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Fig. 2 | BMC Veterinary Research

Fig. 2

From: Molecular phylogeny of coronaviruses and host receptors among domestic and close-contact animals reveals subgenome-level conservation, crossover, and divergence

Fig. 2

Polybasic furin cleavage motif of SARS-CoV-2 is present in other coronaviruses. The protein sequence of the furin cleavage site within the S protein, with polybasic amino acid residues conserved among some coronaviruses, is shown. The residues constituting the RRXR motif (where R is an arginine residue and X is another amino acid) are marked with rectangles. The exact RRAR configuration of this motif in SARS-CoV-2 is present in the murine coronavirus but absent in others, including the bat virus and MERS-CoV. The RRXR motif is reversed in others such as the rabbit HKU14 coronavirus and turkey coronavirus. Amino acids are listed in single letter code

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