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Table 1 Univariable associations between Oclacitinib treated patients (cases) and patients treated with other therapies (controls)

From: The effects of oclacitinib treatment on antimicrobial usage in allergic dogs in primary practice: an Australia wide case-control study

Variable Odds Ratio (95% Confidence Interval) P-value*
Age   < 0.001
1 to 4 years Reference  
 > 4 to 8 years 0.88 (0.77–1) 0.053
 > 8 years 0.58 (0.49–0.68) < 0.001
Sex
 Male Reference 0.676
 Female 0.97 (0.85–1.10)  
Neuter Status
 Neutered Reference < 0.001
 Entire 0.68 (0.56–0.82)  
Breeds   < 0.001
 Small Reference  
 Medium 0.54 (0.44–0.65) < 0.001
 Large 0.5 (0.42–0.59) < 0.001
Total number of courses
 All antimicrobials 0.73 (0.63–0.85) < 0.001
 All glucocorticoids 0.58 (0.48–0.72) < 0.001
 Topical antimicrobials 0.65 (0.52–0.81) < 0.001
 Systemic antimicrobials 0.69 (0.58–0.82) < 0.001
 Topical glucocorticoids 0.67 (0.54–0.84) < 0.001
 Systemic glucocorticoids 0.47 (0.37–0.6) < 0.001
 Antihistamines 0.39 (0.26–0.57) < 0.001
Total number of courses for individual drug
 Cephalexin 0.76 (0.64–0.91) 0.003
 Cefovecin 0.67 (0.43–1.04) 0.076
 Chlorhexidine (2–5%) 0.53 (0.39–0.72) < 0.001
 Neomycin 0.38 (0.27–0.53) < 0.001
 Polymixin B 0.77 (0.57–1.04) 0.091
 Amoxycillin plus clavulanic acid 0.47 (0.34–0.66) < 0.001
Other
 Allergy testing (yes/no) 3.62 (1.18–11.11) 0.025
 Hypoallergenic diet 1.25 (0.9–1.73) 0.175
 Medicated shampoo 0.51 (0.38–0.68) < 0.001
 Flea treatments 0.81 (0.65–1.01) 0.067
Evidence of concurrent skin infection at baseline
 Non-infectious allergic dermatitis Reference < 0.001
 No evidence of concurrent skin infection 0.62 (0.43–0.89) 0.008
 Superficial pyoderma 1.41 (1.41–2.92) < 0.001
 Deep pyoderma Omitted  
Infectious agents in ear at baseline
 No infectious agents present Reference 0.1043
 Cocci present 0.97 (0.63–1.50) 0.907
 Rods present 0.40 (0.13–1.28) 0.124
Malassezia present 1.23 (0.97–1.56) 0.079
  1. **P values are significant at the 0.05 level. The P values for the individual levels of the categorical variables compared to the baseline are given, with a bolded P value for all levels of that categorical variable combined