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Table 2 Univariable Cox regression analysis of variables potentially associated with increased risk of tumor progression and tumor-related death in 64 dogs with low-grade, completely resected stage I cMCT

From: A retrospective study on prophylactic regional lymphadenectomy versus nodal observation only in the management of dogs with stage I, completely resected, low-grade cutaneous mast cell tumors

Variable

Tumor progression

Tumor-related death

HR (95% CI)

P

HR (95% CI)

P

Breed predisposed to biologically aggressive cMCTs

0.92 (0.16–5.4)

0.925

0.39 (0.03–4.39)

0.443

Age > 7 years

4.02 (0.75–21.44)

0.104

6.3 (0.57–69.79)

0.133

Weight > 30.7 kg

1.38 (0.25–7.71)

0.714

0.99 (0.87–1.12)

0.832

Male sex

0.66 (0.12–3.62)

0.634

0.7 (0.06–7.81)

0.770

Neutering status

0.42 (0.08–2.07)

0.285

0.18 (0.02–2.01)

0.163

Biologically aggressive anatomic location

1.51 (0.18–13.01)

0.705

NA

Tumor diameter > 1.3 cm

0.56 (0.10–3.09)

0.510

2.41 (0.22–26.59)

0.473

Ulceration

2.71 (0.29–25.30)

0.383

NA

Patnaik grade 2

0.41 (0.05–3.59)

0.421

0.35 (0.03–3.88)

0.39

Lack of prophylactic regional lymphadenectomy

43.02 (0.04–41,697.1)

0.284

33.17 (0–1,727,740.46)

0.527