Fig. 4From: An in vivo pharmacokinetic study of metformin microparticles as an oral sustained release formulation in rabbitsMean (n = 5) plasma concentration–time profiles (semi-logarithmic plot) of metformin after single-dose administration via SIV, SPO and SPLA in rabbits. The dose of the drug administered was 5 mg/kg (± SD) (p < 0.05)Back to article page