (mmHg/mL) 4.1 ± 0.9 4.6 ± 1.2 5.0 ± 1.5 4.9 ± 1.3 a 5.1 ± 1.0 a 0.018
Ea (mmHg/mL) 2.3 ± 1.0 2.1 ± 0.6 2.2 ± 0.9 2.2 ± 0.7 2.6 ± 0.9b 0.047
Ees/Ea 2.0 ± 0.5 2.3 ± 0.6 2.4 ± 0.6 2.3 ± 0.4 2.1 ± 0.5 0.313
  1. Data are represented as mean ± standard deviation for normally distributed data or median (interquartile range) for non-normally distributed data
  2. Ea effective arterial elastance, Ees end-systolic elastance, RV right ventricular
  3. *P value of the repeated-measures analysis of variance
  4. aThe value is significantly different from baseline (p < 0.050)
  5. bThe value is significantly different from 120 bpm (p < 0.050)
  6. cThe value is significantly different from 160 bpm (p < 0.050)