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Table 2 Univariable Cox regression analysis of variables potentially associated with increased risk of tumor progression and tumor-related death in 64 dogs with low-grade, completely resected stage I cMCT

From: A retrospective study on prophylactic regional lymphadenectomy versus nodal observation only in the management of dogs with stage I, completely resected, low-grade cutaneous mast cell tumors

Variable Tumor progression Tumor-related death
HR (95% CI) P HR (95% CI) P
Breed predisposed to biologically aggressive cMCTs 0.92 (0.16–5.4) 0.925 0.39 (0.03–4.39) 0.443
Age > 7 years 4.02 (0.75–21.44) 0.104 6.3 (0.57–69.79) 0.133
Weight > 30.7 kg 1.38 (0.25–7.71) 0.714 0.99 (0.87–1.12) 0.832
Male sex 0.66 (0.12–3.62) 0.634 0.7 (0.06–7.81) 0.770
Neutering status 0.42 (0.08–2.07) 0.285 0.18 (0.02–2.01) 0.163
Biologically aggressive anatomic location 1.51 (0.18–13.01) 0.705 NA
Tumor diameter > 1.3 cm 0.56 (0.10–3.09) 0.510 2.41 (0.22–26.59) 0.473
Ulceration 2.71 (0.29–25.30) 0.383 NA
Patnaik grade 2 0.41 (0.05–3.59) 0.421 0.35 (0.03–3.88) 0.39
Lack of prophylactic regional lymphadenectomy 43.02 (0.04–41,697.1) 0.284 33.17 (0–1,727,740.46) 0.527