Characterization of receptor tyrosine kinase activation and biological activity of toceranib phosphate in canine urothelial carcinoma cell lines

Table 1 Patient demographics

Breed	Sex	Age (Yr)	Weight (kg)	Tumor Location	Regional Mets	Distant Mets	Chemo	TOC Therapy
West Highland Terrier	S	7.3	6.5	Trigone	No	No	Yes	No
Scottish Terrier	S	10	9.0	Apex	No	No	Yes	No
Scottish Terrier	C	9	18.0	Apex	No	No	Yes	No
Maltese	C	8	5.2	Trigone, Urethra	No	No	Yes	No
Mixed	S	12	19.1	Apex, Urethra	No	No	No	No
Mixed	C	13	8.0	Apex	No	No	Yes	Yes
Mixed	S	11.2	18.5	Trigone, Urethra	No	No	No	Yes
Shetland Sheepdog	S	12.3	13.1	Dorsal Bladder Wall	No	No	No	Yes
Mixed	C	10	15.0	Trigone, Urethra, Prostate	No	No	Yes	No

The signalment of the patients from which nine primary tumor samples were collected is shown and included breed, sex, age, and weight. The presence of regional metastases (i.e. lymph nodes) and distant metastases (i.e. lung, bone, other intra-abdominal organs) were recorded. Whether patients received chemotherapy (not including toceranib phosphate) is denoted
C castrated, S Spayed

ISSN: 1746-6148